Purpose
Test whether equivalent changes in moderate (walking) and vigorous exercise (running) produce equivalent weight loss under free-living, non-experimental conditions.
Methods
Regression analyses of changes (Δ) in BMI vs. exercise energy expenditure (ΔMETh/d, 1 metabolic equivalent or MET=3.5 ml O2•kg−1•min−1) from survey questionnaires completed at baseline and 6.2 years thereafter in 15,237 walkers and 32,216 runners.
Results
At baseline, walkers spent less energy walking than runners spent running (mean±SD males: 2.22±1.65 vs. 5.31±3.12, females: 2.15±1.63 vs. 4.76±3.03 METh/d) and walkers were significantly heavier than runners (males: 26.63±4.04 vs. 24.09±2.58, females: 25.44±5.14 vs. 21.61±2.49 kg/m2). During follow-up, energy expenditure declined less for walking in walkers than for running in runners (males: −0.19±1.92 vs. −1.27±2.87, females: −0.30±1.93 vs. −1.28±2.85 METh/d). ΔBMI was inversely related to both ΔMETh/d run and ΔMETh/d walked, but more strongly to ΔMETh/d run than walked in men, and in heavier women. Specifically, the regression coefficient for ΔBMI vs. ΔMETh/d was significantly more negative for running than walking in men in the 1st quartile (differences in slope±SE: −0.06±0.03, P=0.01), 2nd quartile (−0.10±0.03, P=0.001), 3rd quartile (−0.17±0.03, P<10−8) and 4th quartile of BMI (−0.14±0.03, P<10−4) and in the 4th BMI quartile of women (−0.32±0.04 kg/m2 per METh/d, P<10−17). This represented 90% greater weight loss per METh/d run than walked in the 4th BMI quartile for both sexes. Age-related weight gain was attenuated by running in both sexes (P<10−6), and by walking in women (P=0.005).
Conclusion
Although ΔBMI was significantly associated with both ΔMETh/d run and walked, the ΔBMI was significantly greater for Δrunning than Δwalking.