Association between early pregnancy vitamin D status and changes in serum lipid profiles throughout pregnancy

Lepsch, Jaqueline; Eshriqui, Ilana; Farias, Dayana Rodrigues; Vaz, Juliana dos Santos; Figueiredo, Amanda Faria de; Adegboye, Amanda Rodrigues Amorim; Brito, Alex; Mokhtar, Rana; Allen, Lindsay H.; Holick, Michael F.; Kac, Gilberto

doi:10.1016/j.metabol.2017.02.004

Cited by 27 publications

(24 citation statements)

References 40 publications

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“…We found inverse cross‐sectional associations between 25(OH)D concentrations and total cholesterol and triglyceride levels at 12–15 wk gestation, which persisted after adjusting for maternal factors. This is consistent with a previous study where 25(OH)D <75 nmol/L in the first trimester was associated with higher total and LDL cholesterol . In contrast, Al‐Ajlan et al.…”

Section: Discussionsupporting

confidence: 93%

“…We found inverse cross-sectional associations between 25(OH)D concentrations and total cholesterol and triglyceride levels at 12-15 wk gestation, which persisted after adjusting for maternal factors. This is consistent with a previous study where 25(OH)D <75 nmol/L in the first trimester was associated with higher total and LDL cholesterol [35]. In contrast, Al-Ajlan et al [36] reported that first trimester 25(OH)D concentrations were positively associated with serum lipids, which was thought to be due to increased lipid synthesis in response to high metabolic demands in early pregnancy [36].…”

Section: Discussionsupporting

confidence: 91%

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Relationship between vitamin D and gestational diabetes in overweight or obese pregnant women may be mediated by adiponectin

Mousa

Abell

Shorakae

et al. 2017

Molecular Nutrition Food Res

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 91%

Relationship between vitamin D and gestational diabetes in overweight or obese pregnant women may be mediated by adiponectin

Mousa

Abell

Shorakae

et al. 2017

Molecular Nutrition Food Res

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“…Several studies have reported the relationship between circulating 25(OH)D concentrations and lipid profile in different age and sex subgroups (31)(32)(33)(34). However, in some other studies no association has been observed (35).…”

Section: Discussionmentioning

confidence: 99%

Hypovitaminosis D in Adults Living in a Sunny City: Relation to Some Cardiometabolic Risk Factors, National Food and Nutrition Surveillance

Nikooyeh

Hajifaraji

Yarparvar³

et al. 2018

Nutr Food Sci Res

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A B S T R A C T Background and Objectives:Reports indicate that hypovitaminosis D is extremely common worldwide and is reemerging as a major health problem globally. In the present study, the main objectives were: 1) to examine whether healthy men and women living in Ahvaz have adequate vitamin D status; 2) to assess association between vitamin D status and some cardiometabolic risk factors. Materials and Methods: Conclusions:We found high prevalence of hypovitaminosis D in apparently healthy adults in Ahvaz, a sunny city of Iran. Our findings suggest that high vitamin D concentrations among the adult population are associated with a substantial decrease in body mass index. However, there was no association with the lipid profile components.

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“…Some studies indicated this relationship [100], while other studies failed to support it [76,101]. The findings show a positive correlation between serum vitamin D and atherogenic factors such as total cholesterol and triglycerides [102,103]. As vitamin D has immunomodulatory effects, it may have a protective role against mother-to-child transmission (MTCT) of the human immunodeficiency virus (HIV).…”

Section: Other Related Outcomesmentioning

confidence: 99%

Maternal Vitamin D Status among Different Ethnic Groups and Its Potential Contribution to Adverse Pregnancy and Child Outcomes

Keshavarz¹,

Jandaghi²,

Shafiee³

et al. 2020

Vitamin D Deficiency

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Maternal vitamin D deficiency in pregnancy is a widespread public health concern. Race and ethnicity as biological and cultural factors, respectively, can affect vitamin D status through differences in skin color, sunlight exposure, and dietary intake. Low maternal vitamin D status in pregnancy may affect both mother and fetus adversely. Vitamin D deficiency and insufficiency are linked to a wide variety of adverse pregnancy outcomes such as gestational diabetes, preeclampsia, and preterm delivery. Furthermore, maternal vitamin D deficiency has been linked to several adverse health outcomes in infants and children. The examples include, but not limited to, impaired growth, skeletal problems, and autoimmune diseases such as type 1 diabetes and asthma. This chapter reviews the vitamin D status during pregnancy across different ethnic groups, looking into the adverse pregnancy and child outcomes, followed by a discussion on the association between maternal and child vitamin D status and successful interventions. Strong evidence exists about the association between vitamin D and some health outcomes during pregnancy, while more studies are needed to confirm the other claim. The existing body of evidence justifies the need for well-designed policies and systematic interventions to ensure optimal vitamin D status of pregnant women and their offsprings across different ethnic and racial groups.

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Association between early pregnancy vitamin D status and changes in serum lipid profiles throughout pregnancy

Cited by 27 publications

References 40 publications

Relationship between vitamin D and gestational diabetes in overweight or obese pregnant women may be mediated by adiponectin

Relationship between vitamin D and gestational diabetes in overweight or obese pregnant women may be mediated by adiponectin

Hypovitaminosis D in Adults Living in a Sunny City: Relation to Some Cardiometabolic Risk Factors, National Food and Nutrition Surveillance

Maternal Vitamin D Status among Different Ethnic Groups and Its Potential Contribution to Adverse Pregnancy and Child Outcomes

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