Background: In 90% of cases, the main cause of acute cholecystitis is gallbladder stones. The majority of Saudis are still unaware about Put, and there aren't enough papers in Saudi Arabia about gallstone disease knowledge. The aim of our study is to assess the awareness and knowledge of the general population of Saudi Arabia towards gallbladder stones and its risk factors. Methodology: In Saudi Arabia, an observational cross-sectional questionnaire study was done. The period runs from January 2020 through September 2021. The total number of participants in the study was 1540 Saudis. Data was collected using structured self-administered questionnaires as a study method. Data was input into excel, and then analyzed using the SPSS program. Results: There were 1540 participants in the study, with 65% of them being girls and 34.9% being males. Between the ages of 20 and 30, 47.9% of the population is between the ages of 20 and 30. Gallstones are known by 88.7% of the people in the study. A positive history of gallstones was reported by 39.9% of individuals, either directly or in a family member. Gallstones were found to cause stomach discomfort in 76.6% of cases, fever in 21.7%, pale skin in 36.7% of cases, jaundice in 36.7% of cases, exhaustion in 41.9% of cases, nausea in 40.1% of cases. Conclusion: There was a strong relationship between participants' awareness of gallbladder stones and their age, gender, and educational level. To promote awareness of the disorders, future health awareness programs and conferences are proposed.