Assessment of left ventricular function: comparison of cardiac multidetector-row computed tomography with two-dimension standard echocardiography for assessment of left ventricular function

Bansal, Dipika; Singh, Rashmi; Sarkar, Mrinalini; Sureddi, Ravi; Mcbreen, Kelly C.; Griffis, Timothy J.; Sinha, Anjan; Mehta, Jawahar L.

doi:10.1007/s10554-007-9252-6

Cited by 31 publications

(16 citation statements)

References 11 publications

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“…In addition, ventricular wall motion can be assessed visually by the use of cine loop displays of multiple cardiac phases. According to recent reports [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32], measurements for various LV functional parameters with MDCT were correlated and agreed with measurements obtained with MRI, 2D-TTE and ECG-gated single photon emission CT (SPECT). However, the experience with 64-slice MDCT for cardiac function assessment remains limited by small patient numbers and the inclusion of homogeneous patient populations [24][25][26][27][28][29][30][31][32].…”

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confidence: 67%

“…Multiple studies have been published regarding the assessment of LVEF using 4-, 8-, 16-and 64-slice and dual-source MDCT [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][37][38][39][40][41]. LVEF as determined by the use of MDCT showed good or excellent agreement with the respective measurements from cineventriculography, 2D-echocardiography, MRI and SPECT (Table 3).…”

Section: Lvef With Mdctmentioning

confidence: 95%

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Assessment of left ventricular ejection fraction and regional wall motion with 64-slice multidetector CT: a comparison with two-dimensional transthoracic echocardiography

Sm¹,

Kim²,

Jh³

et al. 2010

BJR

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ABSTRACT. The aim of this study was to compare the measurement of left ventricular ejection fraction (LVEF) and regional wall motion using 64-slice multidetector CT (MDCT) with that using two-dimensional transthoracic echocardiography (2D-TTE) in a heterogeneous patient population. In 126 patients with angina pectoris, acute myocardial infarction, chronic myocardial infarction, atypical chest pain without coronary artery disease or valvular heart disease, 64-slice MDCT was performed using retrospective electrocardiography gating without dose modulation. 20 phases of the cardiac cycle were analysed to identify the end-diastolic and end-systolic phases and to assess regional LV wall motion. For these measurements, 2D-TTE served as the reference standard. MDCT and 2D-TTE were performed within 10 days of each other. An excellent correlation between MDCT and 2D-TTE was shown for the evaluation of LVEF (59.2¡11% vs 57.9¡10%, respectively; r50.87). LVEF was slightly overestimated by MDCT, when compared with 2D-TTE, by an average of 1.4¡5.6%. Good agreement was obtained between the use of the two techniques, with 94% of the segments scored identically on both modalities (k50.70). MDCT had a sensitivity of 97% and a specificity of 82% when compared with 2D-TTE as the reference standard. In conclusion, the use of 64-slice MDCT can provide comparable results to those using 2D-TTE for LVEF and regional wall motion assessment in a heterogeneous population.

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confidence: 67%

Section: Lvef With Mdctmentioning

confidence: 95%

Assessment of left ventricular ejection fraction and regional wall motion with 64-slice multidetector CT: a comparison with two-dimensional transthoracic echocardiography

Sm¹,

Kim²,

Jh³

et al. 2010

BJR

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“…Recent studies that compared the left ventricular systolic function values obtained by echocardiography and MDCT have demonstrated good correlations (5,14,15). However, left ventricular volume values calculated by MDCT were significantly higher than those obtained by echocardiography.…”

Section: Discussionmentioning

confidence: 98%

Assessment of global left ventricular systolic function with multidetector CT and 2-d echocardiography: a comparison between reconstructions of 1 mm and 2 mm slice thickness at MDCT

