Assessment of the cross-reactivity and binding sites characterisation of a propazine-imprinted polymer using the Langmuir-Freundlich isotherm

Abstract

In this paper, the Langmuir-Freundlich isotherm is used to model the interaction of several triazines (desethylatrazine, desisopropylatrazine, simazine, atrazine, propazine and prometryn) with a propazine-imprinted polymer and to explain the observed cross-reactivity. Different rebinding experiments (each herbicide alone or all together in a mixture) were carried out and the experimental binding isotherms were fitted to the Langmuir-Freundlich isotherm. The fitting coefficients obtained (total number of binding sites, mean binding affinity and heterogeneity index) allowed the description of the kind of binding sites present in the imprinted polymer under study. It was concluded that the recognition mechanism was mainly governed by the molecular size although slight differences in the molecular structure may also play an important role. The obtained results suggest that the use of this new methodology can open new pathways for understanding how molecular recognition in imprinted polymers takes place.

Utilizing the Cross-Reactivity of MIPs

“…There are more publications presented in the recent past that underline the utility of the crossreactivity potential of MIPs and we expect more reports on this theme to be published in the future [14][15][16][17].…”

Characterisation and quality assessment of binding sites on a propazine-imprinted polymer prepared by precipitation polymerisation

“…In order to confirm the suitability of this strategy to prepare high quality molecularly imprinted polymers with homogenous binding site distribution, a new polymer using a different template (propazine) was prepared (MIP-P) and evaluated in the present work. Thus, the main aim of this paper is the characterisation and evaluation of the homogeneity of the binding sites of this polymer and to compare the results with those obtained for another non-covalent propazine-imprinted polymer prepared by bulk polymerisation (MIP-B) in a previous work [13]. This study was carried out by equilibrium rebinding experiments of not only propazine (template molecule) but also of other structurally related compounds able to interact with the obtained polymers.…”

Electrochemical sensing for the detection of 2,4-dichlorophenoxy acetic acid using molecularly imprinted polymer membrane

“…It has been found that template membrane can be stored at room temperature in buffer solution for 12 weeks without showing any loss in sensitivity. The selectivity of the imprinted polymers seems to be governed by number and nature of interaction between substrate and polymer stationary phases, as well as by the shape of the print molecule and cavities in the polymers [16][17][18]. The nature of observed sensor responses might be explained by an assumption that interaction between the template molecule with the polymeric domain results in a conformational reorganization of the polymeric structure, affecting the diffusion of co-and counter ions.…”