Association between QRS duration on prehospital ECG and mortality in patients with suspected STEMI

Hansen, Rikke; Frydland, Martin; Helgestad, Ole Kristian Lerche; Lindholm, Matias Greve; Jensen, Lisette Okkels; Holmvang, Lene; Ravn, Hanne Berg; Kjærgaard, Jesper; Hassager, Christian; Møller, Jacob Eifer

doi:10.1016/j.ijcard.2017.07.049

Cited by 6 publications

(4 citation statements)

References 24 publications

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“…Less is known of the prognostic value of QRS duration on prehospital ECG in patients with STEMI in an contemporary population. These data are based on prospective assessment of all patients with confirmed STEMI where an prehospital ECG was available that were referred to two high volume primary PCI centers in Denmark [1] .…”

Section: Datamentioning

confidence: 99%

“… Data presented in this article relates to the research article entitled “ Association between QRS duration on prehospital ECG and mortality in patients with suspected STEMI” (Hansen et al, in press) [1] . Data on the prognostic effect of automatically recoded QRS duration on prehospital ECG and presence of classic left and right bundle branch block in 1777 consecutive patients with confirmed ST segment elevation AMI is presented.…”

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Data on association between QRS duration on prehospital ECG and mortality in patients with confirmed STEMI

et al. 2017

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Data presented in this article relates to the research article entitled “Association between QRS duration on prehospital ECG and mortality in patients with suspected STEMI” (Hansen et al., in press) [1].Data on the prognostic effect of automatically recoded QRS duration on prehospital ECG and presence of classic left and right bundle branch block in 1777 consecutive patients with confirmed ST segment elevation AMI is presented. Multivariable analysis, suggested that QRS duration >111 ms, left bundle branch block and right bundle branch block were independent predictors of 30 days all-cause mortality. For interpretation and discussion of these data, refer to the research article referenced above.

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Data on association between QRS duration on prehospital ECG and mortality in patients with confirmed STEMI

et al. 2017

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“…The QRS complex on a 12-lead electrocardiogram represents the electrical depolarization of the ventricular myocardium. Prolongation in QRS duration is associated with higher risk of adverse outcomes among individuals with cardiovascular disease (CVD) (1,2,3,4,5,6,7,8,9). In adults with heart failure with reduced ejection fraction (HFrEF), QRS duration and morphology are used to identify patients who may benefit from cardiac resynchronization therapy (CRT) (11).…”

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The Association of QRS Duration with Risk of Adverse Outcomes in Sex- and Race- Based Subgroups: The Dallas Heart Study

Kondamudi,

Zeleke,

Rosenblatt

et al. 2023

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Introduction: We explored sex and race differences in the prognostic implications of QRS prolongation among healthy adults. Methods: Participants from the Dallas Heart Study (DHS) free of cardiovascular (CV) disease who underwent ECG testing and cMRI evaluation were included. Multivariable linear regression was used to examine the cross-sectional association of QRS duration with left ventricular (LV) mass, LV ejection fraction (LVEF), and LV end diastolic volume (LVEDV). Association of QRS duration with risk of MACE was evaluated using Cox models. Interaction testing was performed between QRS duration and sex/race respectively for each outcome of interest. QRS duration was log transformed. Results: The study included 2,785 participants. Longer QRS duration was associated with higher LV mass, lower LVEF, and higher LVEDV, independent of CV risk factors ([?: 0.21, P<0.001], [?: -0.13, P<0.001], [?: 0.22, P<0.001] respectively). Men with longer QRS duration were more likely to have higher LV mass and higher LVEDV compared to women (P-int=0.012, P-int=0.01, respectively). Black participants with longer QRS duration were more likely to have higher LV mass as compared to White participants (P-int<0.001). In Cox analysis, QRS prolongation was associated with higher risk of MACE in women (HR = 6.66 [95% CI: 2.32, 19.1]) but not men. This association was attenuated after adjustment for CV risk factors, with a trend toward significance (HR = 2.45 [95% CI: 0.94, 6.39]). Longer QRS duration was not associated with risk of MACE in Black or White participants in the adjusted models. No interaction between sex/race and QRS duration for risk of MACE was observed. Discussion: In healthy adults, QRS duration is differentially associated with abnormalities in LV structure and function. These findings inform the use of QRS duration in identifying subgroups at risk for CV disease, and caution against using QRS duration cut offs uniformly for clinical decision making.

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Intravenous metoprolol during ongoing STEMI ameliorates markers of ischemic injury: a METOCARD-CNIC trial electrocardiographic study

et al. 2021

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Association between QRS duration on prehospital ECG and mortality in patients with suspected STEMI

Cited by 6 publications

References 24 publications

Data on association between QRS duration on prehospital ECG and mortality in patients with confirmed STEMI

Data on association between QRS duration on prehospital ECG and mortality in patients with confirmed STEMI

The Association of QRS Duration with Risk of Adverse Outcomes in Sex- and Race- Based Subgroups: The Dallas Heart Study

Intravenous metoprolol during ongoing STEMI ameliorates markers of ischemic injury: a METOCARD-CNIC trial electrocardiographic study

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