Association Between VDR Polymorphisms and Breast Cancer: An Updated and Comparative Meta-analysis of Crude and Adjusted Odd Ratios

Role of vitamin D receptor gene Cdx2 and Apa1 polymorphisms in prostate cancer susceptibility: a meta-analysis

“…We excluded 266 studies unrelated to Vitamin D receptor (VDR) gene polymorphism, three studies unrelated to prostate cancer [34–36], and three reviews [37–39]. The remaining 20 studies were included in the meta-analysis.…”

Vitamin D Receptor Gene BSMI, FOKI, APAI, and TAQI Polymorphisms and the Risk of Atopic Dermatitis

“…Thus vitamin D metabolism may directly affect gene expression and regulation. Several studies have investigated the association between VDR polymorphisms and skin diseases (melanoma, basal cell carcinoma, vitiligo Behçet disease, psoriasis) [11][12][13][14][15]. The VDR gene is localized at chromosome 12q13.1 and numerous polymorphisms have been identified on the extensive promotor region of the gene (Figure 1).…”

Role of Vitamin D Deficiency and Lack of Sun Exposure in the Incidence of Premenopausal Breast Cancer: a Case Control Study in Sabzevar, Iran

“…Next findings focused on the protective role of sunlight exposure and its inverse association with breast density pattern in premenopausal women (Wu et al, 2013). Above study suggested that sunlight exposure may be associated with reduced risk of breast cancer without any clear evidence of modification by the vitamin D receptor (VDR) variant which is a crucial mediator for the cellular effects of vitamin D (Wu et al, 2013) and later studies didn't show any association between VDR BsmI polymorphism and increased risk of breast cancer (Du et al, 2013;Huang et al, 2014). In line with our findings, dressing style with body coverage has recently been shown to be important for vitamin D levels and breasat cancer in Turkey (Alco et al, 2014).…”