Association between lifestyle and anthropometric parameters and thyroid nodule features

Panagiotou, Grigorios; Komninou, Despina; Anagnostis, Panagiotis; Linardos, George; Karoglou, Eleni; Somali, Maria; Duntas, Leonidas H.; Kita, Marina; Τζιόμαλος, Κωνσταντίνος; Pazaitou‐Panayiotou, Kalliopi

doi:10.1007/s12020-017-1285-6

Cited by 38 publications

(39 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the connection between obesity and thyroid nodules is conflicting in the literature (Cappeli et al, 2012;Sousa et al, 2013), our study showed that the variables related to subcutaneous adiposity, cervical variables, were associated with a higher frequency of nodules. Moreover, a positive association between total body fat percentage and presence of thyroid nodules was verified in a cross-sectional study of 306 healthy individuals from northern Greece, which also agrees with our study findings (Panagiotou et al, 2017).…”

Section: Discussionsupporting

confidence: 92%

Factors Associated with the Occurrence of Thyroid Nodules in Severely Obese Patients: A Case-Control Study

Siqueira

Rodrigues

Silveira

2019

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

Background:The association of obesity with the occurrence of thyroid nodules and thyroid cancer has been demonstrated. However, there is limited knowledge on the risk factors of thyroid nodules in in severely obese patients. The aim was to evaluate the occurrence of thyroid nodules in severely obese and nonobese patients and determine the factors associated considering sociodemographic, lifestyle, and biochemical variables.Methods:This is a case-control study of 134 adults which 67 nonobese, control group, and 67 severely obese (BMI ≥ 35 kg/m2), case group. All participants underwent thyroid ultrasound.Results:The occurrence of thyroid nodules in a control group was 13.4% (n = 9), while in a case group was 29.9%, n = 20), difference statistically significant (p = 0.017). Factors associated with the occurrence of thyroid nodules in severely obese patients were lower mean age (p = 0.022); higher economic class (p = 0.010); nonconsumption of alcohol (p = 0.017); higher fasting glycemia (p = 0.009), fasting insulin (p = 0.001), homeostatic model assessment of insulin resistance [HOMA-IR] (p = 0.045), and triglyceride (p = 0.009) mean values; and lower vitamin D3 (p = 0.045) and high-density lipoprotein cholesterol (p = 0.041) mean values.Conclusions:Occurrence of thyroid nodules in severely obese patients was higher than nonobese. Lower age at diagnosis, higher economic level, nonconsumption of alcohol, hyperinsulinemia, higher HOMA-IR scores, and lower vitamin D3 levels were factors associated with the occurrence of thyroid nodules in severely obese patients.

show abstract

Section: Discussionsupporting

confidence: 92%

Factors Associated with the Occurrence of Thyroid Nodules in Severely Obese Patients: A Case-Control Study

Siqueira

Rodrigues

Silveira

2019

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

show abstract

“… 5 , 20 , 21 The differences in the prevalence may be due to age, gender, race, culture, dietary patterns, and iodine supplements. 7 , 22 , 23 …”

Section: Discussionmentioning

confidence: 99%

Thyroid nodules in centenarians: prevalence and relationship to lifestyle characteristics and dietary habits

Yao¹,

Chen²,

Wu³

et al. 2018

CIA

View full text Add to dashboard Cite

BackgroundThyroid nodules (TNs) are common thyroid lesions in older population. Few studies have focused on the prevalence of TNs and their relationship to lifestyle characteristics and dietary habits in centenarians. The current study aimed at determining the prevalence of TNs in Chinese centenarians by using high-resolution ultrasound (US) equipment and at investigating its relationship to lifestyle characteristics and dietary habits.Participants and methodsThe current study was part of the China Hainan Centenarian Cohort Study that was conducted in Hainan, an iodine-sufficient region in People’s Republic of China. A total of 874 permanent residents aged ≥100 years (mean age =102.8±2.8 years) without any missing data were included in the analysis.ResultsAmong the participants, 649 of them were detected at least one TN under the US examinations. The overall prevalence rate of TNs was 74.3%. The prevalence of TNs was higher in participants who were women, had hypertension, had diabetes, and were underweight compared with their counterparts. Multivariate logistic regression analyses showed that being female, hypertensive, and diabetic; betel quid consumption; and red meat consumption were independent risk factors, while being underweight and nut consumption were independent protective factors for TNs.ConclusionOur findings indicate that the presence of TNs was highly prevalent in Chinese centenarians, particularly in women. In addition to gender, having hypertension, having diabetes, and being underweight, the presence of TNs was independently associated with betel quid, red meat, and nut consumption. Further prospective studies are warranted to verify these associations in populations from different age strata, races, cultures, and iodine supplementation.

show abstract

“…Some well-known factors involved in the formation and progression of TN, such as age, gender, iodine deficiency, and thyroid-stimulating hormone (TSH) [3]. More recently, the role of systemic inflammatory response caused by unhealthy lifestyle such as high calorie intake, sedentary behaviour, and chronic stress in the pathophysiology of TN has also attracted the interest of researchers [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Monocyte-to-high-density lipoprotein cholesterol ratio is associated with the presence and size of thyroid nodule irrespective of the gender

Liu¹,

Wang²,

Ji³

et al. 2020

Lipids Health Dis

View full text Add to dashboard Cite

Background: Systemic inflammation may be involved in the formation and progression of thyroid nodule (TN). The aim of this large-scale study was to investigate the association of several simple inflammatory markers with the presence and size of TN. Methods: A total of 133,698 adults were included for the current analysis. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and monocyte-to-high-density lipoprotein cholesterol ratio (MHR) were calculated. The logistic regression was used to explore the association of the four markers with the presence and size of TN. Results: The prevalence of TN was 55.1% among females and 44% among males; 13% of women and 8% of men had non-micronodule. In women, MHR and PLR were significantly associated with the presence of TN and nonmicronodule; in men, MHR and NLR were significantly associated with the presence of TN and non-micronodule. Conclusions: As a low-cost, simple, and reproducible inflammatory marker, MHR is strongly associated with the presence and size of TN irrespective of the gender.

show abstract

Association between lifestyle and anthropometric parameters and thyroid nodule features

Cited by 38 publications

References 37 publications

Factors Associated with the Occurrence of Thyroid Nodules in Severely Obese Patients: A Case-Control Study

Factors Associated with the Occurrence of Thyroid Nodules in Severely Obese Patients: A Case-Control Study

Thyroid nodules in centenarians: prevalence and relationship to lifestyle characteristics and dietary habits

Monocyte-to-high-density lipoprotein cholesterol ratio is associated with the presence and size of thyroid nodule irrespective of the gender

Contact Info

Product

Resources

About