Assessment of speciation and in vitro bioaccessibility of selenium in Se-enriched Pleurotus ostreatus and potential health risks

Zhou, Fei; Dinh, Quang Toan; Yang, Wenxiao; Wang, Mengke; Xue, Mingyue; Bañuelos, Gary S.; Liang, Dongli

doi:10.1016/j.ecoenv.2019.109675

Cited by 28 publications

(9 citation statements)

References 41 publications

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“…The order of bioaccessibility of Se for different gastrointestinal digestion simulation methods in gastricand intestinal was as follows: PBET > UBM (unified bioaccessibility method) > SBRC (solubility bioaccessibility research consortium method) > IVG (in vitro gastrointestinal method; Zhou et al, 2020 ). The PBET method has become a common evaluation method for evaluating the bioaccessibility of Se ( Zhou et al, 2019 ; Muleya et al, 2021 ). Hitherto many studies on Se bioaccessibility in green vegetables have been carried out, including on Se-enriched leeks ( Lavu et al, 2012 ), potato ( Dong et al, 2021 ), lettuce ( Do et al, 2017 ), and Se-enriched crops, such as maize ( Muleya et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Soil and foliar selenium application: Impact on accumulation, speciation, and bioaccessibility of selenium in wheat (Triticum aestivum L.)

et al. 2022

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A comprehensive study in selenium (Se) biofortification of staple food is vital for the prevention of Se-deficiency-related diseases in human beings. Thus, the roles of exogenous Se species, application methods and rates, and wheat growth stages were investigated on Se accumulation in different parts of wheat plant, and on Se speciation and bioaccessibility in whole wheat and white all-purpose flours. Soil Se application at 2 mg kg–1 increased grains yield by 6% compared to control (no Se), while no significant effects on yield were observed with foliar Se treatments. Foliar and soil Se application of either selenate or selenite significantly increased the Se content in different parts of wheat, while selenate had higher bioavailability than selenite in the soil. Regardless of Se application methods, the Se content of the first node was always higher than the first internode. Selenomethionine (SeMet; 87–96%) and selenocystine (SeCys2; 4–13%) were the main Se species identified in grains of wheat. The percentage of SeMet increased by 6% in soil with applied selenite and selenate treatments at 0.5 mg kg–1 and decreased by 12% compared with soil applied selenite and selenate at 2 mg kg–1, respectively. In addition, flour processing resulted in losses of Se; the losses were 12–68% in white all-purpose flour compared with whole wheat flour. The Se bioaccessibility in whole wheat and white all-purpose flours for all Se treatments ranged from 6 to 38%. In summary, foliar application of 5 mg L–1 Se(IV) produced wheat grains that when grounds into whole wheat flour, was the most efficient strategy in producing Se-biofortified wheat. This study provides an important reference for the future development of high-quality and efficient Se-enriched wheat and wheat flour processing.

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Section: Introductionmentioning

confidence: 99%

Soil and foliar selenium application: Impact on accumulation, speciation, and bioaccessibility of selenium in wheat (Triticum aestivum L.)

et al. 2022

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“…1 Some reports have illustrated that Se can reduce toxicity of arsenic accumulation to protect against skin lesions induced by arsenic. 2 The disproportional distribution of Se leads Se deficiency to be a global matter, where the content of Se in soil is particularly low and insufficient Se intake will bring certain health disorders, typically Keshan disease. 3 It was reported that more than 15% of the global population dispersed in 366 counties has been facing health problems associated with Se deficiency.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Selenium (Se) is an essential metalloid element and micronutrient for all mammals, which functions as the center of most Se-dependent enzymes, such as glutathione peroxidases and thioredoxin reductases, in antioxidant defense or immune responses, and it works physiologically by Se-containing amino acids . Some reports have illustrated that Se can reduce toxicity of arsenic accumulation to protect against skin lesions induced by arsenic . The disproportional distribution of Se leads Se deficiency to be a global matter, where the content of Se in soil is particularly low and insufficient Se intake will bring certain health disorders, typically Keshan disease .…”

Section: Introductionmentioning

confidence: 99%

Investigation of Differentially Expressed Proteins Induced by Alteration of Natural Se Uptake with Ultrahigh-Performance Liquid Chromatography Quadrupole Orbitrap Uncovers the Potential Nutritional Value in Se-Enriched Green Tea

