Understanding tempo-spatial dynamics of land-use/cover (LULC) and its drivers is instrumental in synthesizing knowledge for informed natural resource management planning and associated decisions. The present study investigates tempo-spatial LULC changes, their drivers and the associated impacts in three sub-basins (Zeway, Ketar and Bulbula) in the Central Rift Valley (CRV) of Ethiopia. Satellite imageries of different periods in ArcGIS, field observations, focus group discussions (FGDs) and secondary data were used to analyse the LULC dynamics, their drivers and associated impacts from 1973 to 2014. The overall accuracy of 1973, 2003 and 2014 classification maps was 88.7%, 88.9% and 91.6%, respectively. The analysis results revealed a continuous increase of farmland and town built-up areas at the expense of grasslands, shrub-bush land and woodlands. It further indicated area of open irrigated agriculture, increasing from none to 2.61% of the total area. The FGDs demonstrated agricultural land expansion, resettlement and wood extraction were proximate causes of the observed LULC changes. Population increases, changes in land tenure system and decreased farmland productivity were determined to be the underlying causes of the changes. The FGDs further indicated these changes have negatively affected the natural resources. The present study findings indicate the need to reconsider land-use decision tradeoffs between economic, social and environmental demands, and their implications for other similar areas in Ethiopia and beyond. Quantitative analysis and periodic evaluation of the drivers of such change and the impacts of existing and emerging land-uses in the face of changing climate is recommended to facilitate sustainable use of the fragile ecosystems in the Ethiopian CRV. K E Y W O R D S GIS, Lake Zeway, land-cover, land-use, satellite image | 77 ABERA Et Al.