Assessment of skin lesions and skin cancer using simple electrical impedance indices

Åberg, Peter; Nicander, Ingrid; Holmgren, Ulf; Geladi, Paul; Ollmar, Stig

doi:10.1034/j.1600-0846.2003.00017.x

Cited by 42 publications

(39 citation statements)

References 20 publications

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“…Posljednjih godina ove se metode sve češće primjenjuju u detekciji tumorskih promjena u različitim tkivima. Tako se impedancijskom spektrografijom mogu procjenjivati različite tumorske tvorbe na koži, u dojci i na sluznici ženskih reproduktivnih organa (3,4,10,11). Bioimpedacijska mjerenja već su ustaljena u stomatološ-koj praksi korištenjem različitih apeksnih lokatora za određi-www.ascro.hr…”

Section: Uvodunclassified

“…Lately, these methods have been increasingly used in the detection of tumors in different tissues. Thus, EI spectroscopy can be used to assess different tumor lesions on the skin, breast and female reproductive organs (3,4,10,11). The application of EI measurements has already been established in dentistry through the use of different apex locators for the root canal length de-…”

Section: Introductionmentioning

confidence: 99%

“…Diagnostic methods based on EI measurement are used in different fields of medicine. EI spectroscopy, which is the most widely used method, has a long history (Fere and Tarhanov 1888.g), and has been mostly used for the assessment of skin lesions (3)(4)(5)(6). EI is also applied in the assessment of the severity of muscle ischaemia (2).…”

Section: Introductionmentioning

confidence: 99%

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Mapping Electrical Impedance Spectra of the Healthy Oral Mucosa: a Pilot Study

Richter

Alajbeg

Boras

et al. 2015

Acta Stomatol Croat

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Adresa za dopisivanje izv. prof. dr. sc. Vlaho Brailo Stomatološki fakultet Sveučilišta u Zagrebu Zavod za oralnu medicinu Gundulićeva 5, 10 000 Zagreb brailo@sfzg.hr Sažetak Svrha ispitivanja: Bioimpedancija je otpor prolasku električne struje kroz tkivo i ovisi o njegovoj strukturi i kemijskom sastavu. Svrha istraživanja bila je mapirati bioimpedancijske spektre za svaku regiju usne šupljine. Ispitanici i postupci: U mjerenju bioimpedancije sudjelovalo je tridesetero ispitanika s urednim nalazom oralne sluznice, a obavljalo se na 14 lokalizacija u usnoj šupljini s lijeve i desne strane te je ponovljeno nakon sedam i četrnaest dana. Rezultati: Najniže vrijednosti izmjerene su na dorzumu jezika, a najviše na tvrdom nepcu. Nije ustanovljena statistički značajna razlika između mjerenja na lijevoj i desnoj strani. Statistički značajno više vrijednosti izmjerene su ženama na sluznici gornje usne, dorzumu jezika i na ventralnom dijelu jezika. Utvrđena je statistički značajna razlika između nepušača i pušača na sluznici donje usne i sluznici dna usne šuplji-ne. Vrijednosti bioimpedancije bile su u negativnoj korelaciji s količinom sline na sluznici gornje usne, na tvrdom nepcu, dorzumu jezika i na podjezičnoj sluznici. Mjerenja pri niskim frekvencijama imala su veću varijabilnost. Zaključak: Vrijednosti bioimpedancije najčešće ovise o stupnju keratinizacije sluznice. Na njihove vrijednosti vjerojatno utječu demografski i klinički čimbenici, što je potrebno razjasniti u daljnjim studijama s većim brojem ispitanika. Ključne riječi električna impedancija, oralna sluznicaZavod za oralnu medicinu Stomatološkog fakulteta Sveučilišta

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Section: Uvodunclassified

Section: Introductionmentioning

confidence: 99%

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Mapping Electrical Impedance Spectra of the Healthy Oral Mucosa: a Pilot Study

