Assessment the Efficacy of Arthrocentesis with Corticosteroid and Arthrocentesis with Sodium Hyaluronate in Treatment Temporomandibular Joint Disorders: A Comparative Study

Abstract

Background: Temporomandibular joint disorders (TMD) refer to a group of heterogeneous pain and dysfunction conditions involving the masticatory system, reducing life quality of the sufferers. Aim of study: The aim of the study was to evaluate the effectiveness of arthrocentesis with corticosteroid (betamethasone) injection and with sodium hyaluronate injection in treatment temporomandibular joint disorders, in conjunction with a stabilizing splint, for improving function and reducing pain, for preventing further deterioration of the TMJ dysfunction, to maintain improvements over time, and compare between them. Patients and methods: Fifty -four patients with TMJ disorders with age limit between 18 and 55 years of age, 9 males and 36 females, were enrolled in this study. Patients were randomly divided into two groups, in which one group received arthrocentesis with intra-articular corticosteroid (betamethasone) injection (1 ml), and another group received arthrocentesis with intra-articular sodium hyaluronate injection (1 ml) in superior joint space ,in single puncture. Patients were followed at regular interval of 7th day, one month, 3, 6, 9, 12 months (follow up) after last injection. Results: The mean age of patients was 8.873 ± 34.112 years in Group-A treat by betamethasone and10.973± 33.27 years in Group-A treat by sodium hyaluronate (ranged from 18.2 to 55.0 years).

Current Clinical Research Directions on Temporomandibular Joint Intra-Articular Injections: A Mapping Review

“…There is a steady upward trend in the number of primary studies on HA published in subsequent years. The primacy of HA from 2021 seems to be threatened by centrifuged blood products, but this group of substances is heterogeneous and cannot be compared to HA in terms of effectiveness as a whole [18,19,22,25,38,43,49,51,54,[58][59][60]63,68,70,71,74,75,78,80,80,82,86,88,89,[91][92][93]95,[98][99][100][101][102]105,106,110,[113][114][115][116][117]120,121,124,126,127,129,130,…”

“…CSs are definitely the best studied among them. After HA and PRP, CSs were the third most frequently reported injectables group in 2017-2022 (8 systematic reviews, 10 randomized trials, and 8 other trials) [19,25,38,39,41,45,47,47,49,51,54,62,75,86,121,125,127,134,135,137,140,156,164,166,171]. Nevertheless, since 2020, the number of primary studies on intra-articular injection of CSs has clearly decreased.…”