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Background and Amis: Gallstone disease is one of the most common worldwide biliary tract disease in which the both genetic and environmental factors have roles in its pathogenesis. shortage of knowledge on gallstone disease contributed to poor dealing with cholelithiasis patients. Thus, the main aims of this study to assess the women knowledge regarding the cholelithiasis disease. Method:A cross-sectional study was conducted on 60 inpatient of gallstone disease in Azadi and emergency teaching hospital in Duhok city, A set of questionnaires were used to collect the data about their socio-demographic, and knowledge around gallstone disease by interviewer with selfadministered. A descriptive and inferential statistical analysis used to analyze the data. Result:The majority of the participants were (66%) their age 42.03 ± 12.63 within 42 years old, while the lowest ratio (13.3 %) was <29 years old. more than half (66.67%) of women had poor knowledge, (33.33%) had good knowledge about gallstone disease. However, the results indicated there was correlation between mother knowledge significantly with age (p-value 0.001).Therefore, the level of education had significant relationship to awareness of women toward gallstone disease. Conclusion:In this study, the results indicated that lack of knowledge was the major contributing factor for causing gallstone because due lack of awareness women were do not know the way of decreasing risk factor of gallstone disease.

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