Association between parent attitudes and receipt of human papillomavirus vaccine in adolescents

Abstract

BackgroundHuman papillomavirus (HPV) vaccine coverage rates remain low. This is believed to reflect parental hesitancy, but few studies have examined how changes in parents’ attitudes impact HPV vaccine uptake. This study examined the association between changes in parents’ vaccine attitudes and HPV vaccine receipt in their adolescent children.MethodsA baseline and 1-year follow-up survey of HPV vaccine attitudes was administered to parents of 11–17 year olds who had not completed the HPV vaccine series. Changes in attitudinal scores (barriers, harms, ineffectiveness, and uncertainties) from the Carolina HPV Immunization Attitudes and Beliefs Scale were assessed. Two outcomes were measured (in parents’ adolescent children) over an 18-month period and analyzed using multivariable regression; receipt of next scheduled HPV vaccine dose and 3-dose series completion.ResultsThere were 221 parents who completed the baseline survey (11% response rate) and 164 with available follow-up data; 60% of their adolescent children received a next HPV vaccine dose and 38% completed the vaccine series at follow-up. Decrease in parents’ uncertainties was a significant predictor of vaccine receipt, with each 1-point reduction in uncertainties score associated with 4.9 higher odds of receipt of the next vaccine dose. Higher baseline harms score was the only significant predictor of lower series completion.ConclusionsReductions in parents’ uncertainties appeared to result in greater likelihood of their children receiving the HPV vaccine. Only baseline concerns about vaccine harms were associated with lower series completion rate. Education for parents should emphasize the HPV vaccine’s safety profile.

Factors associated with hindering the acceptance of HPV vaccination among caregivers - A cross-sectional study in Argentina

“…Contrary to our findings, other studies in high income countries have found that HPV knowledge and fear of adverse events could be important barriers to HPV vaccine uptake [32,[39][40][41]. Ogilvie et al found that in British Columbia, Canada, the main reason for having girls vaccinated was the vaccine's effectiveness, while the main reasons for not having girls receive the vaccine were concerns about its safety, preference to wait until girls were older, and not enough information to make informed decisions [32].…”

“…This is supported by other studies which have found similar results. For example, VanWormer PLOS ONE et al showed that neither physicians' nor nurses' recommendations to get the HPV vaccine in the previous year were associated with the actual receipt of the next HPV vaccine dose [40]. It is worth noting that in our study, only 72% of caregivers reported to have been advised by physicians to vaccinate their daughters.…”

“…Ogilvie et al found that in British Columbia, Canada, the main reason for having girls vaccinated was the vaccine's effectiveness, while the main reasons for not having girls receive the vaccine were concerns about its safety, preference to wait until girls were older, and not enough information to make informed decisions [32]. VanWormer et al assessed how changes in parents' attitudes were associated with improvements in HPV vaccine uptake in the United States [40]. Despite acceptability being relatively high, parental concerns about the HPV vaccine's safety appeared to be the most important barrier.…”

Using an integrated conceptual framework to investigate parents' HPV vaccine decision for their daughters and sons

“…38 The present study was unique in evaluating PAPM stages for both parents of girls and boys. The literature has primarily focused on parents of girls, 35,[37][38][39][40][41][42][43][44] with none using the PAPM.…”

Recruitment and reach in a pragmatic behavioral weight loss randomized controlled trial: implications for real-world primary care practice

“…For the 10 Marshfield Clinic sites, additional characteristics were available from EMR extraction for all patients who met the initial eligibility criteria of age, BMI, rural residence, clinic visit within 18 months, and were medically-homed to the Marshfield Clinic Health System with reasonably complete capture of all medical care, per standard quality reporting definitions used by the Marshfield Clinic Institute for Quality, Innovation and Patient Safety [26]. Additional extracted variables included comorbid conditions, smoking status, number of ambulatory visits, and in-patient days over the past 3 years.…”