Association between Blood Pressure and Birth Weight among Rural South African Children: Ellisras Longitudinal Study

Monyeki, Kotsedi Daniel; Kemper, Han C. G.; Mogale, A.; Hay, L.; Sekgala, Machoene Derrick; Mashiane, Tshephang M.J.; Monyeki, Suzan; Sebati, Betty

doi:10.3390/ijerph14090974

Cited by 10 publications

(22 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Preliminary Ellisras Longitudinal Study (ELS) results reported a high prevalence of under-nutrition amongst older children (7-10 years) compared to younger children [10,20]. Furthermore, Monyeki et al [21] reported the association between hypertension and under-nutrition amongst younger children whose birth weights were recorded while Mphekgwane et al [22] reported no significant association between hypertension and under-nutrition in younger ELS children (age 5-15 years). The aim of this study, therefore, was to determine the association between under-nutrition and hypertension among older Ellisras children and adolescents aged 9-17 years.…”

Section: Introductionmentioning

confidence: 99%

The Relationship between Under-Nutrition and Hypertension among Ellisras Children and Adolescents Aged 9 to 17 Years

Mphahlele

Monyeki

Dibakwane

et al. 2020

IJERPH

View full text Add to dashboard Cite

Background: Globally, under-nutrition and hypertension in children has been associated with the risk of developing cardiovascular disease (CVD) in adulthood. The main objective of this study was to investigate the relationship between under-nutrition and hypertension, furthermore, to determine the risk of developing hypertension due to under-nutrition. Methods: The study comprised of 1701 participants (874 boys and 827 girls) between the ages of 9 and 17 years old. All anthropometric and blood pressure measurements were taken according to standard procedures. Mid-upper arm circumference (MUAC), body mass index (BMI), upper arm fat area (UFA), total upper arm area (TUAA) and upper arm muscle area (UMA) of Ellisras children were compared with the National Health and Nutrition Examination Survey III reference population. The linear regression models were used to determine the relationship between under-nutrition with hypertension for unadjusted and then adjusted for age and gender. The logistic regression model was used to determine the risk of under-nutrition on developing hypertension for unadjusted and adjusted for age and gender. Results: There was a positive significant (p < 0.0001) association between all under-nutrition variables (MUAC, BMI, UFA, TUAA and UMA) and systolic blood pressure (SBP; beta ranges between 0.84 and 2.78), and diastolic blood pressure (DBP; beta ranges between 0.3 and 1.08 before adjusting and after adjusting for age and gender (SBP, beta ranges between 0.59 and 2.00 and DBP (beta ranges between 0.24 and 0.80. Conclusion: The prevalence of under-nutrition was high while the prevalence of hypertension was low in this study. The mean under-nutrition variables (BMI, UFA, UMA and MUAC) of Ellisras children were far lower compared to the NHANES III reference population. Hypertension was significantly associated with under-nutrition in this study.

show abstract

Section: Introductionmentioning

confidence: 99%

The Relationship between Under-Nutrition and Hypertension among Ellisras Children and Adolescents Aged 9 to 17 Years

Mphahlele

Monyeki

Dibakwane

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…Moreover, a sizeable Mendelian randomization analysis failed to detect an inverse relationship between birth weight and blood pressure [15]. Another similar study on birth weight and blood pressure in rural subjects also highlighted this issue [17].…”

Section: Introductionmentioning

confidence: 99%

“…However, the current research on the relationship between birth weight and blood pressure is partly controversial and even completely contradictory [15][16][17]. Lai C et al [16] found a U-shaped relationship between birth weight and blood pressure, especially SBP.…”

Section: Introductionmentioning

confidence: 99%

Birth weight influences differently on systolic and diastolic blood pressure in children and adolescents aged 8–15

