Association between obesity and health-related quality of life in patients with coronary artery disease

Oreopoulos, Antigone; Padwal, Raj; McAlister, F.A.; Ezekowitz, Justin A.; Sharma, Arya M.; Kalantar-Zadeh, Kamyar; Fonarow, Gregg C.; Norris, Colleen M.

doi:10.1038/ijo.2010.73

Cited by 48 publications

(34 citation statements)

References 38 publications

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“…However, some studies emphasized the association between obesity and HRQL [10–13], and failed to include a comparative analysis of the underweight group relative to other body weight groups [44,45]. There was substantial percentage of underweight persons [22,46] in Asian countries, including China.…”

Section: Discussionmentioning

confidence: 99%

“…McDonough et al [12] provided further evidence for the association between increasing BMI and poorer HRQL in a mixed population of white European (WE) and South Asian (SA) ethnicity, whilst suggested that SA ethnicity modify this relationship. Oreopoulos [13] reported that BMI was inversely associated with the physical function and overall HRQL in coronary artery disease (CAD) patients, especially those with severe obesity.…”

Section: Introductionmentioning

confidence: 99%

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Association between Body Mass Index and Health-Related Quality of Life: The "Obesity Paradox" in 21,218 Adults of the Chinese General Population

et al. 2015

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BackgroundThere was no consistent recognition of the association between high or low body mass index (BMI) and health related quality of life (HRQL). The aim of this research was to study the association between BMI and HRQL in Chinese adults, and to further explore the stability of that association in the subgroup analysis stratified by status of chronic conditions.MethodsA total of 21,218 adults aged 18 and older were classified as underweight, normal weight, overweight, class I obese, and class II obese based on their BMI. HRQL was measured by the SF-36 Health Survey. The independent impact of each BMI category on HRQL was examined through standard least squares regression by comparing the difference of SF-36 scores and the minimum clinically important differences (MCID), which was defined as 3 points.ResultsCompared to the normal weight, the class I obese was significantly associated with better HRQL scores in the mental component summary (MCS) (75.1 vs. 73.4, P<0.001). The underweight had the lowest score in both the physical components summary (PCS) (75.4 vs. 77.5, P<0.001) and mental components summary (MCS) (71.8 vs. 73.4, P<0.001). For the MCID, the HRQL score was reduced by more than 3 points in the physical functioning for the class II obese (D=-3.43) and the general health for the underweight (D=-3.71). Stratified analyses showed a similar result in the health subjects and chronic conditions, and it was significant in the chronic conditions.ConclusionsThe class I obese showed the best HRQL, especially in the mental domain. The worst HRQL was found in the underweight. The class II obese reduced HRQL in the physical functioning only. “Obesity paradox” was more obvious in the participants with chronic conditions.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Association between Body Mass Index and Health-Related Quality of Life: The "Obesity Paradox" in 21,218 Adults of the Chinese General Population

et al. 2015

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“…Weight loss in overweight and obese persons through diet and/or exercise can confer a host of metabolic benefits (1, 2). Although energy restriction alone often leads to weight loss, the tissue composition of the loss includes lean tissue (3–5), which could have deleterious metabolic consequences.…”

Section: Introductionmentioning

confidence: 99%

Increased Consumption of Dairy Foods and Protein during Diet- and Exercise-Induced Weight Loss Promotes Fat Mass Loss and Lean Mass Gain in Overweight and Obese Premenopausal Women

