Assessment of ischemic myocardium by strain-rate imaging during adenosine stress echocardiography

Abstract

Combined with adenosine stress echocardiography, SRI can quantitatively differentiate the ischemic from non-ischemic myocardium. epsilon(ps)/epsilon(max) and epsilon(ps)/epsilon(et) can be used as objective indices to identify the ischemic myocardium.

The quantification of dipyridamole induced changes in regional deformation in normal, stunned or infarcted myocardium as measured by strain and strain rate: an experimental study

“…However, as previously shown, baseline values for deformation for each of these substrates were significantly different. Our findings are in agreement with the previous report of Qu et al in which vasodilator infusion did not change contractility as measured by deformation indices in normal and infarcted myocardium [29]. In addition the same group showed decrease in strain during adenosine challenge when baseline flow was reduced by 60-70%.…”

Echocardiographic strain and strain rate imaging — Clinical applications

“…Strain and strain rate measurements appeared to be sensitive indicators for sub-clinical diseases, including arterial hypertension, diabetes, systemic sclerosis, myocardial ischemia, isolated mitral regurgitation and non-ischemic cardiomyopathies, and also very useful for the assessment of myocardial damage after myocardial infarction, evaluation of myocardial revascularization efficiency and prediction of patient outcome with heart failure [11,[28][29][30][31][32][33][34][35][36][37][38][39][40][41]. In a study on 137 consecutive patients with suspected congestive heart failure of different etiologies it was also shown that mean longitudinal LV strain is closely related to plasma brain-type natriuretic peptide (BNP) levels, in patients with both systolic and diastolic heart failure [42].…”

“…Also it was experimentally shown that speckle tracking 2D-strain imaging correctly identifies segmental LV dysfunction induced by the scarring that follows myocardial infarction in rats [46]. Both non-Doppler 2D-strain imaging and TDIderived strain imaging were also used successfully in clinical diagnosis for detection of LV myocardial ischemia and infarction and estimation of myocardial infarction size [31][32][33][34][35][36][37][38]. Strain and strain rate measurements obtained by nonDoppler 2D-strain imaging were found to be highly sensitive and specific for the diagnosis of myocardial infarction [2].…”

Strain and strain rate: An emerging technology in the perioperative period

“…[ 21 ] Strain and SR measurements appeared to be sensitive indicators for various cardiac diseases, including diabetes, myocardial ischemia, arterial hypertension, valvular heart diseases, and also very useful for the assessment of myocardial damage after infarction, evaluation of myocardial revascularization efficiency, and prediction of patient outcome with heart failure. [ 22 23 24 25 ] Abnormal speckle parameters are found in:…”