Assessments of antioxidant, antilipid peroxidation, and In-vitro safety of Derris scandens vine extracts from Southern Thailand

Nooin, Rawiwan; Pitchakarn, Pornsiri; Kanchai, Chaturong; Jaikang, Churdsak

doi:10.4103/pr.pr_141_18

Phcog Res

2019

DOI: 10.4103/pr.pr_141_18

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Assessments of antioxidant, antilipid peroxidation, and In-vitro safety of Derris scandens vine extracts from Southern Thailand

Rawiwan Nooin

Pornsiri Pitchakarn

Chaturong Kanchai

et al.

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Cited by 4 publications

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“…antioxidant, 10 antifungal, 11 antidiabetic, 12-14 and antimicrobial, 15 of T. grandis (Lamiaceae), antioxidant, anti-lipid peroxidation, 16 musculoskeletal pain treatment, 17 hepatocellular carcinoma cell line. 18 of D. scandens (Leguminosae). Whereas S. chinensis (Leguminosae) had antioxidant.…”

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Acute Toxicity of Aqueous Extract of a Diabetic Folklore Recipe Thai Traditional Medicine in Rats

2023

TJNPR

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Some biological activities for each component herb of recipe have been previously studied such as:the antioxidant, anti-inflammatory and antimicrobial activity 3-4 of C. paniculatum (Lamiaceae), antioxidant, antidiabetic activity by α-amylase and α-glucosidase inhibition, 5 and antihypercholesterol activity 6 of A. flava (Menispermaceae), antioxidant, antibacterial, cytotoxic, 7 of S. multifloraa (Euphorbiaceae), hepatoprotective, antihyperglycemic and antidiabetic, 8 antiinflammatory, 9 of D. pentandra (Loranthaceae). antioxidant, 10 antifungal, 11 antidiabetic, 12-14 and antimicrobial, 15 of T. grandis (Lamiaceae), antioxidant, anti-lipid peroxidation, 16 musculoskeletal pain treatment, 17 hepatocellular carcinoma cell line. 18 of D. scandens (Leguminosae). Whereas S. chinensis (Leguminosae) had antioxidant. [19][20][21] However, the combination of plants in the recipe, on the other hand, has a lot of literature to analyze on biological activity. Furthermore, the recipe is still widely used as an ethno-pharmaceutical to treat a variety of diseases, and there has not been a scientific report on its safety and toxicity. As a result, the purpose of this study is to use the OECD 420 guidelines to evaluate the oral acute toxicity of an aqueous extract of a diabetic folklore recipe from Thai traditional medicine in male and female rats. Materials and Methods Sample collectionThe seven plants in the recipe were collected from a local cultivation area in Maha Sarakham Province, Northeastern Thailand in May-June 2020. The specimens were identified by Asst. prof. Piyaphong Yupparach and deposited at the Faculty of Medicine, Mahasarakham

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Acute Toxicity of Aqueous Extract of a Diabetic Folklore Recipe Thai Traditional Medicine in Rats

2023

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Sesbania javanica Miq leaf extracts increase Balb/c 3T3 fibroblast cell migration

Herabutya,

Lekpeth,

Posamton

et al. 2024

Braz. J. Biol.

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Sesbania javanica Miq. is widely distributed in canals throughout Thailand and its flowers are commonly consumed in Thailand. Sesbania javanica floral extracts have previously been demonstrated to have antimutagenic activity, but information on the bioactivity and beneficial properties of other plant parts, such as the leaf, remains limited. In this study, the induction of cell proliferation and wound-healing activity of DMSO extracts from flowers and leaves of S. javanica was evaluated. A high concentration (1:25 and 1:50 dilutions) of all extracts was cytotoxic to Balb/c 3T3 fibroblast cells. A low concentration (1:500 and 1:1000 dilutions) of extracts A, B, and C (extracted from leaves) significantly promoted cell viability after treatment of the fibroblast cells for 24 or 48 h. The 1:500 and 1:1000 dilutions of extracts B and C were selected for a scratch assay to assess their wound-healing activity and significantly decreased the wound area after treatment for 24 h. These findings provide evidence that leaf extracts from S. javanica have potential utility for the treatment of wounds.

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Phytochemical Screening, Antioxidant and Sperm Viability of Nelumbo nucifera Petal Extracts

Laoung-on

Jaikang

Saenphet

et al. 2021

Plants

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Sacred lotus (Nelumbo nucifera Gaertn.; N. nucifera) is a common ingredient in traditional medicine and Thai recipes. Its petal is an agricultural waste from stamen production. There are limitations in the used and pharmacological data of the petals resulting in more petals waste. The aims of this study were to investigate the phytochemical contents, antioxidant activity, and potential effects on sperm viability of aqueous (NAE) and ethanolic extracts (NEE) of both red and white N. nucifera petals. The white NAE had the highest total phenolics content, total tannins content and maximal antioxidant activity. The white NEE had the highest concentration of total flavonoids. Quercetin was a major flavonoid and was found in the aqueous extracts. Both red and white of NAE in the range of 0.22 to 1.76 mg/mL increased sperm viability. The white NAE was prominent in phytochemical content, antioxidant activity, and both red and white NAE effectively increased rat sperm viability in the in vitro model. The white NAE enhanced sperm viability by decreasing oxidative stress. It might be suggested that the N. nucifera petals have benefits for sperm viability health promotion and may increase the economic value of agricultural waste.

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Assessments of antioxidant, antilipid peroxidation, and In-vitro safety of Derris scandens vine extracts from Southern Thailand

Cited by 4 publications

References 3 publications

Acute Toxicity of Aqueous Extract of a Diabetic Folklore Recipe Thai Traditional Medicine in Rats

Acute Toxicity of Aqueous Extract of a Diabetic Folklore Recipe Thai Traditional Medicine in Rats

Sesbania javanica Miq leaf extracts increase Balb/c 3T3 fibroblast cell migration

Phytochemical Screening, Antioxidant and Sperm Viability of Nelumbo nucifera Petal Extracts

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