Association Between Platelet Count and Components of Metabolic Syndrome in Geriatric Taiwanese Women

Chen, Yen‐Lin; Hsu, Chun-Hsien; Hseih, Chang-Hsung; Wang, Kun; Wu, Chung-Ze; Chen, Ming-Fong; Wang, Jen‐Yu; Chang, Jia-Kan; Pei, Dee

doi:10.1016/j.ijge.2012.01.015

Cited by 8 publications

(3 citation statements)

References 35 publications

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“…What is more interesting is that hemoglobin (Hb), platelet (PLT) count, and mean platelet volume (MPV) all had similar relationships. This evidence strongly implies an association between hematogram components and chronic inflammation [ 10 – 14 ]. Although a number of studies have been published with younger adults [ 4 – 12 ], little is known about the similar relationships between hematogram and MetS components among the elderly.…”

Section: Introductionmentioning

confidence: 99%

Association of complete blood cell counts with metabolic syndrome in an elderly population

Chen

Chang

et al. 2016

BMC Geriatr

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BackgroundMetabolic syndrome’s (MetS) role in predicting cardiovascular diseases and diabetes has been confirmed in many large cohort studies. Nontraditionally, hematogram components are significantly related to MetS in many different age groups. However, little is known about its role among the elderly.MethodsWe enrolled 18,907 subjects over the age of 65 years who underwent regular health examinations. They were divided into three groups according to age: young old (YO: ≥ 65 and < 74 years old), old old (OO: ≥ 75 and < 84 years old), and oldest old (ODO: ≥ 85 years old). The MetS components were determined, and correlations between MetS and hematogram components were evaluated using Pearson and multivariate linear regression analyses. The hematogram components were the independent variables evaluated separately against the dependent variable (MetS components).ResultsWhile SBP and HDL-C increased, most other MetS and hematogram parameters decreased in men with age. Fewer significant differences were noted among the women. In the YO and OO groups for both genders, the subjects with MetS had higher WBC and Hb. None of the hematogram components were different for subjects with or without MetS in the ODO group. Multiple regression results show that most of the relationships between hematogram and MetS components disappeared in the ODO groups. The WBC levels were mainly correlated with WC and TG. At the same time, Hb was associated with BP, FPG, and LDL-C. Compared to WBC and Hb, PLT was least related to MetS, except in the cases of LDL-C and TG. Among the MetS components, BMI, LDL-C, and TG were consistently related to all the hematogram components in YO and OO men. However, only TG had the same consistency among YO and OO women.ConclusionsThis study’s three major findings are as follows: WBC and Hb are associated with MetS, even among the YO and OO groups, regardless of gender; among the three hematogram components, Hb had the strongest and PLT had the weakest correlation with MetS; and TG is not the only component with relatively higher r values, and it is related to all hematogram components.

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Section: Introductionmentioning

confidence: 99%

Association of complete blood cell counts with metabolic syndrome in an elderly population

Chen

Chang

et al. 2016

BMC Geriatr

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“…What is more interesting is that hemoglobin (Hb), platelet (PLT) count, and mean platelet volume (MPV) all had similar relationships. This evidence strongly implies an association between hematogram components and chronic inflammation [10][11][12][13][14]. Although a number of studies have been published with younger adults [4][5][6][7][8][9][10][11][12], little is known about the similar relationships between hematogram and MetS components among the elderly.…”

Section: Introductionmentioning

confidence: 99%

Association of complete blood cell counts with metabolic syndrome in an elderly population

Li¹,

Chen²,

Chang³

et al. 2016

Diabetes Research and Clinical Practice

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“…White blood cell (WBC) count was one of the first inflammatory markers identified to be associated with MetS [4][5][6][7]. Subsequently, studies reported that not only WBC but also hemoglobin (Hb) and platelet (PLT) were associated with MetS by the possible mechanism of low-grade inflammatory status [8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Predicting metabolic syndrome by using hematogram models in elderly women

Liu¹,

Hsu²,

Lin³

et al. 2013

Platelets

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Association Between Platelet Count and Components of Metabolic Syndrome in Geriatric Taiwanese Women

Cited by 8 publications

References 35 publications

Association of complete blood cell counts with metabolic syndrome in an elderly population

Association of complete blood cell counts with metabolic syndrome in an elderly population

Association of complete blood cell counts with metabolic syndrome in an elderly population

Predicting metabolic syndrome by using hematogram models in elderly women

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