Association between nonalcoholic fatty liver disease and coronary artery disease

Vilar, Consuelo P.; Cotrim, Helma Pinchemel; Florentino, Gesira Soares de Assis; Barreto, Cibelle P.V.; Florentino, André Vinicius A.; Bragagnoli, Gérson; Schwingel, Paulo Adriano

doi:10.1016/s2255-4823(13)70472-7

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“…For example, the presence of NAFLD is known to carry an increased risk of coronary heart disease (CHD), acute myocardial infarction and association with higher mortality due to CHD in general 31 . In conclusion, our observations confirm that a large proportion of patients with high-risk factors (DM2, metabolic syndrome) have NAFLD(ref.…”

Section: Discussionmentioning

confidence: 99%

The prevalence of nonalcoholic liver steatosis in patients with type 2 diabetes mellitus in the Czech Republic

Dvořák¹,

Hainer²,

Petrtýl³

et al. 2015

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Aims. Nonalcoholic fatty liver disease (NAFLD) is associated with components of the metabolic syndrome (MS) but the prevalence of NAFLD in the Czech Republic is unknown. The aim of this study was to assess the latter in patients with type 2 diabetes (DM2) and to compare the noninvasive fibrosis scores with ultrasound findings in those patients. Methods. 180 consecutive patients with DM2 (mean age 64.2±9.3 years, 63% men) were examined for liver biochemistry, MS parameters and had liver ultrasound. MS was diagnosed according to the International Diabetes Federation. The diagnosis of NAFLD was based on liver ultrasound. Other aetiology of liver lesion was ruled out. Additionally, AST/ALT ratio, APRI, NAFLD fibrosis score, FIB4 and BARD scores were calculated. Conclusion.Patients with DM2 had in the majority of cases NAFLD which was related to weight, BMI, waist circumference and serum triglycerides. The validity of the liver fibrosis scoring system has to be assessed in those patients in the future.

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Section: Discussionmentioning

confidence: 99%