Association between sleep duration and metabolic syndrome: a cross-sectional study

Kim, Claire E.; Shin, Sangah; Lee, Hwi Won; Lim, Jiyeon; Lee, Jong Koo; Shin, Aesun; Kang, Daehee

doi:10.1186/s12889-018-5557-8

Cited by 89 publications

(83 citation statements)

References 42 publications

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“…In contrast, our findings on the association between short sleep duration and high glycated hemoglobin were not statistically significant in women or men, although a greater tendency for a positive association was observed among women. Regarding plasma lipids, similar to our results, Kim et al 41 did not identify associations between short sleep duration and dyslipidemia in women or men. However, meta-analyses highlight the lack of sufficient evidence to support any conclusion on this issue.…”

Section: Discussionsupporting

confidence: 91%

Sex differences in the association between self-reported sleep duration, insomnia symptoms and cardiometabolic risk factors: cross-sectional findings from ELSA-Brasil

Silva-Costa¹,

Rotenberg²,

Nobre³

et al. 2019

Preprint

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Background: The U-shaped associations between sleep durations and cardiometabolic risk factors (glycated hemoglobin levels, obesity, hypertriglyceridemia, hypertension and HDL-Cholesterol levels) are still inconclusive. Moreover, as sleep is comprised of quantitative and qualitative aspects, exploring both insomnia symptoms and sleep duration are relevant when evaluating the potential effects of sleep problems on health. The aim was to evaluate sex-specific associations between sleep problems and cardiometabolic risk factors. Methods: This cross-sectional study used data from wave two of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), including 7,491 women and 6,232 men. Questionnaires were administered to provide information about socioeconomic conditions, lifestyle, and sleep characteristics. A 12-hour fasting blood sample was drawn to measure serum cholesterol, triglycerides, and glycated hemoglobin. Blood pressure, weight and height were also measured using standard equipment. Generalized additive models were used to evaluate the curve shape of the relationship between self-reported sleep duration and the outcomes. Logistic regression was performed to investigate the magnitude of the associations of self-reported sleep duration, insomnia symptoms, and short sleep plus insomnia symptoms with cardiometabolic risk factors. Results: For women, self-reported sleep duration and insomnia symptoms (either separately or linked to short sleep duration) were associated with obesity, hypertension and glycated hemoglobin after adjusting for the confounders. The magnitudes of the associations between self-reported short sleep duration plus insomnia symptoms and the outcomes were slightly increased, considering sleep duration or insomnia symptoms separately. For men, both long sleep duration and insomnia symptoms were associated with hypertriglyceridemia after adjusted for the confounders. Conclusion: These findings suggest possible sex-specific patterns, since obesity, hypertension and high glycated hemoglobin were associated with self-reported sleep duration and insomnia symptoms in women, but not in men, and reinforce the importance of considering quantitative and qualitative aspects of sleep for the prevention and management of the outcomes.

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Section: Discussionsupporting

confidence: 91%

Sex differences in the association between self-reported sleep duration, insomnia symptoms and cardiometabolic risk factors: cross-sectional findings from ELSA-Brasil

Silva-Costa¹,

Rotenberg²,

Nobre³

et al. 2019

Preprint

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“…It has been reported several detrimental effects of long sleep for optimal health 61 . In addition, long sleep could increase fatigue, physiological deprivation, which could influence insulin resistance and hormonal imbalance 62 . Although the mechanisms are not clear, the above-mentioned mechanisms could have influenced this relationship.…”

Section: Discussionmentioning

confidence: 99%

Association between sleep quality and time with energy metabolism in sedentary adults