Josse

Atkinson

Tarnopolsky

et al. 2011

The Journal of Nutrition

205

197

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Weight loss can have substantial health benefits for overweight or obese persons; however, the ratio of fat:lean tissue loss may be more important. We aimed to determine how daily exercise (resistance and/or aerobic) and a hypoenergetic diet varying in protein and calcium content from dairy foods would affect the composition of weight lost in otherwise healthy, premenopausal, overweight, and obese women. Ninety participants were randomized to 3 groups (n = 30/group): high protein, high dairy (HPHD), adequate protein, medium dairy (APMD), and adequate protein, low dairy (APLD) differing in the quantity of total dietary protein and dairy food-source protein consumed: 30 and 15%, 15 and 7.5%, or 15 and <2% of energy, respectively. Body composition was measured by DXA at 0, 8, and 16 wk and MRI (n = 39) to assess visceral adipose tissue (VAT) volume at 0 and 16 wk. All groups lost body weight (P < 0.05) and fat (P < 0.01); however, fat loss during wk 8–16 was greater in the HPHD group than in the APMD and APLD groups (P < 0.05). The HPHD group gained lean tissue with a greater increase during 8–16 wk than the APMD group, which maintained lean mass and the APLD group, which lost lean mass (P < 0.05). The HPHD group also lost more VAT as assessed by MRI (P < 0.05) and trunk fat as assessed by DXA (P < 0.005) than the APLD group. The reduction in VAT in all groups was correlated with intakes of calcium (r = 0.40; P < 0.05) and protein (r = 0.32; P < 0.05). Therefore, diet- and exercise-induced weight loss with higher protein and increased dairy product intakes promotes more favorable body composition changes in women characterized by greater total and visceral fat loss and lean mass gain.

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“…However, evidence regarding the direct association between lifestyle changes and HRQoL in coronary patients is scarce. Some studies report on the association between HRQoL and smoking cessation, weight loss or physical activity, however to our knowledge, no study had investigated the association of lifestyle changes in coronary patients with various HRQoL measures in a systematic manner (12)(13)(14)(15)(16)(17).…”

Section: Introductionmentioning

confidence: 99%

The association between self‐reported lifestyle changes and health-related quality of life in coronary patients: the EUROASPIRE III survey

Smedt

Clays

Annemans

et al. 2013

Eur J Prev Cardiolog

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Background: Patients with coronary heart disease often suffer from an impaired health-related quality of life (HRQoL). A healthier lifestyle not only extends individuals' lengths of life but might also improve their HRQoL. The aim of this study was to explore the relation between self-reported lifestyle changes and HRQoL in European coronary patients. Methods: Data on 8745 coronary patients, from 22 countries, participating in the EUROASPIRE III survey (2006)(2007) were used. These patients hospitalized for coronary artery bypass graft, percutaneous coronary intervention, acute myocardial infarction, or myocardial ischaemia were interviewed and examined at least 6 months and no later than 3 years after their hospital admission to gather information on their HRQoL, self-reported lifestyle changes, and risk factors. Results: Significantly better HRQoL scores were found in ex-smokers compared to current smokers. Patients who made an attempt to increase their physical activity level had a better HRQoL compared to those who had not made an attempt. Furthermore dietary changes were associated with HRQoL, with better outcomes in patients who tried to reduce fat and salt intake and increase fish, fruit, and vegetable intake. The intention to change behaviour was not associated with HRQoL. Conclusions: Better HRQoL scores were found in those coronary patients who adopted a healthier lifestyle. The actual lifestyle changes -smoking cessation, increasing physical activity, and adopting a healthy diet -and not the intention to change are associated with better HRQoL outcomes.

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Association between obesity and health-related quality of life in patients with coronary artery disease

Cited by 48 publications

References 38 publications

Association between Body Mass Index and Health-Related Quality of Life: The "Obesity Paradox" in 21,218 Adults of the Chinese General Population

Association between Body Mass Index and Health-Related Quality of Life: The "Obesity Paradox" in 21,218 Adults of the Chinese General Population

Increased Consumption of Dairy Foods and Protein during Diet- and Exercise-Induced Weight Loss Promotes Fat Mass Loss and Lean Mass Gain in Overweight and Obese Premenopausal Women

The association between self‐reported lifestyle changes and health-related quality of life in coronary patients: the EUROASPIRE III survey

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