Association between medication adherence and quality of life of patients with diabetes and hypertension attending primary care clinics: a cross-sectional survey

Khayyat, Sarah M.; Mohamed, Mahmoud; Khayyat, Salwa M. Saeed; Alhazmi, Raghda S. Hyat; Korani, Mulham Fouad; Allugmani, Ebtesam Bakheet; Saleh, Sarah Fathallah; Mansouri, Deyaa Abdulla; Lamfon, Qasim A.; Beshiri, Osama Mohammed; Hadi, Muhammad Abdul

doi:10.1007/s11136-018-2060-8

Cited by 70 publications

(71 citation statements)

References 39 publications

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“…We used a single proportion formula in the WHO sample size calculator to determine the sample size for this study. We used an expected prevalence of non-adherence of 53% from a previous study [13]. At 95% confidence level and 6% bound on error, the required sample size was 266 hypertensive patients.…”

Section: Study Population and Sample Sizementioning

confidence: 99%

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Medication Adherence and Its Association With Quality of Life Among Hypertensive Patients Attending Primary Health Care Centers in Saudi Arabia

Alsaqabi¹,

Rabbani²

2020

Cureus

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Background Chronic diseases require long-term medication and adherence to medication is important for the control of disease as well as prevention of complications. Non-compliance may lead to worsening of the disease, which may affect patients' quality of life. This study aimed to assess the level of medication adherence and its association with quality of life (QOL) among hypertensive patients in Buraidah, Saudi Arabia. Methods A cross-sectional study was carried out in which 299 hypertensive patients were recruited from the randomly selected primary health care centers. Medication adherence was assessed by Hill-Bone Medication Adherence Scale, and quality of life was assessed by the World Health Organization's Quality of Life (WHOQOL)-BREF. Multivariate linear regression was used to assess the association of medication adherence with quality of life. Data was analyzed using SPSS version 21.0 (IBM Inc., Armonk, USA).

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Section: Study Population and Sample Sizementioning

confidence: 99%

“…In Saudi Arabia, only two studies have assessed medication adherence among hypertensive patients [11,12]. Only one study assessed the association between medication adherence and QOL of patients with chronic diseases within primary care settings [13].…”

Section: Introductionmentioning

confidence: 99%

Medication Adherence and Its Association With Quality of Life Among Hypertensive Patients Attending Primary Health Care Centers in Saudi Arabia

Alsaqabi¹,

Rabbani²

2020

Cureus

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“…Uchmanowicz and colleagues concluded that with an increasing QoL, the level of adherence to therapeutic recommendations among elderly hypertensive patients increases 40 . Further findings support an association between medication adherence and QoL among patients with hypertension (and/or diabetes) 41 . Whether this association holds true for CHF patients remains unclear.…”

Section: Discussionmentioning

confidence: 99%

“…40 Further findings support an association between medication adherence and QoL among patients with hypertension (and/or diabetes). 41 Whether this association holds true for CHF patients remains unclear. Our data do not suggest a significantly different effect of the intervention on HF-related QoL between patients with high (PDC ≥ 80%) compared with low adherence to HF medications (PDC < 80%), both during 365 and 730 days post randomization.…”

Section: Figurementioning

confidence: 99%

The impact of pharmacist/physician care on quality of life in elderly heart failure patients: results of the PHARM‐CHF randomized controlled trial

