Assessment of Thyroid Function During Pregnancy

Chan, Vivian; Paraskevaides, C. A.; Hale, J.

doi:10.1111/j.1471-0528.1975.tb02211.x

Cited by 21 publications

(7 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, it is well known that T3 and T4 steadily increase during the first trimester and remain at high levels thereafter (Chan et al, 1975;Yamamoto et al, 1979;Skjoldebrand et al, 1982).…”

Section: Discussionmentioning

confidence: 99%

Serum thyroglobulin concentration in normal pregnancy.

et al. 1984

View full text Add to dashboard Cite

We measured the levels of serum thyroglobulin (Tg) in 52 pregnant females at various stages and compared them with those of 15 age-matched nonpregnant females. Serum Tg was measured by a solid-phase immunoradiometric assay. In pregnant females, mean serum Tg levels at the first, second, early third, and late third trimesters were 8.4 (range; 1.3-18.0), 9.2 (1.7-25.6), 10.1 (1.8-22.8), and 12.1ng/ml (5.3-25.2), respectively. The statistical comparison was made after logarithmic transformation of the data. The mean value only at the late third trimester was significantly higher than that of controls (mean; 6.0ng/ml, range; 1.5-23.6), but each value was within the normal range. Although serum Tg levels have been reported to be high at the end of pregnancy, our results indicate that the Tg levels in females could be clinically interpreted without regard to the coexistence of pregnancy.

show abstract

Section: Discussionmentioning

confidence: 99%

Serum thyroglobulin concentration in normal pregnancy.

et al. 1984

View full text Add to dashboard Cite

show abstract

“…Serum total T3, total T4, TSH and PRL concentrations were measured by specific RIA as previously described (Chan et al, 1975a;Chan et al, 1975b;Nye et al, 1975;McNeilly & Hagen, 1974). Purified human PRL was used for iodiAation and the MRC 75/504 was used as standard.…”

Section: Methodsmentioning

confidence: 99%

Effects of Heroin Addiction on Thyrotrophin, Thyroid Hormones and Prolactin Secretion in Men

Chan

Wang

Yeung

1979

Clinical Endocrinology

Self Cite

View full text Add to dashboard Cite

Pituitary-thyroid function in male heroin addicts and addicts after abstinence (ex-addicts) was studied and compared with that of healthy euthyroid men. In heroin addicts the increases in circulating total thyroxine and triiodothyronine levels were accompanied by an increase in the thyroid hormone uptake test. These changes may reflect a quantitative increase in thyroxine binding globulin. Reverse triiodothyronine concentrations in heroin addicts were normal. The thyrotrophin-releasing hormone elicited a diminished thyrotrophin response in heroin addicts which was significantly different from that in control subjects and ex-addicts. An elevation of serum prolactin was noted in heroin addicts, while ex-addicts had normal levels. Gradual recovery of pituitary-thyroid function occurred after heroin withdrawal.

show abstract

“…This may be due to an increased level of hormonal activity in females. For example, circulating thyroid-stimulating hormone levels are elevated in pregnancy [Chan et al, 1975], and this hormone plays a role in nonmedullary thyroid cancer in experimental animals [Lindsay et al, 1966]. Women who have had at least one child were shown to be twice as likely to develop thyroid cancer as nulliparous women [Miller et al, 1980].…”

Section: Discussionmentioning

confidence: 99%

Family with Graves disease, multinodular goiter, nonmedullary thyroid carcinoma, and alveolar rhabdomyosarcoma

et al. 1997

View full text Add to dashboard Cite

Benign thyroid disease is a risk factor for nonmedullary thyroid carcinoma [Houlston and Stratton: Q J Med 88:685-693, 1995]. We report on a family with 7 members with benign and/or malignant thyroid neoplasia; one affected female died of a paravertebral alveolar rhabdomyosarcoma at age 20. The occurrence of thyroid nodular hyperplasia, nonmedullary thyroid cancer, and rhabdomyosarcoma in the same family may be due to chance, common environmental factors, or, most likely, genetic predisposition.

show abstract

Assessment of Thyroid Function During Pregnancy

Cited by 21 publications

References 19 publications

Serum thyroglobulin concentration in normal pregnancy.

Serum thyroglobulin concentration in normal pregnancy.

Effects of Heroin Addiction on Thyrotrophin, Thyroid Hormones and Prolactin Secretion in Men

Family with Graves disease, multinodular goiter, nonmedullary thyroid carcinoma, and alveolar rhabdomyosarcoma

Contact Info

Product

Resources

About