Jia

Liu

Shi

et al. 2020

J. Agric. Food Chem.

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Se-enriched green tea, with an increasing consumption, is the shoot of tea plants grown naturally in a seleniferous region. A label-free proteomic strategy based on ultrahigh-performance liquid chromatography quadrupole Orbitrap was applied to characterize and distinguish the difference between the Se-enriched and normal green tea with a total of 283 proteins identified and 264 proteins quantified, in which 96 proteins were observed different. The expressions of 10 proteins were upregulated and 40 proteins were downregulated (p < 0.05) in Se-enriched samples. Gene ontology, Kyoto Encyclopedia of Genes and Genomes pathway, and protein–protein interaction (PPI) network analysis results indicated that these differentially expressed proteins significantly interacted and were involved in secondary metabolites and inflammatory response biological processes. Furthermore, the expression of methyl-jasmonate- and ethylene-related genes changed significantly in Se-enriched green tea, and catalase proteins were employed as the center of the pathway that changed significantly in the PPI network. These results associating with the current knowledge of selenium in soil–plant cycling revealed that organic selenium was synthesized in green tea, which provided novel information on Se assimilation in Camellia sinensis and improved the understanding of Se-enriched green tea as a possible ideal selenium supplement in daily life.

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“…SeMet and MeSeCys reached their maximum values when irrigated with 20 mg Se/L, whereas 10 mg Se/L was required for SeCys in Agaricus bisporus fruiting bodies [33]. Studies have also shown that mushrooms such as Pleurotus ostreatus [34] and L. edodes [35], given Se fortification, yield good bioaccessibility in the form of SeMet. Moreover, MeSeCys was identified in H. erinaceus [12], Auricularia auricular [7], and P. ostreatus [34] fruiting bodies.…”

Section: Discussionmentioning

confidence: 99%

“…Studies have also shown that mushrooms such as Pleurotus ostreatus [34] and L. edodes [35], given Se fortification, yield good bioaccessibility in the form of SeMet. Moreover, MeSeCys was identified in H. erinaceus [12], Auricularia auricular [7], and P. ostreatus [34] fruiting bodies. Here, 50 ppm Na 2 SeO 3 was beneficial for SeCys 2 and SeMet production throughout the whole process, whereas the content of SeCys 2 and SeMet decreased in G. lucidum cultured with 200 ppm Na 2 SeO 3 .…”

Section: Discussionmentioning

confidence: 99%

Influence of Selenium Biofortification on the Growth and Bioactive Metabolites of Ganoderma lucidum

Zhu

Wang

et al. 2021

Foods

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Selenium biofortification of edible and medicinal mushrooms is an effective way to produce selenium-enriched food supplements. Ganoderma lucidum is the typical one with excellent biological activity. This study investigated G. lucidum growth and bioactive metabolites alterations during liquid culture with different concentrations of selenite. Low selenium levels did not affect growth and mycelia morphology, whereas high selenium levels negatively influenced growth, dramatically decreased biomass, caused nucleic acid and protein leakage, damaged cell walls and membranes, and resulted in indicators such as degraded cells, a red color, and an unpleasant odor. Through headspace-solid phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS) analysis, ten volatile Se compounds were identified in G. lucidum with 200 ppm selenite, which led to an odor change, whereas only three with 50 ppm selenite. SeMet was the major selenoamino acid in the 50 ppm selenite group by high-performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS), but more MeSeCys was produced with 200 ppm selenite. Polysaccharide yields were promoted and inhibited with 50 and 200 ppm selenite, respectively. These results provide comprehensive insights into the effects of selenite on G. lucidum in liquid culture and are beneficial for functional selenium-enriched mushroom production and improving nutritive values.

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Assessment of speciation and in vitro bioaccessibility of selenium in Se-enriched Pleurotus ostreatus and potential health risks

Cited by 28 publications

References 41 publications

Soil and foliar selenium application: Impact on accumulation, speciation, and bioaccessibility of selenium in wheat (Triticum aestivum L.)

Soil and foliar selenium application: Impact on accumulation, speciation, and bioaccessibility of selenium in wheat (Triticum aestivum L.)

Investigation of Differentially Expressed Proteins Induced by Alteration of Natural Se Uptake with Ultrahigh-Performance Liquid Chromatography Quadrupole Orbitrap Uncovers the Potential Nutritional Value in Se-Enriched Green Tea

Influence of Selenium Biofortification on the Growth and Bioactive Metabolites of Ganoderma lucidum

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