Jurado‐Fasoli

Mochón-Benguigui

Castillo

et al. 2020

Sci Rep

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the aim of the present study was to investigate the relationship of sleep quality and time with basal metabolic rate (BMR) and fuel oxidation in basal conditions and during exercise in sedentary middleaged adults. We also studied the mediation role of dietary intake and adherence to the traditional Mediterranean Diet in the relationship between sleep parameters and energy metabolism parameters.A secondary analysis of the FIT-AGEING study was undertaken. 70 middle-aged sedentary adults (40-65 years old) participated in the present study. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) and wrist accelerometers (ActiSleep, Actigraph, Pensacola, Florida, USA) for 7 consecutive days. BMR was measured with indirect calorimetry and fuel oxidation was estimated through stoichiometric equations. Maximal fat oxidation was determined by a walking graded exercise test and dietary intake with 24 h recalls. Adherence to the traditional Mediterranean diet was assessed through the PREDIMED questionnaire. PSQI global score (poor sleep quality) was associated with lower basal fat oxidation (BFox), both expressed in g/min and as a percentage of BMR, independently of confounders. We did not find any association between other sleep and energy metabolism parameters. No mediating role of the dietary intake or PREDIMED global score was observed in the association of PSQI and BFox. In conclusion, our study showed that a subjective poor sleep quality was associated with lower BFox, which is not mediated by dietary intake in sedentary adults. Cardiometabolic diseases and obesity are the leading causes of death in developed countries, becoming an epidemic in the last years 1,2. Unhealthy diets represent one of the top risk factors for cardiometabolic diseases and obesity, developing a positive energy balance 3. Simultaneously, a low basal metabolic rate (BMR), an impaired meal-induced thermogenesis and low physical activity levels could result in a reduced total energy expenditure 4. This low total energy expenditure coupled to high energy intake could produce a gradual weight gain and visceral adipose tissue deposition, increasing the risk of cardiometabolic diseases and obesity 5. The ability to oxidize fat as a fuel is considered an important metabolic health parameter 6. An impaired ability to oxidize fat is associated with an increased risk of obesity, type 2 diabetes mellitus, cardiovascular disease, metabolic syndrome, cancer and systemic inflammation 7. Therefore, fat oxidation in basal conditions (BFox) and maximal fat oxidation during exercise (MFO) are considered markers of metabolic health 8-10. Sleep pattern variations, including a decrease in the quality and quantity of sleep, have been shown to be also a risk factor for the development of obesity and cardiometabolic diseases 11. These changes in sleep quality and quantity disrupt the circadian rhythms and may have deleterious consequences on people health 12. Previous studies have provided a causal link between short sleep duration and poor sleep qu...

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“…Participants were asked about their weekday and weekend sleep duration via "During the past month, on an average school day, how many hours of actual sleep do you get at night?, " "Dring the past month, on an average weekend, how many hours of actual sleep do you get at night?" In line with other research, we converted the sleep duration into 4 groups (<6, 6-8, 8-10, and ≥10 h) (18). In the analysis, the most common duration was selected as reference, thus 6-8 h was selected as the reference category for weekday sleep duration, 8-10 h was selected as the reference category for weekend sleep duration.…”

Section: Sleep Problems Sleep Durationmentioning

confidence: 99%

Gender Differences in the Relationship Between Sleep Problems and Suicide Attempt in Adolescents

Wan

Wang

et al. 2020

Front. Psychiatry

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There are few studies examining which types of sleep problems are independently associated with suicide attempt (SA) and gender difference in adolescents. The aim of the present study was to examine whether specific sleep problems were uniquely associated with suicide attempt in adolescents and explore gender differences in the association. A school-based health survey was conducted in four provinces within China from November 2014 to January 2015. A total of 15,132 students aged 10-21 years completed standard questionnaires assessing past 12 month suicide attempt in addition to measures of sleep quality, quantity and sleep beliefs. 5.4% of participants reported a suicide attempt within the last 12 months. After adjustment for sociodemographic variables and psychological symptoms, almost all sleep problems remained significantly associated with a greater endorsement of suicide attempt. Further adjustment for co-occurring sleep problems revealed that weekday sleep duration (<6, 8-10, and ≥10 h), insomnia (often), and nightmares (sometimes and often) remained independently associated with suicide attempt in boys (p < 0.05). However in girls, weekday sleep duration (<6 and ≥10 h), weekend sleep duration (<6 h), midday nap (0 or 1-2 d/week), insomnia (sometimes and often), nightmare (often) and sleep beliefs (high) were independently associated with suicide attempt (p < 0.05). Multiple sleep problems are associated with suicide attempt in adolescents, however the relationship varies by gender.

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Association between sleep duration and metabolic syndrome: a cross-sectional study

Cited by 89 publications

References 42 publications

Sex differences in the association between self-reported sleep duration, insomnia symptoms and cardiometabolic risk factors: cross-sectional findings from ELSA-Brasil

Sex differences in the association between self-reported sleep duration, insomnia symptoms and cardiometabolic risk factors: cross-sectional findings from ELSA-Brasil

Association between sleep quality and time with energy metabolism in sedentary adults

Gender Differences in the Relationship Between Sleep Problems and Suicide Attempt in Adolescents

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