Association Between Poorer Quality of Life and Psychiatric Morbidity in Patients With Different Dermatological Conditions

Sampogna, Francesca; Picardi, Angelo; Chren, Mary Margaret; Melchi, C.F.; Pasquini, Paolo; Masini, Cinzia; Abeni, Damiano

doi:10.1097/01.psy.0000132869.96872.b2

Cited by 114 publications

(118 citation statements)

References 20 publications

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“…In the comparison of the Skindex-29 results with other dermatological diseases (Fig. S2 1 ) (28-34), the effect of EBS is comparable to psoriasis on the functioning and symptoms scale (33). On these scales, RDEB and JEB have the greatest recorded impairments in HRQoL after Hailey-Hailey disease (31).…”

Section: Discussionmentioning

confidence: 95%

Health-related Quality of Life in Epidermolysis Bullosa: Validation of the Dutch QOLEB Questionnaire and Assessment in the Dutch Population

Yuen¹,

Frew²,

Veerman³

et al. 2014

Acta Derm Venerol

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Wing Yan Yuen, Department of Dermatology, University Medical Center Groningen, Hanzeplein 1, NL-9700 RB Groningen, The Netherlands. E-mail: w.y.yuen@umcg.nl Epidermolysis bullosa (EB) consists of a spectrum of heritable trauma-induced blistering diseases of skin and mucous membranes (1). Many subtypes exist, and their clinical severity is variable, ranging from an occasional palmoplantar blister to childhood lethality (1). The health-related quality of life (HRQoL) is the impact of a disease on the physical, psychological, and social health of a patient (2). Defining HRQoL in EB patients is important in patient care and management (3). Furthermore, in recent years more focus has been placed on finding specific treatments for EB and measuring HRQoL can help in assessing the efficacy of these new treatment modalities (4, 5). Also, measuring and comparing HRQoL to other diseases can help assign funding to this rather unknown and rare disorder (4, 6). Measuring HRQoL is complicated by the wide range of phenotypes in EB, which all have their own clinical severity (3). Several studies have focused on qualitatively describing the impact of EB on patients' lives (7-11). Quantitative measurement of HRQoL has been performed using both generic and dermatology-specific instruments in EB patients (6, 12-15). However, due to ceiling effects and content validity issues of these instruments, the accuracy of the measurements is questionable. It has been hypothesised that, especially in the more severe EB subtypes, there has been an overestimation of the HRQoL (3). To overcome these problems, Frew et al. (3) developed and validated an EB-specific HRQoL measurement tool for older children and adults that can be used across all EB subtypes, called the QOLEB (quality of life in EB). Translation of the QOLEB, which was created and validated in English in Australia, to other cultures and languages may provide reliable comparisons of HRQoL in EB and the efficacy of clinical interventions across different countries (3). The aim of this study was to develop a validated and reliable QOLEB in Dutch, and to assess HRQoL in Dutch EB patients. MATERIALS AND METHODSThis study was performed at the Center for Blistering Diseases at the University Medical Center Groningen, which is the single national referral centre for EB in the Netherlands. Ethical approval was granted by the Medical Ethical Committee of the University Medical Center Groningen in the Netherlands. A signed consent form was obtained from all participating patients. Study measurement toolsThe English QOLEB is a validated and reliable adult EBspecific HRQoL tool consisting of a 17-item questionnaire, and it was developed by 2 of the authors (JWF and DFM) (3). The QOLEB measures 2 factors: functioning (questions 1-7, 9-10, 12-13, 15) and emotions (question 8, 11, 14, 16-17). For each question 4 optional answers exist that are scored from 0 to 3 points, in which a higher score represents a worse HRQoL. The functioning scale ranged from 0-36, the emotions scale from 0-15, and the ove...

