Association of 3826A &gt;G UCP1 gene polymorphism and physical activity level with central obesity

Парфентьева, О.И.

doi:10.32521/2074-8132.2020.4.090-098

MUAB

2020

DOI: 10.32521/2074-8132.2020.4.090-098

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Association of 3826A >G UCP1 gene polymorphism and physical activity level with central obesity

О.И. Парфентьева¹

Abstract: Ñîãëàñíî äàííûì Âñåìèðíîé îðãàíèçàöèè çäðàâîîõðàíåíèÿ (ÂÎÇ) êîëè÷åñòâî ëþäåé, ó êîòîðûõ äèàãíîñòèðîâàëè èçáûòî÷íûé âåñ èëè îaeèðåíèå, çà ïîñëåäíèå 50 ëåò óâåëè÷èëîñü ïî÷òè â 3 ðàçà. Ïîëíîãåíîìíûé ïîèñê àññîöèàöèé âûÿâèë áîëåå 1000 îäíîíóêëåîòèäíûõ ïîëèìîðôèçìîâ, àññîöèèðîâàííûõ ñ ïîâûøåííûì ðèñêîì ðàçâèòèÿ îaeèðåíèÿ [

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2023

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Central obesity in the adult populations of the Altai Republic and the Republic of Tuva. Anthropological and genetic aspects

Парфентьева

Pravednikova

Айыжы

et al. 2023

VAAE

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In the present study, we identified the factors affected central obesity prevalence in the adult Altains, Russians and Tuvans permanently residing in the Altai and the Tuva Republics. The data was collected in 2018–2020. The examination program included anthropometrical examination and the genetic testing of females and males, aged 18–35 years. Anthropometrical examination was carried out in accordance with the guidelines accepted in the Research Institute and Museum of Anthropology. Body composition was analyzed by bioelectrical impedance analyzer. The SNPs rs1800592 UCP1, rs660339 UCP2 and rs1800849 UCP3 were assessed. The prevalence analyses of underweight, overweight and general obesity in the groups of female and males were conducted. The anthropometric indices were used to estimate the prevalence of central obesity. General obesity occurred more often in the group of Altai people, whereas in the Tuva people the central obesity is more pronounced. The Altai and Tuva people are alike in the total body measurements, whereas Russians were significantly higher. All studied groups demonstrated the sexual dimorphism of the body composition and waist to hip ratio. No significant differences in waist to height ratio between males and females were identified in the studied groups. No association between genetic variants and the obesity-related traits, which reflect the body fat and its distribution, was revealed. All factors included in the model are able to predict 8 % of the variability of the central obesity-related traits. Ethnic background contributes the most to the variability of the central obesity index.

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Central obesity in the adult populations of the Altai Republic and the Republic of Tuva. Anthropological and genetic aspects

Парфентьева

Pravednikova

Айыжы

et al. 2023

VAAE

View full text Add to dashboard Cite

show abstract

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Association of 3826A >G UCP1 gene polymorphism and physical activity level with central obesity

Cited by 1 publication

References 15 publications

Central obesity in the adult populations of the Altai Republic and the Republic of Tuva. Anthropological and genetic aspects

Central obesity in the adult populations of the Altai Republic and the Republic of Tuva. Anthropological and genetic aspects

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