Assisted Reproductive Techniques in Latin America: The Latin American Registry,
            2015

Zegers‐Hochschild, Fernando; Schwarze, Juan Enrique; Crosby, Javier; Musri, Carolina; Urbina, María Teresa

doi:10.5935/1518-0557.20190021

Cited by 5 publications

(4 citation statements)

References 6 publications

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“…The method of collecting data in 2016 resembles previous years (Zegers-Hochschild et al ., 2018; 2019), making results comparable. Definitions used refer to the latest publication of the International glossary on Infertility and Fertility Care (Zegers-Hochschild et al ., 2017).…”

Section: Methodsmentioning

confidence: 99%

Assisted reproductive techniques in Latin America: The Latin American registry, 2016

Zegers‐Hochschild

Schwarze

Crosby

et al. 2019

JBRA Assisted Reproduction

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Research question: What was the utilization, effectiveness and perinatal outcome of assisted reproductive technologies (ART) performed in Latin America during 2016 Design: Retrospective collection of multinational data on ART performed in 178 institutions from 15 Latin American countries. Results: We are reporting 85,474 initiated cycles, 15,070 deliveries and 18,182 babies born in this period. Of all fresh autologous IVF/ICSI cycles, 40.9% were performed in women aged 35–39 years, and 31.1% in women aged ≥40 years. After removing freeze-all cycles, delivery rate per oocyte retrieval was 20.31% for ICSI and 21.85% for IVF. Fresh single embryo transfer including all age categories represented 22.96%, with a 15.35% delivery rate per transfer. Double embryo transfer represented 61.58% of transfers, with a 27.62% delivery rate per transfer. Multiple births included 18.12% twins and 0.55% triplets and higher. In oocyte donation, delivery rate per transfer was 32.89%, with a twin and triplet rate of 23.48% and 0.73%, respectively. Overall, preterm deliveries reached 17.11% in singletons, 65.69% in twins and 95.51% in triplets. Perinatal mortality was 8.0 ‰ in singletons, 19.0 ‰ in twins, and 62.3 ‰ in high-order multiples. Conclusions: The number of initiated cycles continues to increase. Compared with previous years, the number of embryos transferred decreased while the proportion of single embryo transfers increased with a drop in multiple births. It is mandatory to stimulate health care providers and consumers to continue in this trend.

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Section: Methodsmentioning

confidence: 99%

Assisted reproductive techniques in Latin America: The Latin American registry, 2016

Zegers‐Hochschild

Schwarze

Crosby

et al. 2019

JBRA Assisted Reproduction

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“…The Brazilian Society of Assisted Reproduction (SBRA) listed 133 associated centers in its website in 2015, but it is not known which had their own lab. REDLARA encompassed 58 registered clinics in Brazil in 2015(Zegers-Hochschild et al, 20182019). The SisEmbrio registry, established in 2008, only includes clinics that perform ART, adding up to 141 registers in 2015.…”

Section: Methodsmentioning

confidence: 99%

Assisted Reproductive Technologies in Brazil: characterization of centers and profiles from patients treated

Machin¹,

Mendosa²,

Augusto³

et al. 2020

JBRA Assisted Reproduction

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Objective: The aim of this study was to analyze the application of assisted reproductive technologies (ART) in Brazil from the active clinics and the population served considering the changes in the last resolutions of the Federal Council of Medicine (CFM), which enabled the use of the techniques for anyone, regardless of their health insurance system, gender or marital status. Methods: This paper was based on the analysis from the "Reproductive Technologies and (in) fertility study: regulation, market and rights". We used quantitative and qualitative methodologies. In this paper, we used the empirical data produced in the quantitative study. The quantitative online survey was carried out in 2016-2018, answered by 81 fertility clinics in Brazil about their performance in 2015-2016. We opted to use the REDCap Program, a web-based application for the construction and management of online surveys and databases. The questionnaire addressed the characteristics of services, practices performed, population served and existing forms of funding. Results: The questionnaires returned corresponded to 63.1% of the clinics in the southeast region. ART is mainly offered by 90.1% private clinics. We report that 63.8% of establishments have up to 20 employees; 44.5% have been in operation between 11 and 20 years. 85.1% of the clinics reported having treated non-Brazilian residents. Conclusions: There has been a significant increase in the provision of ART in Brazil. Access remains thoroughly dependent on its own financial resources. The new CFM resolutions have shifted from the prevailing concept of "health care" to "assisting with new family configurations".

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“…This approach extends to cases involving premature ovarian failure, diminished ovarian function, recurrent pregnancy loss, maternal genetic abnormalities, and unsuccessful in vitro fertilization (IVF) attempts. The utilization of donor eggs has become crucial in addressing challenges related to insufficient egg quantity or quality, reflecting a significant portion of ART cycles globally, such as 22% in Latin America [1], approximately 10% in the USA [2], and a comparable percentage in Europe [3]. The increasing reliance on ART over the past decade, with more than a doubling of usage in the USA [2], underscores its importance in addressing infertility.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Repetitive Controlled Ovarian Stimulation (COS) Cycles on Oocyte Donors: Impact on Oocyte Quality and Viable Embryo Yield

Yarkiner,

Boynukalın,

Coban

2024

Reprod. Sci.

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The utilization of donor eggs has broadened the options for Assisted Reproductive Technology (ART) among women facing challenges with egg quantity or quality. Given that donors are typically selected from young and fertile individuals, In Vitro Fertilization with egg donation (IVF-ED) tends to exhibit higher rates of implantation, pregnancy, and live births compared to IVF with the woman's own eggs, especially for females over 35 years old. This has led to a projected increase in the demand for IVF-ED, surpassing the number of available donors. Consequently, many centers opt to use oocyte donors for multiple cycles. However, the correlation between repeated Controlled Ovarian Stimulation (COS) cycles and the performance of donors in terms of viable blastocyst stage embryo (VEC) or blastocyst embryo rate is not definitively established and remains of interest. This study aims to explore the preimplantation characteristics of embryo development and oocyte maturation status based on the number of donor COS cycles, employing a Generalized Linear Mixed Model (GLMM) framework. The study encompasses 1965 embryo transfer (ET) cycles involving 399 donors who underwent a minimum of two and a maximum of nine controlled ovarian hyperstimulation (COS) cycles. The findings indicate that, with the patient undergoing six or more cycles of ovarian stimulation, despite a 3.9% increase in both maturation and fertilization rates, there is a corresponding decrease of 4.5% in VEC rate and 4.7% in blastulation rates. In essence, an escalating number of donor COS cycles appears to be associated with a disadvantageous reduction in embryo quality.

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Assisted Reproductive Techniques in Latin America: The Latin American Registry, 2015

Cited by 5 publications

References 6 publications

Assisted reproductive techniques in Latin America: The Latin American registry, 2016

Assisted reproductive techniques in Latin America: The Latin American registry, 2016

Assisted Reproductive Technologies in Brazil: characterization of centers and profiles from patients treated

Assessment of Repetitive Controlled Ovarian Stimulation (COS) Cycles on Oocyte Donors: Impact on Oocyte Quality and Viable Embryo Yield

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