Association between late effects assessed by physicians and quality of life reported by head-and-neck cancer survivors

Abstract

Physician-assessed moderate to severe hoarseness and mild, moderate, or severe dysphagia are associated with clinically relevant decreases in patient-reported quality of life and functioning. Fibrosis and xerostomia of any severity were not associated with changes in any scale of functioning in this study population.

A longitudinal study of the Swedish MD Anderson Dysphagia Inventory in patients with oral cancer

“…There were statistically significant differences between the patients with T A B L E 4 MDADI scores before treatment (baseline) and follow-up (6 and 12 months) and a control group without dysphagia. Comparisons of changes within and between groups 4 This further strengthens the use of this threshold value in clinical praxis.…”

“…3 Swallowing problems are often associated with reduced health related quality of life (HRQL), morbidity, anxiety and depression. 3,4 Dysphagia is often monitored through functional assessment of swallowing ability, by for example videofluoroscopy or fiberoptic endoscopic evaluation of swallowing. In addition to this, instruments to measure the degree and impact of dysphagia are useful when evaluating the treatment and rehabilitation outcome and needs.…”

Dysphagia and Its Impact on Quality of Life of Head and Neck Cancer Patients: Institution Based Cross sectional Study

“…Similar to previous studies that reported patient-related factors such as, gender [16,19,20] and nancial burden [18,44,45], tumor-related factors such as advanced tumor stage [21][22][23], location of HNC [25][26][27][28][29] and type of treatment [15,25,30] ,this study also identi ed that female sex, low income (who can't cover their medical expenses), suffering from laryngeal/ hypo pharyngeal cancer, suffering from advanced tumor are key determinants of poor QoL related to swallowing problems in HNC patients. These results have direct implications at improving the care of HNC patients by highlighting the need to incorporate swallowing function in the assessment and clinical management of patients.…”

“…Factors predictive of poor quality of life (QoL) due to dysphagia could be patient-related [15] such as smoking [16][17][18], alcohol abuse [16], age [16,18,19], lean mass [16], and gender [16,19,20]; tumorrelated [15] such as advanced tumor stage [17,[21][22][23][24], location of HNC [25], such as patients with tongue [26], buccal [27], hypo pharyngeal [28] and laryngeal [29] tumors had worse dysphagia related QoL, type of treatment [15,25,30] in which higher level of dysphagia and lower QoL scores among patients who had radiotherapy [19], [31], [32], [29,33] and surgery [19,34,35] and patients treated with concomitant chemotherapy have an exacerbated dysphagia and dietary problems [36]. Deterioration in swallowing function through time were also reported from before treatment to 3 months [3,37,38] and 6 months [17,39] post treatment with some improvements at later times [17,37,38,…”

Validierung der deutschen Version des Eating Assessment Tool bei Kopf-Hals-Tumor-Patienten

“…Je nach Lokalisation und Größe eines Tumors sowie der Art der notwendigen onkologischen Therapie werden Prävalenzen von 5 bis 78 % dieser Folgeerkrankung in der Literatur angegeben [1][2][3][4]. Schluckbeschwerden sind mit tiefgreifenden sozialen, emotionalen und sozioökonomischen Auswirkungen assoziiert [5][6][7][8][9]. Moderne Diagnostik und modernes Management einer solchen Schluckstörung erfordern daher einen multidimensionalen Ansatz.…”