Assessment of the Cytokine-Producing Resource of Tumor Biopsy Samples from Patients with Invasive Carcinoma of No Special Type and with Non-Malignant Breast Diseases

Autenshlyus, A. I.; Studenikina, A. A.; Bernado, A V; Михайлова, Е. С.; Проскура, А В; Sidorov, S. V.; Вараксин, Н. А.; Lyakhovich, V. V.

doi:10.1134/s1990750820010047

Cited by 2 publications

(2 citation statements)

References 20 publications

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“…Women with FBM often present with the complaint of a mass and physical examination usually reveals a painless, smooth mass with discrete borders 6 . The mass is classified into 3 subgroups histopathologically; hyperplastic fibrous cyst, adenosis, and papillomatosis 7 . In addition to physical examination, ultrasonography and mammography are frequently used as imaging modalities in the diagnosis of FBM 2 .…”

Section: Introductionmentioning

confidence: 99%

Kan 25-hidroksi D vitamini düzeyinin fibrokistik meme hastalığı ve meme yoğunluğu ile ilişkisi

Bolat

ERDOĞAN²

2022

Cukurova Medical Journal

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Öz Purpose:The aim of this study is to evaluate the association of blood 25-hydroxy vitamin D levels with fibrocystic breast masses and breast patterns. Materials and Methods:The study included 612 patients who presented with breast complaints or referred for routine screening between 2018-2021 and were requested to have breast ultrasonography (USG) and mammography (MG) examinations. Patients were divided into two groups; group 1 consisted of women with fibrocystic mass (BI-RADS 2-3) and group 2 consisted of women without breast mass (BI-RADS 1). These two groups were compared by age, breast USG, MG results, and blood 25hydroxy vitamin D levels. Results: Of the 612 patients, 310 (51%) had fibrocystic mass in their breasts, while 302 (49%) had normal breasts. The mean age of both groups was similar. Those with fibrocystic mass in the breast had lower vitamin D levels and higher breast density than the control group. The group with higher breast density had lower vitamin D levels, and there was a negative correlation between vitamin D level and breast density Conclusion: Our study revealed that women with fibrocystic masses in their breasts (BI-RADS2 and BI-RADS3) had higher breast density and lower vitamin D levels than women without breast mass. Amaç: Bu çalışmanın amacı kan 25-hidroksi D vitamin seviyesinin memenin fibrokistik kitleleri ve meme paternleri ile olan ilişkisini değerlendirmektir. Gereç ve Yöntem: Çalışmaya 2018-2021 yılları arasında meme şikayeti veya rutin tarama için başvuran, meme ultrasonografi (USG) ve mamografi (MG) tetkiki istenen 612 hasta dahil edildi. Memede fibrokistik kitlesi olanlar (BI-RADS 2-3) grup 1 ve memede kitlesi olmayanlar (BI-RADS 1) grup 2 olmak üzere hastalar iki gruba ayrıldı. Her iki grup; yaş, meme USG, MG sonuçları ve kan 25-hidroksi D vitamin seviyeleri açısından karşılaştırıldı. Bulgular: Çalışmaya dahil edilen kadınların 310 (%51)'da memede fibrokistik kitle tespit edilirken, 302 (%49)'sinin memesi normaldi. Her iki grubun yaş ortalaması benzerdi. Memede fibrokistik kitlesi olanların kontrol grubuna göre D vitamin seviyesi daha düşük ve meme yoğunluğunun daha fazla olduğu tespit edildi. Meme yoğunluğu fazla olan grubun az olan gruba göre D vitamini seviyesinin daha düşük olduğu ve D vitamin seviyesi ile meme yoğunluğu arasında negatif korelasyon olduğu bulundu. Sonuç: Çalışmamızda memesinde fibrokistik kitlesi (BI-RADS2 ve BI-RADS3) olan kadınlarda, memesinde kitle olmayan kadınlara göre meme yoğunluğunun daha fazla ve D vitamini seviyesinin daha düşük olduğu bulundu.

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Section: Introductionmentioning

confidence: 99%

Kan 25-hidroksi D vitamini düzeyinin fibrokistik meme hastalığı ve meme yoğunluğu ile ilişkisi

Bolat

ERDOĞAN²

2022

Cukurova Medical Journal

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“…These cysts are typically located in the breast's upper outer quadrants along with the centre edges. When evaluated, the texture ranges from firm to many subcentimeter cysts [4] . Risk factors such as increased consumption of methylxanthiones from coffee, tea, cold drinks, and chocolate has been linked to the development of fibrocystadenosis.…”

Section: Introductionmentioning

confidence: 99%

Fibrocystadenosis with co-morbidity alleviated with homoeopathy: A case report

Kumari¹,

Billah²,

Saha³

2022

Int. J. Homoeopathic Sci.

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The most prevalent benign breast disease, known as fibrocystic breast disease, affects millions of women worldwide. The function, assessment, and treatment of this condition are all influenced by specific hormonal factors. The treatment used in modern medicine are Analgesics, metformin, prime rose oil and surgical removal, yet no permanent relief can be obtained. According to the homoeopathic literature, illnesses such as mastitis, tumor, and fibroadenoma have been effectively treated with homoeopathic medicine, and relatively few case reports concerning fibrocystadenosis have been published. Patient with fibroadenosis has a chance to develop certain co-morbidities like Pcos, fatty liver, etc. A study conducted by Ilknugur Inegol Gumus et al. discovered a statistically significant link between PCOS and fibrocystic breast disease 1 . The case presented here concerns fibrocystadenosis in a 27-year-old female who was treated with individualised homoeopathic therapy and had no recurrence after a year. Bryonia was administered as a constitutional remedy following Repertorisation and based on the totality of symptoms. Before and after cyst resolution, investigatory techniques such as mammography and ultrasonography were performed. Since the case shows the disappearance of fibrocystic changes in the left breast and all other general complaints are better so we can conclude the patient is on the path to cure. As the fibrocystic changes in right breast is still there, further treatment and follow-ups will show the final result. Increased long-term efficacy data are required to develop a more efficient cure for fibrocystadenosis.

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Assessment of the Cytokine-Producing Resource of Tumor Biopsy Samples from Patients with Invasive Carcinoma of No Special Type and with Non-Malignant Breast Diseases

Cited by 2 publications

References 20 publications

Kan 25-hidroksi D vitamini düzeyinin fibrokistik meme hastalığı ve meme yoğunluğu ile ilişkisi

Kan 25-hidroksi D vitamini düzeyinin fibrokistik meme hastalığı ve meme yoğunluğu ile ilişkisi

Fibrocystadenosis with co-morbidity alleviated with homoeopathy: A case report

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