Vural

Uçar²,

Selvi³

et al. 2009

Diagn Interv Radiol

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Multidetector computed tomography (MDCT) is a good, noninvasive alternative for the diagnosis and follow-up of coronary artery disease. It is also a highly reliable technique for detecting coronary artery anomalies and evaluating bypass graft patency (1-4). Left ventricular end-diastolic volume (EDV) and end-systolic volume (ESV) can also be calculated because the continuous acquisition of CT in spiral mode during ECG gating generates a data set that contains all information about the phases of the cardiac cycle.Accurate determination of left ventricular ejection fraction (EF) is important for clinical diagnosis, risk stratification and prognosis estimation in many patients with cardiac disease. Currently, magnetic resonance imaging (MRI) is the gold standard technique for assessing left ventricular volumes and EF. However, MRI is a costly, time-consuming examination and is not widely available for this purpose. By comparison, 2D echocardiography (2DE) is more readily available for assessing left ventricular systolic function due to its lower cost.The primary purpose of this study was to compare 16-slice MDCT and 2DE in terms of displaying left ventricular systolic function. As a secondary target, reconstructions based on 1-mm-and 2-mm-thick slices were compared for their ability to analyze left ventricular systolic function. Materials and methods PatientsPatients who were referred to the radiology department to be evaluated for coronary artery disease by MDCT were recruited. Exclusion criteria were renal insufficiency (plasma creatinine >2 mg/dL), allergy to iodinated contrast media and atrial fibrillation. A subsequent echocardiogram was performed on the same day as MDCT.The study was approved by the ethics committee of our institution, and all patients gave informed consent for participation in the study. Multidetector CTMDCT was performed using a 16-detector Toshiba Aquilion system (Toshiba Medical Systems, Otawara, Japan). The imaging and reconstruction parameters were as follows: detector collimation, 16 mm x 0.75 mm; voltage, 120 kV; effective tube current, 350 mA or 400 mA (depending on the patient size) and gantry rotation time, 420-500 ms. All CT scans were obtained in the craniocaudal direction. Image acquisition was performed during an inspiratory breath-hold. If not contraindicated, patients who had a prescan heart rate exceeding 70 beats per minute were given a single oral dose of 100 mg metoprolol 1 hour before the examination.A 100-ml bolus of a non-ionic contrast agent (Iomeprol, Iomeron 350 mgI/mL, Bracco, Italy) was injected in the antebrachial vein with a flow PURPOSETo compare multidetector computed tomography (MDCT) and two-dimensional transthoracic echocardiography (2DE) for left ventricular ejection fraction (EF); and to make comparison between reconstructions of 1-mm and 2-mm slice thickness at MDCT in left ventricular analysis by using a semiautomated segmentation algorithm. MATERIALS AND METHODSIn 43 patients global left ventricular systolic function was assessed by using both MDCT an...

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“…The accurate and reproducible quantitative assessment of global LV functional parameters requires sufficient temporal resolution, and a number of studies have been conducted to assess LV global function, showing good or excellent agreement with the competitive image modalities using 4-, 8-, 16-and 64-slice MDCT [11,[15][16][17][18][19][20]. However, in those studies patients were administered beta-blockers, and all those studies also revealed a systematic deviation of LV volumes and EF.…”

Section: Discussionmentioning

confidence: 99%

Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography

Kim

Park

et al. 2011

Int J Cardiovasc Imaging

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To compare the measurement of global left-ventricular (LV) function parameters of 64-slice multidetector-row computed tomography (MDCT) between 20- and 10-reconstruction phases. Fifty five patients with suspected or known coronary artery disease underwent 64-slice MDCT. LV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were measured from MDCT data sets using threshold-based volume segmentation and reconstruction at every 5% (20 phases) and 10% (10 phases) step through the R-R interval. These global functional parameters were compared to those obtained via two-dimensional transthoracic echocardiography (2D-TTE), considering the reference standard. The required time for CT data analysis was checked. Agreement for parameters of LV global function was determined using Pearson's correlation coefficient (r) and Bland-Altman analysis. LV volumes (EDV(-5%) 87.5 ± 17.1 ml, EDV(-10%) 87.7 ± 16.3 ml; ESV(-5%) 32.4 ± 10.6 ml, ESV(-10%) 31.9 ± 9.9 ml; SV(-5%) 55.1 ± 10.5 ml, SV(-10%) 55.8 ± 9.9 ml; mean ± SD) and EF (EF(-5%) 63.4 ± 6.2%, EF(-10%) 63.9 ± 5.8%) did not differ significantly between the 20- and 10 phase reconstructions, and evidenced good to excellent correlation (r = 0.786-0.896, all P < 0.001) with the 2D-TTE results. The mean required time for CT data analysis in the 20- and 10 phase reconstructions were 15.5 ± 4.0 and 7.3 ± 2.5 min. Within MDCT, using 10-phase image reconstruction is sufficient to evaluate LV volumes and EF, and is also more time-effective than 20-phase reconstruction.

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Assessment of left ventricular function: comparison of cardiac multidetector-row computed tomography with two-dimension standard echocardiography for assessment of left ventricular function

Abstract: MDCT can be a useful tool to measure LVEF while patients are undergoing CT coronary angiography.

Cited by 31 publications

References 11 publications

Assessment of left ventricular ejection fraction and regional wall motion with 64-slice multidetector CT: a comparison with two-dimensional transthoracic echocardiography

Assessment of left ventricular ejection fraction and regional wall motion with 64-slice multidetector CT: a comparison with two-dimensional transthoracic echocardiography

Assessment of global left ventricular systolic function with multidetector CT and 2-d echocardiography: a comparison between reconstructions of 1 mm and 2 mm slice thickness at MDCT

Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography

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