Association Between Dietary Pattern and Serum C-Reactive Protein in Japanese Men and Women

Abstract

BackgroundDietary pattern may influence the risks of cardiovascular disease, atherosclerosis, type 2 diabetes, and metabolic syndrome through its effects on inflammation. We evaluated the association between dietary pattern and serum high-sensitivity C-reactive protein (hs-CRP) in a Japanese population.MethodsIn this cross-sectional analysis, we used baseline data from 3905 men and 5640 women (age 40–69 years) who participated in a population-based cohort study between November 2005 and December 2007. Participants with possible inflammation-related diseases, current analgesic use, high hs-CRP levels (≥3000 ng/mL) or extreme dietary energy intake were excluded. We used 46 items from a validated short food frequency questionnaire and examined major dietary patterns by factor analysis.ResultsWe identified 5 dietary patterns: healthy (high in vegetables and fruit), Western (high in meat and fried foods), seafood (high in shellfish, squid, fish, etc.), bread (high in bread and low in rice), and dessert (high in confections and fruit). After adjustment for age, alcohol use, smoking, physical activity, and body mass index, hs-CRP levels in men were inversely associated with the healthy, bread, and dessert patterns (P-trend: 0.01, 0.06, and <0.01, respectively) and positively associated with the seafood pattern (P-trend = 0.02). In women, hs-CRP levels were inversely associated with the healthy pattern (P-trend = 0.06) and positively associated with the Western pattern (P-trend = 0.06).ConclusionsThe healthy dietary pattern may be associated with suppressed inflammation in Japanese men and women, independently of body mass index and other factors. The sex-specific associations of hs-CRP with other dietary patterns (eg, the seafood pattern) require further study.

Associations of dietary patterns with metabolic syndrome and insulin resistance: a cross-sectional study in a Japanese population

“…Also, the four dietary patterns extracted in our study explained only 33% of the total variance. However, the dietary patterns identified in our study and the proportion of variance explained were similar to those reported for other populations in Japan (15,19,27,28). Third, except for staple foods, information on food consumption was limited to only frequency, and no information on the portion size was collected.…”

“…The bread and dairy products pattern was analogous to the Westernized breakfast pattern reported by Akter et al (15,16) except for the lower factor loadings for Western-type and Japanese confectioneries, and the bread pattern reported from another study group of the J-MICC study (27), except for somewhat higher factor loadings for milk and yogurt, and a negative factor loading for shellfish. The seafood pattern identified in this study was similar to that reported by Nanri et al (27), despite somewhat lower factor loadings for fish and small fish with bones, as well as that reported for another Japanese population by us (29) except for alcoholic beverages (which were not included in the present analysis of dietary patterns). Prudent diet pattern scores were correlated with a lower prevalence of reduced serum HDL cholesterol and high blood pressure in our study.…”

“…Prudent/healthy diet and high fat/Western diet patterns have been consistently identified in previous studies performed in various countries, including Japan (19,20,27,28), Korea (17), Iran (7), and the U.S. (8,9,13). The bread and dairy products pattern was analogous to the Westernized breakfast pattern reported by Akter et al (15,16) except for the lower factor loadings for Western-type and Japanese confectioneries, and the bread pattern reported from another study group of the J-MICC study (27), except for somewhat higher factor loadings for milk and yogurt, and a negative factor loading for shellfish. The seafood pattern identified in this study was similar to that reported by Nanri et al (27), despite somewhat lower factor loadings for fish and small fish with bones, as well as that reported for another Japanese population by us (29) except for alcoholic beverages (which were not included in the present analysis of dietary patterns).…”

Adherence to the 2006 American Heart Association Diet and Lifestyle Recommendations for cardiovascular disease risk reduction is associated with bone health in older Puerto Ricans

“…Most recently, adherence to a Mediterranean diet was associated with a 7% lower hip fracture incidence in a European cohort (31). Similarly, in a cohort of Japanese men and women, greater adherence to a healthy dietary pattern characterized by fruit and vegetables was associated with lower serum CRP (32). In addition to markers of systemic…”

Relação entre Valores de Leucócitos e PCR-US Com o Consumo Alimentar Habitual de Vitamina com Ação Antioxidante em Idosos

“…Assim, os leucócitos e seus subconjuntos não são apenas marcadores inflamatórios, mas também desempenham importantes papéis na inflamação devido aos seus efeitos ou funções que coletivamente representam um importante mecanismo de imunidade inata 9 . Ainda no que se refere a marcadores inflamatórios, no caso, à proteína C reativa ultrasensível (PCR-us), vários estudiosos constataram que indivíduos com padrões alimentares saudáveis com destaque para o consumo de frutas e vegetais apresentaram baixos valores de PCR-us 10 , também em estudos transversais há relatos de que indivíduos com maior ingestão de vitamina E, carotenoides e vitamina C apresentaram diminuição da inflamação de baixo grau 11 de outro estudo, houve relação inversa entre a ingestão de vitamina E e PCR-us 12 . Considerando a inexistência de estudos na literatura consultada sobre a relação entre os valores de leucócitos e PCR-us com o consumo alimentar habitual de vitamina com ação antioxidante em idosos, este estudo é pertinente, e teve como objetivo avaliar a relação entre os valores de leucócitos e PCR-us com o consumo alimentar habitual de vitamina A, β-caroteno, vitamina C e vitamina E; uma vez confirmada essa relação, a ingestão dessas vitaminas, seria ainda mais justificada, considerando-se também, a sua importância na adequação dos valores de leucócitos.…”