Objective:To investigate construct validity and test–retest reliability of the
parent-rated Hand-Use-at-Home questionnaire (HUH) in children with neonatal
brachial plexus palsy or unilateral cerebral palsy.Design and subjects:For this cross-sectional study, children with neonatal brachial plexus palsy
or unilateral cerebral palsy, aged 3–10 years, were eligible.Main measures:The HUH, Pediatric Outcome Data Collection Instrument Upper Extremity Scale
(neonatal brachial plexus palsy only), and Children’s Hand-Use Experience
Questionnaire (unilateral cerebral palsy only) were completed. The HUH was
completed twice in subgroups of both diagnoses. Lesion-extent (indication of
involved nerve rootlets in neonatal brachial plexus palsy as confirmed
during clinical observation and/or nerve surgery) and Manual Ability
Classification System levels (unilateral cerebral palsy) were obtained from
the medical records. Spearman correlation coefficients between the HUH and
all clinical variables, agreement, standard error of measurement, smallest
detectable change and intra-class correlation were calculated.Results:A total of 260 patients participated (neonatal brachial plexus palsy: 181),
of which 56 completed the second HUH (neonatal brachial plexus palsy: 16).
Median age was 6.9 years for children with neonatal brachial plexus palsy,
116 had C5-C6 lesions. Median age for children with unilateral cerebral
palsy was 6.4 years, 33 had Manual Ability Classification System Level II.
The HUH correlated moderately with lesion-extent
(rs =−0.5), Pediatric Outcome Data
Collection Instrument Upper Extremity Scale
(rs = 0.6) and Children’s Hand-Use Experience
Questionnaire (rs = 0.5) but weakly with Manual
Ability Classification System levels
(rs = −0.4). Test–retest reliability was
excellent (intra-class correlation2,1 = 0.89, standard error of
measurement = 0.599 and smallest detectable change = 1.66 logits) and
agreement was good (mean difference HUH1 − HUH2 = 0.06 logits).Conclusion:The HUH showed good construct validity and test–retest reliability in
children with neonatal brachial plexus palsy or unilateral cerebral
palsy.