2022

View full text Add to dashboard Cite

Aim Globally, hypertension is one of the main threats to public health and a significant risk factor predisposing individuals to various cardiovascular conditions. Hypertension in the young is particularly complex and challenging. Accumulating evidence has implicated that low birth weight is vital for elevated blood pressure, and birth weight was negatively correlated with blood pressure. However, fewer studies with conflicting results have addressed the associations between birth weight and blood pressure in children and adolescents, and there is no relevant research conducted in the NHANES population. The principal objective of this project was to investigate the relationship between birth weight and blood pressure in children and adolescents in NHANES. Methods A total of 7600 subjects aged 8 to15 were enrolled in the present study from the National Health and Nutrition Examination Survey (NHANES) 2007–2018. Outcome variables were systolic blood pressure(SBP) and diastolic blood pressure(DBP). Birth weight was regarded as an independent variable. EmpowerStats software and R (version 3.4.3) were performed to examine the association between birth weight and SBP or DBP. Results Birth weight was negatively correlated with SBP in the fully-adjusted model(β = -0.02, 95%CI: -0.04 to -0.04, p = 0.0013), especially in non-Hispanic White (β = -0.03, 95%CI: -0.06 to -0.00,p = 0.0446), aged between 13 to 15(β = -0.03, 95%CI: -0.04 to -0.01, p = 0.0027), and male individuals(β = -0.03, 95%CI: -0.05 to -0.01, p = 0.0027). However, there was no unidirectional association between birth weight and DBP in the fully adjusted model(β = -0.01, 95%CI: -0.03 to 0.02, p = 0.5668) and in sub-analysis. An inverted U-shaped and J-shaped relationship was uncovered between birth weight and DBP in those aged 13 or above and Mexican Americans, respectively. The inflection point calculated by a recursive algorithm of birth weight in these groups was all 105 oz. Conclusions The current study identified that birth weight was negatively related to SBP but not significantly related to DBP in children and adolescents aged 8 to 15, highlighting different potential mechanisms behind high SBP and high DBP in the young. However, an inverted U-shaped and J-shaped relationship between birth weight and DBP was observed, suggesting that targeted intervention measures should be taken for different groups of people rather than generalizations.

show abstract

“…Birth weight (BW) is considered a significant indicator for assessing fetal intrauterine growth, the nutritional condition and the health status of newborns, as well as predicting growth, developmental status, and health problems in adulthood [1][2][3]. In newborns with a normal weight, those with a low birth weight and macrosomia are related to higher morbidity and mortality [4][5][6], and low birth weight can result in poor mental development, risk of infection, and risk of developing cardiovascular disease later in life [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Association between maternal iron supplementation and newborn birth weight: a quantile regression analysis

Shi

Zhang

et al. 2021

Ital J Pediatr

View full text Add to dashboard Cite

Objective Our study aimed to explore the association between maternal iron supplementation and newborn birth weight (BW) in Shaanxi Province using quantile regression (QR). Method The data used in this study were derived from a large cross-sectional survey of a population in Shaanxi Province, Northwest China. A total of 28,209 women and their infants were selected using a stratified multistage random sampling method. The effect of iron supplementation on the newborn BW was assessed by a multiple linear regression model and QR. Results A total of 5.15% of the women took iron supplements during pregnancy. Multiple linear regression showed that the iron supplementation during pregnancy had positive effects on the BW, with an average increase of 43.07 g (β = 43.07, t = 3.55, and p < 0.001). The QR showed that the iron supplementation during pregnancy was associated with an increased newborn BW from very low to higher percentiles (quantiles: 0 ~ 0.40), with the β ranging from 136.51 to 43.86. As the percentiles of the BW increased, the neonatal BW gain gradually declined in the iron supplementation group compared with the group that did not receive iron supplementation (quantiles: 0 ~ 0.40, with the β ranging from 136.51 to 43.86). Iron supplementation was more effective among women who suffered from anemia during pregnancy (β = 45.84, t = 2.05, and p = 0.04; quantiles: 0 ~ 0.15, 0.30, 0.80, with β ranging from 150.00 to 39.29) than it was in any other group (β = 38.18, t = 2.62, and p = 0.009; quantiles: 0 ~ 0.15, with β ranging from 133.33 to 28.32). Conclusions Iron supplementation during pregnancy is associated with an increased newborn BW, and the effect was more obvious in the newborns with the lower BW and newborns whose mothers suffered from anemia during pregnancy.

show abstract

Association between Blood Pressure and Birth Weight among Rural South African Children: Ellisras Longitudinal Study

Cited by 10 publications

References 38 publications

The Relationship between Under-Nutrition and Hypertension among Ellisras Children and Adolescents Aged 9 to 17 Years

The Relationship between Under-Nutrition and Hypertension among Ellisras Children and Adolescents Aged 9 to 17 Years

Birth weight influences differently on systolic and diastolic blood pressure in children and adolescents aged 8–15

Association between maternal iron supplementation and newborn birth weight: a quantile regression analysis

Contact Info

Product

Resources

About