Assessment of the haematological indices of albino rats fed diets supplemented with jackfruit bulb, seed or a blend of bulb and seed

Agiang, Margaret Akpana; Dongo, Bright Sunday; Williams, Ima O.; Utu-Baku, Ashang Bonny

doi:10.4314/ijbcs.v11i1.31

Cited by 6 publications

(6 citation statements)

References 18 publications

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“…The size of the cells may be normal (normocytic), below normal (microcytic) and above normal (macrocytic). This is comparable to what is experienced in iron deficiency anemia (Agiang et al, 2017).…”

Section: Discussionsupporting

confidence: 80%

“…High red cell distribution width (RDW) is an indication of nutrient deficiency particularly iron, folate and vitamin B12, can also show macrocytic anemia (Agiang et al, 2017). In the study, the experimental group that was supplemented with fructose/lard had a significant increase (p < 0.008) in RDW compared to the groups that were supplemented with ground chia seeds/extract only.…”

Section: Discussionmentioning

confidence: 87%

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Effect of chia seeds (<i>Salvia hispanica</i>) on postprandial glycaemia, body weight and hematological parameters in rats fed a high fat and fructose diet

Mihafu¹,

Kiage²,

Kimang'a³

et al. 2020

Int. J. Bio. Chem. Sci

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Chia seeds (Salvia hispanica) are currently consumed by varied populations as superfoods due to their protective, functional and antioxidant properties. The aim of this study was to determine the effect of ground chia seeds/extracts on postprandial glycaemia, body weight, hematological parameters and cellular morphology in rats. Twenty male Wistar rats were assigned into three experimental groups and a control (n =5). Each experimental group received 10 g/20 g fructose/lard. Additionally, 90 g rat pellet was fed to group 1 and 3 which was supplemented with 20 g chia seed extract, group 2 received ground chia seeds only. Control group received 90 g rat pellet only for 28 days. The results on body weight changes indicated a gradual increase in body weight of chia seeds/extract fed rats as compared to fructose/lard group. There was an increase in postprandial blood glucose levels in group 1 from week I to IV contrary to groups supplemented with chia seeds/extract. Complete blood counts showed a significant increase (p = 0.008) in mean corpuscular hemoglobin concentration, basophils (p = 0.035), platelets (p = 0.025) and red cell distribution width (p = 0.008) in experimental groups compared to control. These results pinpoint the benefits of chia seeds.Keywords: Blood composition, functional food, glucose concentration, metabolic diseases, omega-3 fatty acids

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Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 87%

Effect of chia seeds (<i>Salvia hispanica</i>) on postprandial glycaemia, body weight and hematological parameters in rats fed a high fat and fructose diet

Mihafu¹,

Kiage²,

Kimang'a³

et al. 2020

Int. J. Bio. Chem. Sci

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“…The body cannot produce pyridoxine (Vitamin B 6 ), one of the essential amino acids; hence it must be consumed through diet in order to satisfy daily requirements. It stimulates the metabolism of unsaturated fatty acids and protides that are side chains of amino acids (Agiang et al., 2017). This tea may thus be regarded as an excellent source of vitamin B 6 based on the RDA and the level of vitamin B6 found in the optimized tea examined in this study.…”

Section: Resultsmentioning

confidence: 99%

Quantification of phytochemicals, and compounds’ identification in functional tea from Ficus capensis and Justicia secunda

Uchegbu

Fasuan²,

Onuoha

2023

Journal of Food Science

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This work evaluated the development of beverage from Ficus capensis and Justicia secunda leaves composite using response surface methodology three-level factorial design gas chromatography-mass spectrophotometry. Fresh leaves of F. capensis and J. secunda were processed into tea. The results indicated the optimal extracts blends of 48% of F. capensis and 52% of J. secunda. The iron content was 489.11 mg/g; flavonoid content, 83.64 mg QE/100 g; vitamin C content, 1003.14 mg/100 g; and pyridoxine content, 357.31 mg/100 g. Alkaloid profile showed tetrahydrorhombiofoline (35%), columbamine (20.10%), laudanosine (11.50%), salsoline (8.22%), methylcobalamin (7.98%), quinine (5.89%), and quinidine (3.21%). Other phytocompounds with bioactive characteristics include 11-octadecenoic acid, methyl ester (32.43 g/100 g); hexadecanoic acid, methyl ester (16.69 g/100 g); 9,12-octadecadienoic acid (Z,Z)-, methyl ester (12.81 g/100 g); (E)-9-octadecenoic acid, ethyl ester (9.71 g/100 g); hexadecanoic acid, ethyl ester (5.86 g/100 g); methyl stearate (4.62); linoleic acid, ethyl ester (4.62 g/100 g), octadecanoic acid, ethyl ester (1.84 g/100 g); and octasiloxane,

