Association of a Woman's Own Birth Weight With Subsequent Risk for Gestational Diabetes

Abstract

In this large population-based study, a woman's own birth weight was strongly and inversely related to her risk of GDM, suggesting that early life factors may be important in the etiology of this disorder.

Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature

“…Considering socioeconomic levels, Innes et al 21 did not find an association between gestational diabetes mellitus development and private or public insurance, occupation during pregnancy, or education of the parents of the pregnant woman at the time of her birth. However, they found an inverse association between the educational level of the pregnant woman and gestational diabetes mellitus, after adjustment for other social, economic and demographic factors.…”

“…Short stature associated to gestational diabetes mellitus had been found for all the groups in the crude analysis, although the association between Afro-Caribbean was not statistically significant 32 . On the other hand, studying several risks for the development of gestational diabetes mellitus, Di Cianni et al 33 and Innes et al 21 , respectively, in Italian and American populations, had also found a significant inverse association between height and gestational diabetes mellitus, even after adjustments for confounders.…”

“…Later in 2002, Innes et al 21 carried out a study enrolling 23,395 pregnant women that were born in New York State in the Unites States. The adjusted analyses had strengthened the inverse dose-response relationship and the magnitude of the association between low birth weight and the risk of gestational diabetes mellitus between women born weighing less than 2,000g (OR: 4.23; 95%CI: 1.55-11.51) in relation to those born with 3,500-3,999g.…”

“…As for the control of birth weight for gestational age, although it does not seem to change the association 20,21 , there is still no strong evidence to simply ignore such an adjustment.…”

Birthweight by Gestational Age and Sex at a Rural Referral Center

“…20 Birthweight may predict growth over the first years of life 21 and may be a risk factor for future medical conditions. 22,23 Our observation has been that a disproportionate percentage (>10%) of the newborns at our institution were designated as large for gestational age (LGA), which is usually assigned to newborns with birthweights above the 90th percentile for their gestational age. Since the LGA designation is associated with a greater risk of short-term morbidity, primarily hypoglycemia, 24 hyperbilirubinemia, polycythemia, 25 and obstetrical complications, 26 these newborns are often closely monitored, especially with repeated blood glucose determinations.…”