Assessment of Ischemic Index in Retinal Vascular Diseases Using Ultra-Wide-Field Fluorescein Angiography: Single Versus Summarized Image

Abstract

Background and objective: To compare a single image with a computer-generated summarized

The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis

“…Although both CRVO and BRVO groups displayed high intraocular IL-6 levels, the increase was higher in CRVO than BRVO. Previous studies measuring other parameters such as ischaemic index and aqueous vascular endothelial growth factor concentration, also showed higher results in CRVO compared to BRVO 251,252 , thereby implicating the presence of more aggressive pathogenesis in CRVO. In terms of IL-6 involvement in RVO, IL-6 expression was found to be essential in modulating vascular inflammation through the upregulation of retinal www.nature.com/scientificreports/ vascular endothelial growth factor (VEGF) 253 , indicating an indirect role towards increased endothelial permeability via VEGF.…”

Changes in retinal ischaemic index correlate with recalcitrant macular oedema in retinal vein occlusion: WAVE study

“…We were concerned, however, that FA images in different phases (which would be included in the montage) could interfere with our ability to reliably delineate the regions of NP. In addition, previous reports have shown no significant difference in calculating ISIs for BRVO or CRVO eyes when using montaged or single images 23. Third, our analysis only included subjects receiving ant-VEGF therapy and TRP.…”

Changes in Ocular Hemodynamics after Carotid Artery Angioplasty and Stenting (CAAS) in Patients with Different Severity of Ocular Ischemic Syndrome

“…For patients with iris neovascularization, although CAS cannot restore the visual function, it can delay the development of the disease and improve the life quality and survival rate of patients. [20][21][22][23][24] Figure 2. A.…”