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“…Red blood cell and hemoglobin function in the efficient transport of oxygen into and carbon dioxide out of, the body and in concert with PCV (the percentage of RBC in blood) indicates oxygencarbon dioxide balance status Oyedeji and Bolarinwa, 2013;Ugwuene, 2011). Furthermore, although non-significant influence on rats' hemoglobin and RBC levels but slight reduction in packed cell volume (PCV) concentration, were interpreted as absence of adverse effect on the rats' hematological properties (Iwueke, et al, 2018); Agiang, et al (2017) associated possession of some anti-anemic properties following improved/elevated RBC, Hb and PCV. Thus, the significant elevation in the levels of RBC, HB and PCV of the rats following exposure to bitter leaf stem extract as reported herein could be indicating improved gaseous (oxygen and carbon dioxide) transport leading to favorable oxygen -carbon dioxide balance, and improved anti-anemic properties in the rats.…”

Section: Resultsmentioning

confidence: 99%

Ethanolic Extract of Ground Vernonia Amygdalina Stem Exhibited Potent Antibacterial Activity and Improved Hematological Bio-Functional Parameters in Normal and Monosodium Glutamate-Intoxicated Rats

Egbuonu¹,

Amadi²

2021

jasem

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Herein, Vernonia amygdalina stem ethanolic extract, VASEE, was elucidated for its antibacterial activity in vitro by disk-diffusion technique and, in vivo effect on some hematological parameters of normal and monosodium glutamate, MSG-intoxicated rats. For in vivo study, 20 male albino rats assigned into five groups (A, B, C, D, and E) were, for 14 days, respectively administered MSG (8000 mg/kg body weight, bw), VASEE (200 mg/kg bw), Control (Vital feed and tap water), MSG (8000 mg/kg bw + VASEE, 200 mg/kg bw), and MSG (8000 mg/kg bw + VASEE, 400 mg/kg bw). In vitro, the VASEE-related activity against the tested bacterial pathogens was significant (P < 0.05), dose dependent and comparable to that by the standard antibacterial drug, Ciprofloxacin. In vivo, VASEE compared to control and MSG groups improved (P < 0.05) and, notably at the highest tested dose modulated the monosodium glutamate intoxication-related effect on, the studied hematology of rats. Thus, VASEE exhibited potent activity against the tested bacterial pathogens, improved, and potentially modulated MSG-intoxication-related effect on, the rats’ hematological functions. The study underscored a promising antibacterial application of the extract of hitherto wasted bitter leaf stem that could offer novel therapeutic benefits on the hematology of especially MSG-intoxicated rats, warranting further studies. Keywords: Hematology, intoxication, bitter leaf stem, packed cell volume, Red blood cell

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Assessment of the haematological indices of albino rats fed diets supplemented with jackfruit bulb, seed or a blend of bulb and seed

Cited by 6 publications

References 18 publications

Effect of chia seeds (<i>Salvia hispanica</i>) on postprandial glycaemia, body weight and hematological parameters in rats fed a high fat and fructose diet

Effect of chia seeds (<i>Salvia hispanica</i>) on postprandial glycaemia, body weight and hematological parameters in rats fed a high fat and fructose diet

Quantification of phytochemicals, and compounds’ identification in functional tea from Ficus capensis and Justicia secunda

Ethanolic Extract of Ground Vernonia Amygdalina Stem Exhibited Potent Antibacterial Activity and Improved Hematological Bio-Functional Parameters in Normal and Monosodium Glutamate-Intoxicated Rats

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