Assessment of the Antioxidant Activity of Silybum marianum Extract and Its Protective Effect against DNA Oxidation, Protein Damage and Lipid Peroxidation

Serçe, Aynur; Toptancı, Bircan Çeken; Tanrıkut, Sevil Emen; Altaş, Sevcan; Kızıl, Göksel; Kızıl, Süleyman; Kızıl, Murat

doi:10.17113/ftb.54.04.16.4323

Cited by 28 publications

(15 citation statements)

References 20 publications

(23 reference statements)

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“…(2014) value as (20.92 mg/g). Moreover, Serce et al., (2016) finding are supported current results that milk thistle contained phenolic contents as 620.0 µg/g in ethanol extract. The finding of Pereira et al., (2014) are synchronized 23.26 mg/g with the current results.…”

Section: Resultssupporting

confidence: 73%

RETRACTED: Biochemical profile of milk thistle (Silybum Marianum L.) with special reference to silymarin content

Aziz

Saeed

Ahmad

et al. 2020

Food Science & Nutrition

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The main objective of current study was to evaluate the antioxidant potential and nutritional composition of milk thistle with special reference to silymarin. For the purpose, different varieties of milk thistle were procured from three different cities of Pakistan. The study was comprised of three different phases. In 1st phase, nutritional composition, that is, moisture, fat, protein, fiber, and nitrogen free extract, was determined according to their respective methods. Moreover, antioxidant potential and quantification of silymarin content were explored in 2nd phase. Furthermore, in last phase, milk thistle seeds tea was developed and evaluated for nutritional and sensorial characteristics. At last, data obtained from each parameter was subjected to appropriate statistical design to determine the level of significance. Results showed significant difference in the nutritional and chemical composition of different milk thistle varieties as well as locations. Moreover, moisture content, ash content, fat content, fiber content, protein content, and NFE varied from 6.27% to 5.01%, 2.37 to 1.25%, 23.19 to 19.74%, 7.4 to 4.39%, 30.09 to 20.74%, and 45.42 to 34.13%, respectively. Furthermore, silymarin content quantified though HPLC ranged from 1669.5 mg/g to 1607.6 mg/g for soxhlet extract whereas, 1,840.6 mg/g to 1765.9 mg/g for microwave‐assisted extraction extract. Conclusively, it was depicted from the results that in case of variety, Blue was the best than White whereas, Islamabad was best in case of location.

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Section: Resultssupporting

confidence: 73%

RETRACTED: Biochemical profile of milk thistle (Silybum Marianum L.) with special reference to silymarin content

Aziz

Saeed

Ahmad

et al. 2020

Food Science & Nutrition

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“…High antioxidant activities were examined within all size fractions of this species; however, the A250 fraction had the highest activity, which reached 101.95 mg AAE/g flour. The antioxidant activity of milk thistle seeds was previously given in correlation with bioactive flavonolignans (silymarin complex) [48,54]. Moreover, our data suggested the accumulation of antioxidants in the surface structure of milk thistle seeds.…”

Section: Functional Characteristics Of Oilseed Cake Flourssupporting

confidence: 64%

Oilseed Cake Flour Composition, Functional Properties and Antioxidant Potential as Effects of Sieving and Species Differences

Bárta

Bártová

Jarošová

et al. 2021

Foods

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Oilseed cakes are produced as a by-product of oil pressing and are mostly used as feed. Their use for human consumption is due to the functional properties and benefits for human health. Herein, oilseed cake flours of eight species (flax, hemp, milk thistle, poppy, pumpkin, rapeseed, safflower, sunflower) were sieved into fractions above (A250) and below (B250) 250 µm. The chemical composition, SDS-PAGE profiles, colour, functional properties and antioxidant activities of these flours were evaluated. The B250 fractions were evaluated as being protein and ash rich, reaching crude protein and ash content ranging from 31.78% (milk thistle) to 57.47% (pumpkin) and from 5.0% (flax) to 11.19% (poppy), respectively. A high content of carbohydrates was found in the flours of hemp, milk thistle and safflower with a significant increase for the A250 fraction, with a subsequent relation to a high water holding capacity (WHC) for the A250 fraction (flax, poppy, pumpkin and sunflower). The A250 milk thistle flour was found to have the richest in polyphenols content (TPC) (40.89 mg GAE/g), with the highest antioxidant activity using an ABTS•+ assay (101.95 mg AAE/g). The A250 fraction for all the species exhibited lower lightness than the B250 fraction. The obtained results indicate that sieving oilseed flour with the aim to prepare flours with specific functional characteristics and composition is efficient only in combination with a particular species.

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“…Seed extracts of S. marianum collected from 30 different regions of Greece have been reported to have antioxidant potential [21]. It was reported that ethanol and petroleum ether extract of the seeds of S. marianum collected from Turkey were the antioxidant potential [22]. In China, ethanol extracts of leaf, man stem, root, fruit receptacle and pappus of S. marianum were used.…”

Section: Antioxidant and Oxidant Potentialmentioning

confidence: 99%

Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)

Mohammed

Pehlivan

Sevindik

2020

International Journal of Secondary Metabolite

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In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using ethanol extracts. Antibacterial and antifungal activity were determined using agar dilution method. Antibacterial activity was determined against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii). Antifungal activity was determined against Candida albicans, C. krusei and C. glabrata. As a result of the studies, it was determined that plant extracts have high antioxidant activity. It was also found to be effective against bacteria at 25-400 µg/mL concentrations. Plant extracts were found to be more effective against gram negative bacteria. It was found to be effective against Candida species at 400-800 µg/mL concentrations. As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.

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Assessment of the Antioxidant Activity of Silybum marianum Extract and Its Protective Effect against DNA Oxidation, Protein Damage and Lipid Peroxidation

Cited by 28 publications

References 20 publications

RETRACTED: Biochemical profile of milk thistle (Silybum Marianum L.) with special reference to silymarin content

RETRACTED: Biochemical profile of milk thistle (Silybum Marianum L.) with special reference to silymarin content

Oilseed Cake Flour Composition, Functional Properties and Antioxidant Potential as Effects of Sieving and Species Differences

Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)

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