Assessment of Prevalence and Antibiogram of NFGNB isolates in a Tertiary care Hospital, Dehradun

Abstract

Non-fermenting Gram Negative Bacilli (NFGNB) is emerging as a major cause of nosocomial infections as they exhibit great multidrug resistance thereby posing difficulty in combating the infections. Studies on assessing the prevalence rate and antibiogram of NFGNB is necessary for proper management of infections caused by them as there are high chances of regional variation in predominance and antimicrobial susceptibility pattern of NFGNB. Aim of the present study was to assess the prevalence rate of NFGNB along with antimicrobial sensitivity pattern revealing their drug sensitivity and resistance among the patients attending tertiary care hospital of varied age groups. A total of 1000 various clinical specimens were received in laboratory during the period of 4 months (August 2020-Novemebr 2020) and were subjected to processing using Vitek-2 compact system. Among 1000 clinical samples 328 yielded NFGNB i.e., Pseudomonas aeruginosa, Acinetobacter baumannii, Achromobacter Xylosoxidans, Stenotrophomonas maltophilia and Burkholderia cepcia. Pseudomonas aeruginosa (51.82%) and Acinetobacter baumannii (39.63%) were most prominent NFGNB isolates. Results showed that although NFGNB were found to be resistant against most of the subjected antibiotics but considerable intensity of effectiveness was also recorded against Colistin. Accurate, rapid identification and antimicrobial susceptibility testing of NFGNB by Vitek 2, is required in early diagnosis, treatment and proper management of patients will reduce emergence of MDR strains of NFGNB.

Gas chromatographic mass spectroscopic evaluation of Punarnavadi Kwatha

“…4 .1.2,3 benzene triol is the compound from the ingredient of Terminalia chebula Retz as per the previous GCMS work. 5 3-Hydroxy-4-methoxybenzoic acid from the ingredient Picrorhiza kurroa auct non-Royle. As per the previous gcms study the compound Tetradecanoic acid was present in stem of Tinospora cordifolia (Wild).…”

Radical Copolymerization and Determination of Thermal Stability of Some New Substituted Phenyl Maleimide Polymers

“…N-Substituted maleimide copolymers with MMA, acrylates, butylacrylate showed excellent thermal properties accompanied by characteristic polymerization behavior and it has been approved by experimentally. But excess of N-substituted maleimide moiety, increases chain-rigidity, causes the drop of mechanical properties such as tensile strength and impact strength and achieved with enhancement of Tg-value [6][7][8][9][10][11][12][13][14]. Here we are focused to synthesis of some newly of N-Phenyl maleimide substituted polymer and determination of polymer shape in the solution by using of Kuhan-mark Howink Sakwada equation.…”