Association between social support, functional status, and change in health-related quality of life and changes in anxiety and depression in colorectal cancer patients

Tejada, M. Gonzalez-Saenz de; Bilbao, Amaia; Baré, Marisa; Briones, Eduardo; Sarasqueta, Cristina; Quintana, José M.; Escobar, Antonio

doi:10.1002/pon.4303

Cited by 126 publications

(119 citation statements)

References 40 publications

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“…This result corresponds to the finding reported by many existing studies that as illness-related distress increases, resilience (Fortier et al, 2013) and HRQOL (Molzon et al, 2017;Sharkey et al, 2017) decrease. Furthermore, among adolescents with significant social support, the levels of resilience (Haase et al, 1999(Haase et al, , 2014Hong & Park, 2015) and HRQOL (Arabyat & Raisch, 2015;Gonzalez-Saenz de Tejada et al, 2017) are high. Illness-related distress was the most influential factor on both resilience and HRQOL.…”

Section: Discussionmentioning

confidence: 99%

Impact of resilience on the health‐related quality of life of adolescents with a chronic health problem: A structural equation approach

Kim¹,

Kim

2018

Journal of Advanced Nursing

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Aim The aim of this study was to test the impact of resilience on the health‐related quality of life among adolescents with a chronic health problem, we established a structural model to explain patients’ health‐related quality of life. Background There are various resilience‐related factors with major effects on the health‐related quality of life among adolescents with a chronic disease; however, little is known about relationships among resilience, these influencing factors and direct and indirect effects of health‐related quality of life among adolescents with a chronic health problem. Design This study adopted a cross‐sectional, descriptive correlational design. Methods Participants were 220 adolescents with a chronic disease who were aged between 10 and 18 years and currently receiving treatment at a hospital or clinic for least 6 months from February to October 2017 in Korea. Results This study verifies that hope and courageous coping had direct effects on the resilience of adolescents with a chronic health problem and the level of direct effects on health‐related quality of life was in the following order: hope, resilience and courageous coping. In addition, illness‐related distress, social support, hope and defensive coping had indirect effects on resilience and the level of indirect effects on health‐related quality of life was in the following order: illness‐related distress, social support, defensive coping, hope and courageous coping. Conclusion Resilience is a major factor that improves health‐related quality of life among adolescents with a chronic health problem. In consideration of the direct and indirect paths verified through this study, it is necessary to develop interventions to improve health‐related quality of life among adolescents with a chronic health problem.

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Section: Discussionmentioning

confidence: 99%

Impact of resilience on the health‐related quality of life of adolescents with a chronic health problem: A structural equation approach

Kim¹,

Kim

2018

Journal of Advanced Nursing

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“…A number of studies have reported that chronic stress interferes with immune, endocrine and neural system functions. A number of epidemiological and clinical studies have reported that chronic stress plays an essential role in cancer occurrence, development and mortality, and reducing stress may prolong survival and decrease recurrence after therapy (14)(15)(16)(17). It has been demonstrated that chronic stress can activate the HPA axis and the SNS, leading to a release of catecholamines (NE, epinephrine and dopamine), glucocorticoids and other hormones.…”

Section: Discussionmentioning

confidence: 99%

Resveratrol inhibits the growth of tumor cells under chronic stress via the ADRB‑2‑HIF‑1α axis

Xue

Zhang

et al. 2018

Oncol Rep

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Resveratrol is a type of polyphenol that is abundantly present in knotweed and grapes, and has been confirmed to have tumor-inhibitory properties. However, the effect of resveratrol on tumor cells under chronic stress conditions remains unclear. The aim of the present study was to demonstrate that resveratrol exerts a significant inhibitory effect on the growth and proliferation of tumor cells under chronic stress in a dose-dependent manner. Furthermore, resveratrol was able to induce apoptosis of cancer cells under chronic stress conditions. Moreover, resveratrol was found to inhibit tumor cells under chronic stress by decreasing the expression of the β 2 -adrenergic receptor (ADRB-2); in addition, the protein expression of hypoxia-inducible factor (HIF)-1α was suppressed by resveratrol in a dose-dependent manner. Thus, these data suggest that resveratrol inhibits the growth of cancer cells under chronic stress by regulating the ADRB-2-HIF-1α axis. In summary, the present study may provide a new basis supporting the use of resveratrol for the prevention and treatment of pancreatic cancer.

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“…Anxiety and Depression were assessed with two items asking YBCS and relatives “Have you ever been told by a healthcare provider that you have anxiety?” yes/no and “Have you ever been told by a health care provider that you have depression?” yes/no. These variables were assessed because they interfere with support and communication, and better family functioning mitigates depressive symptoms among cancer patients …”

Section: Methodsmentioning

confidence: 99%

“…yes/no. These variables were assessed because they interfere with support and communication, 33,34 and better family functioning mitigates depressive symptoms among cancer patients. 35 Fear of Cancer Recurrence (YBCS only) was assessed with four items from the Concerns About Recurrence Scale (CARS) (eg, "How much time do you spend thinking about your breast cancer coming back") using a seven-point Likert scale from one "Not at all" to seven "All the time".…”

mentioning

confidence: 99%

Predictors and interdependence of family support in a random sample of long‐term young breast cancer survivors and their biological relatives

et al. 2018

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ObjectiveWomen diagnosed with breast cancer younger than 45 years (young breast cancer survivors—YBCS) and their biological relatives face significant stressors. Although family support is an important coping resource, little is known about YBCS’ and relatives’ support and whether it is interdependent. The study described family support in YBCS and their biological relatives; identified demographic, clinical, and psychosocial predictors of support; and determined the interdependence of support in YBCS‐relatives family units.MethodsData were collected from a random sample of YBCS and their first‐ or second‐degree female relatives. Actor‐partner interdependence models (APIM) explored predictors and interdependence of YBCS’ and relatives’ family support in dyads (YBCS and relative) and triads (YBCS and two relatives).ResultsAmong n = 310 YBCS and n = 431 first‐ or second‐degree relatives, family support was higher in triads compared to dyads. APIMs identified actor effects in dyads, and actor and partner effects in triads. Across all family units, YBCS’ higher self‐efficacy was associated with higher YBCS support (actor effect) and relative support (partner effect); YBCS’ prior diagnosis of depression was associated with lower YBCS and relative support (actor and partner effect); cost‐related lack of access to care was associated with lower support among YBCS (actor effect) and relatives (actor and partner effect).ConclusionsFamily support was interdependent and was affected by self‐efficacy, depression, and access to care. Interventions should include YBCS and relatives, enhance self‐efficacy and access to care.

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Association between social support, functional status, and change in health-related quality of life and changes in anxiety and depression in colorectal cancer patients

Abstract: Colorectal cancer patients who have more social support, are functionally independent and have higher improvements in HRQoL may have better results in anxiety and depression at 1 year after surgery, adjusting for age, gender, location, occupation, and baseline HADS scores.

Cited by 126 publications

References 40 publications

Impact of resilience on the health‐related quality of life of adolescents with a chronic health problem: A structural equation approach

Impact of resilience on the health‐related quality of life of adolescents with a chronic health problem: A structural equation approach

Resveratrol inhibits the growth of tumor cells under chronic stress via the ADRB‑2‑HIF‑1α axis

Predictors and interdependence of family support in a random sample of long‐term young breast cancer survivors and their biological relatives

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