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Section: Discussionmentioning

confidence: 95%

Health-related Quality of Life in Epidermolysis Bullosa: Validation of the Dutch QOLEB Questionnaire and Assessment in the Dutch Population

Yuen¹,

Frew²,

Veerman³

et al. 2014

Acta Derm Venerol

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“…Although many dermatologists think they have good insight into the impact of disease on their patients, the concordance between clinician-reported measurements of disease burden and PRO measures appears to be poor 21,22,23 . Little information about QoL is normally elicited during routine dermatology outpatient consultations 21 , though dermatologists clinical decisions in outpatients concerning psoriasis management are related to the degree of impact of psoriasis on the patient s QoL 24 .…”

Section: Discussionmentioning

confidence: 99%

Why quality of life measurement is important in dermatology clinical practice

Finlay

Salek

Abeni

et al. 2016

Acad Dermatol Venereol

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The aim of this study was to describe the many ways in which quality of life (QoL) measurement may potentially be advantageous in routine clinical dermatology practice. Thirteen members of the EADV Task Force on Quality of Life, eight dermatologists, three health psychologists, one epidemiologist and one pharmacoepidemiologist, independently listed all of the ways they thought this may be advantageous. 108 different way of using QoL information in clinical practice were suggested (median per participant=8, range=4-15), and were classified into 20 descriptive groups. These were sorted into five categories: Inform clinical decisions, Clinician-patient communication, Awareness of skin disease burden, Informing the consultation and Clinical service administration. The wide range of potential benefits identified may encourage clinicians to use these measures but also highlights many areas requiring evidence to establish the true value of routine use of QoL measures.

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“…Dermatolojik hastal›¤›n olmas› m› hastalar› depresyona sokmakta yoksa depresyon mu dermatolojik hastal›¤›n ortaya ç›k›fl›n› tetiklemektedir bilinmez. Baz› araflt›rmalarda dermatolojik hastal›klar›n kronik gidiflleri, beden imaj›na etkileri ve damgalanmaya yol açma olas›l›klar› yüzünden psikiyatrik hastal›klar›n ve özellikle depresyonun ortaya ç›k›fl›na yol açabildi-¤i vurgulan›r 17,25 . Buna karfl›n di¤er baz› araflt›rmalarda özellik-le psoriasis, atopik dermatit, kronik idiopatik ürtiker, alopesi areata ve akne gibi hastal›klar›n ortaya ç›k›fl› ve alevlenmesinde baflta depresyon olmak üzere tüm psikiyatrik hastal›klar›n önemli etkisi oldu¤u vurgulanmaktad›r 26 .…”

Section: Deri Ve Depresyonunclassified

“…Farkl› anksiyete bozukluklar›nda farkl› savunma mekanizmalar› devrededir. Örne¤in fobilerde yer de¤ifltirme mekanizmas› a¤›rl›k- [25][26][27][28][29][30][31][32][33][34][35] l› olarak kullan›l›r, obsesif kompulsif bozuklukta ise izolasyon, yapma bozma gibi mekanizmalar daha fazla kullan›lmaktad›r. Davran›flç› kurama göre anksiyete ö¤renilmifl koflullu bir yan›t-t›r.…”

Section: Anksiyete Bozuklu¤unun Etyolojisiunclassified

“…Çocuklu¤unda cinsel ve fiziksel tacize u¤rayan kiflilerde yetiflkinlikte kendine zarar verme davran›fl› s›k görülmektedir 97 . Bu hastalarda efllik eden alkol madde ba¤›ml›l›¤› olas›l›¤› da yüksektir ve e¤er kendine zarar verme [25][26][27][28][29][30][31][32][33][34][35] davran›fl› s›ras›nda kiflide disosiasyon oluyorsa kendileri de durumun fark›nda olmad›¤›ndan dermatolojik tan› koymak güç olabilmektedir. TSSB sonras› görülebilecek bu tür kendine zarar verme davran›fllar› aras›nda trikotillomani ve artefakt dermatiti say›labilir 97 .…”

Section: Travma Sonras› Stres Bozuklu¤uunclassified

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Deri Hastalıklarının Psikojenik Sonuçları ve Komorbiditeler

Mercan¹

2012

Turkderm

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Association Between Poorer Quality of Life and Psychiatric Morbidity in Patients With Different Dermatological Conditions

Cited by 114 publications

References 20 publications

Health-related Quality of Life in Epidermolysis Bullosa: Validation of the Dutch QOLEB Questionnaire and Assessment in the Dutch Population

Health-related Quality of Life in Epidermolysis Bullosa: Validation of the Dutch QOLEB Questionnaire and Assessment in the Dutch Population

Why quality of life measurement is important in dermatology clinical practice

Deri Hastalıklarının Psikojenik Sonuçları ve Komorbiditeler

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