Richter

Alajbeg

Boras

et al. 2015

Acta Stomatol Croat

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“…The proper compensation of temperature effects is thus of paramount importance for glucose monitoring and other medical diagnosis tools based on impedance measurements e.g. [1,2,12,23,39]. However, its relevance is not limited to medical applications, but in general concerns non-destructive evaluations of materials using dielectric spectroscopy [28,37].…”

Section: Introductionmentioning

confidence: 99%

The compensation of perturbing temperature fluctuation in glucose monitoring technologies based on impedance spectroscopy

et al. 2007

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Non-invasive glucose monitoring techniques based on impedance spectroscopy are affected by a variety of perturbing effects. In order to use the impedance as a glucose measure, these perturbing effects need to be quantified and compensated. Since effects induced by temperature fluctuations certainly rank among the severest perturbations, a clinical study was carried out to establish whether temperature, as a perturbing factor, could be compensated for in impedance spectroscopy. The results as well as a concept allowing for the compensation of perturbing temperature fluctuations are presented here. The compensation technique described is a generic approach that, in principle, can be applied to compensate most perturbation effects provided that there are now multiplicative interactions between the variable of interest (in our case the glucose) and the perturbations. The results allow for the determination of the minimum required sensitivity of an impedance spectrometer to glucose in order to be operational in home-use conditions. Furthermore, the data can be used to estimate if a universal temperature compensation can be applied or if an individual calibration is necessary. For instance, applying a universal temperature compensation and requiring an application range of +/-5 degrees C, the minimum required sensitivity of the minimum impedance and frequency in a sensor-skin RLC circuit to resolve glucose variations equivalent to 10 mg/dl is 0.85 Omega/mg/dl and 0.14 MHz/mg/dl, respectively. The sensitivity requirements reduce by about a factor 1.6, if for each subject an individual calibration is carried out. Depending on the measure and the calibration procedure, the required sensitivities are a factor 3-50 greater than those reported in the literature. Thus, in order to be operational in home-use conditions, the signal-to-noise ratio (S/N) of existing impedance-based monitoring platforms using RLC circuits need to be improved by about one order of magnitude. In order to make non-invasive glucose monitoring possible we, therefore, suggest some measures that may improve the S/N by the required factor.

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“…They measured the impedance characteristics of the skin and its appearance before and after SLS application and reported that various impedance changes could be used for quantitative evaluation of the skin stimulus. From around 2003, the group attempted to develop a new melanoma diagnostic equipment using the same theory [22]. Figure 3 shows outline of electrode they developed.…”

Section: Impedance Measurementsmentioning

confidence: 99%

Recent Advances in Diagnostic Technologies for Melanoma

Nagaoka

2016

ABE

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Melanoma is a malignant tumor occurring typically in the skin. Advanced melanoma has very poor prognosis, and is also called the king of cancer . On the other hand, early-stage melanomas are known to be cured completely by relatively simple treatments. Therefore, early detection and treatment of melanomas is very important. However, many melanomas are still diagnosed by subjective evaluation of a physician, in other words, visual inspection. Recently, the demands for development of quantitative melanoma diagnostic technology are increasing. Much research on melanoma diagnosis has progressed in response to these demands. This review introduces some recent advances in melanoma diagnosis using spectral imaging techniques, impedance measurement and diagnostic image analysis, and also brie y describes a novel biological agent against melanoma developed in Japan. A high-quality system using multispectral imaging technique has attracted attention, but the low speci city has been regarded as a problem. It should be noted that descriptions of medical contents are limited because this review is written for engineers and researchers.

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Assessment of skin lesions and skin cancer using simple electrical impedance indices

Abstract: There are clear statistical differences between impedance of common lesions and control skin. With some further developments, the impedance technique can be useful as a diagnostic decision support tool for skin cancer assessment.

Cited by 42 publications

References 20 publications

Mapping Electrical Impedance Spectra of the Healthy Oral Mucosa: a Pilot Study

Mapping Electrical Impedance Spectra of the Healthy Oral Mucosa: a Pilot Study

The compensation of perturbing temperature fluctuation in glucose monitoring technologies based on impedance spectroscopy

Recent Advances in Diagnostic Technologies for Melanoma

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