et al. 2020

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Aims Patients with heart failure (HF) have impaired quality of life (QoL). The randomized controlled trial PHARM-CHF investigated whether an interdisciplinary intervention consisting of regular contacts with the community pharmacy and weekly dosing aids improves medication adherence in patients with HF. It is unknown how an intervention involving frequent structured pharmacy visits affects QoL. Our aim was to explore adherence to the intervention and effects on QoL. Methods and results Among 237 patients, n = 110 were randomized to pharmacy care and n = 127 to usual care. The pharmacy care group received a medication review followed by (bi-)weekly dose dispensing and counselling. The median follow-up was 2.0 years [inter-quartile range (IQR) 1.2-2.7]. Median interval between pharmacy visits was 8.4 days (IQR 8.0-10.3) and the visits lasted in median 14 min (IQR 10-15). Median adherence to the intervention was 96% (IQR 84-100). QoL at 365 days was predefined as a main secondary and at 730 days as another secondary endpoint in PHARM-CHF. QoL was measured by the Minnesota Living with Heart Failure Questionnaire; and for 111 patients (n = 47 in the pharmacy care group and n = 64 in the usual care group), data were available at baseline, and after 365 and 730 days (mean age 74 years; 41% female). Improvement in QoL was numerically higher in the pharmacy care group after 365 days and was significantly better after 730 days (difference in total scores À7.7 points [À14.5 to À1.0]; P = 0.026) compared to the usual care group. In all subgroups examined, this treatment effect was preserved. Improvements in the physical and emotional dimensions were numerically higher in the pharmacy care group after 365 days and were significantly better after 730 days: À4.0 points [À6.9 to À1.2]; P = 0.006, and À1.9 points [À3.7 to À0.1]; P = 0.039, respectively. Conclusions A pharmacy-based interdisciplinary intervention was well received by the patients and suggests clinically important improvements in QoL.

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“…14 Treatment is seeing to be non-effective nowadays because of their improper compliance or non-adherence to therapy which in turn lower the quality of life. 16 As CPs are more close to the patients in their daily routine practice, they can more get involve or engage in promoting medication adherence by providing proper counselling and awareness. 17 In our research, 119 (91.54%) HCPs agreed and shared that CPs can encourage the patients for better medication adherence.…”

Section: Perception Of Hcps On Pharmdmentioning

confidence: 99%

Role of Pharm.D in Better Patient Care: Perspective of Indian Health Care Practitioners

Venkataraman¹,

Rashid²,

Cherian³

et al. 2019

IJOPP

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Background: Clinical Pharmacists (CP) are less prized in direct patient care compared to both physicians and nurses even though most of the professionals identified that the CP is an inexorable part of the medical team. Objectives: To explore the perception of Health care Practitioners (HCPs) towards the Pharm.D and Services provided by the CPs from the Indian perspective. Methodology: A 10 items questionnaire-based cross-sectional survey was conducted through surveying HCPs including medical, nursing, pharmacy and the academician about their perceptions regarding the Pharm.D program and the clinical pharmacy services providing by the CPs in a tertiary care teaching hospital situated in the south Indian state Karnataka. Results: A total of 130 volunteers participated including 91 medical doctors or students, 6 pharmacists who work in the hospital, 17 nurses, 3 academicians and other 13 didn't mention their profession. In the study, 91.54% (119) accepted that CPs can play a vital role in improving the medication adherence through the patient counselling and 92.31% (120) HCPs were agreed that CPs can provide appropriate interventions for better patient care. Their efforts in drug interactions and ADRs are really appreciated and 82.31% (107) recommended CP as an integral part of the multidisciplinary health care team. Conclusion: Our research suggests that CPs can be an asset to the health care practice especially in India through partnering the HCPs in better patient care by providing the appropriate interventions. Still, there is an emergent need for more practical emphasised syllabus and curriculum to make the Pharm.D graduates more employable.

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Association between medication adherence and quality of life of patients with diabetes and hypertension attending primary care clinics: a cross-sectional survey

Cited by 70 publications

References 39 publications

Medication Adherence and Its Association With Quality of Life Among Hypertensive Patients Attending Primary Health Care Centers in Saudi Arabia

Medication Adherence and Its Association With Quality of Life Among Hypertensive Patients Attending Primary Health Care Centers in Saudi Arabia

The impact of pharmacist/physician care on quality of life in elderly heart failure patients: results of the PHARM‐CHF randomized controlled trial

Role of Pharm.D in Better Patient Care: Perspective of Indian Health Care Practitioners

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