Association of cocaine- and amphetamine-regulated transcript and neuropeptide Y in the forebrain and pituitary of the catfish, Clarias batrachus: A double immunofluorescent labeling study

Singru, Praful S.; Mazumdar, Minakshi; Barsagade, Vikas G.; Lechan, Ronald M.; Thim, Lars; Clausen, Jes Thorn; Subhedar, Nishikant K.

doi:10.1016/j.jchemneu.2008.07.002

Cited by 18 publications

(22 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A lower expression of CART characterizes the porcine LPA and the MPN. Generally, porcine CART distribution is similar to the distribution described in previous studies in rats [20], humans [32] and lower vertebrates [30][31]. It is very difficult to precisely compare the distribution of CART in the porcine POA with the distribution in other species because there are only a few papers that deal with this issue and the division of the preoptic area differs in each species.…”

Section: Discussionsupporting

confidence: 57%

“…For example, in the frog, a large number of immunoreactive grains and fine varicose fiber terminals occupied the whole preoptic area and only a few CART-IR cells were observed [31]. In the catfish, most CART fibers were located in the lateral portion of the preoptic area with some CART-IR neurons in the preoptic periventricular nucleus [30].…”

Section: Discussionmentioning

confidence: 99%

“…Fibers that contain CART and fibers that contain NPY are present in the porcine preoptic area, in the porcine amygdala and in the infundibular nucleus of the rat, but these substances do not co--express within the same fibers [11,34]. However, these peptides were recently observed to co-localize in the infundibular nucleus in the human hypothalamus [39], and in the preoptic periventricular nucleus of the catfish [30]. CART and NPY innervation in the preoptic area of the pig, especially in the medial preoptic area, is very similar to the relationship described in the medial preoptic nucleus in humans [32] and in some hypothalamic nuclei in mice [35].…”

Section: Discussionmentioning

confidence: 99%

“…This area is reciprocally strictly connected with many hypothalamic nuclei [22][23][24], and it influences behavioral, neuroendocrine, and autonomic nervous system activity associated with reproduction, controlling male sexual behavior [25][26][27], regulating the cyclic release of pituitary gonadotropins [28] and helping regulate parental behavior [29]. There are only a few papers concerning CART peptide occurrence in the preoptic area [30][31][32] and the neuroanatomical distribution of CART and its chemical coding in the preoptic area has not been studied in detail.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Distribution and chemical coding pattern of the cocaine- and amphetamine-regulated transcript (CART) immunoreactivity in the preoptic area of the pig

Bogus‐Nowakowska¹,

Robak²,

Równiak³

et al. 2012

Folia Histochem Cytobiol.

View full text Add to dashboard Cite

Abstract:This study provides a detailed description of cocaine-and amphetamine-regulated transcript (CART) distribution and the co-localization pattern of CART and gonadotropin releasing hormone (GnRH), somatostatin (SOM), neuropeptide Y (NPY), cholecystokinin (CCK), and substance P (SP) in the preoptic area (POA) of the domestic pig. The POA displays a low density of immunoreactive cells and rich immunoreactivity for CART in fibers. CART-immunoreactive (CART-IR) cell bodies were single and faintly stained, and located in the medial preoptic area (MPA) and the periventricular region of the POA. A high density of immunoreactive fibers was observed in the periventricular preoptic nucleus (PPN); a high to moderate density of fibers was observed in the MPA; but in the dorso-medial region of the MPA the highest density of fibers in the whole POA was observed. The lateral preoptic area (LPA) exhibited a less dense concentration of CART-immunoreactive fibers than the MPA. The median preoptic nucleus (MPN) showed moderate to low expression of staining fibers. In the present study, dual-labeling immunohistochemistry was used to show that CART-IR cell bodies do not contain any GnRH and SP. CART-positive fibers were identified in close apposition with GnRH neurons. This suggests that CART may influence GnRH secretion. Double staining revealed that CART-IR structures do not co-express any of the substances we studied, but a very small population of CART-IR fibers also contain

show abstract

Section: Discussionsupporting

confidence: 57%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Distribution and chemical coding pattern of the cocaine- and amphetamine-regulated transcript (CART) immunoreactivity in the preoptic area of the pig

Bogus‐Nowakowska¹,

Robak²,

Równiak³

et al. 2012

Folia Histochem Cytobiol.

View full text Add to dashboard Cite

show abstract

“…In Crustacea, Kiris et al (2004) reported the effect of NPY on food intake and growth of penaeid shrimps. In fish, NPY has been detected in the rainbow trout Oncorhynchus mykiss (Larsson 2006) and catfish Clarias batrachus (Gaikwad et al 2004;Singru et al 2008). Ghrelin was also found in Drosophila (Hewes et al 2001), but no information is available on its function in this genus.…”

Section: Introductionmentioning

confidence: 99%

Review and perspectives of physiological mechanisms underlying genetically-based resistance of the Pacific oysterCrassostrea gigasto summer mortality

Samain

2011

Aquat. Living Resour.

View full text Add to dashboard Cite

-French oyster farming has been subject to severe mortalities during the summer months. Results from the research program "Morest", which ran from 2000 to 2006 and examined the possible causes of these mortalities, led to the construction of a model to explain the interaction between environmental factors, oyster physiology and different opportunistic pathogens underlying oyster summer mortality. Temperature, food, reproduction and stress were the main factors required for oyster mortality. Genetically-based resistance ("R" oysters) or susceptibility ("S" oysters) to summer mortality was revealed by divergent selection. Building on these results, a literature search was made in 2007 on the molecular origin of genetic resistance to such a complex mortality risk. The objectives were to lay a foundation for the preparation and orientation of future research directions and to improve understanding of the underlying physiological mechanism leading to summer mortality. Three years later, the resulting conceptual analysis reported here was presented as an introductory lecture to Physiomar 2010, a conference where many new results contributing to this research field were also reported. The literature review highlighted two major review articles: the first dealing with nutrition and reproduction (Schneider 2004), the second with reproduction, temperature, oxidative stress and mortality (Heineinger 2002). The effect of nutrition level on energy orientation to growth or reproduction is controlled by endocrine factors. Among these, neuropeptide Y (NPY), ghrelin and leptin neuropeptides appeared to be potential candidates involved in germ-soma orientation in relation to trophic conditions. Depending on reproductive effort and temperature, a metabolic stress resulting from the germ-soma conflict can appear, characterized by mitochondrial reactive oxygen species (ROS) production. Such an excess of ROS induces perturbations in mitochondrial activity leading to cell death. Many organisms, such as annual plants or the Pacific salmon, do not survive their first reproduction. In contrast, others increase stress resistance by selection of antioxidant processes (superoxide dismutase SOD, catalase, etc.) through evolution, and survive first reproduction. A similar difference was observed in the comparison made between R and S oysters, which differed in ROS production, SOD and catalase levels. Such factors controlling reproduction and ROS detoxification processes could therefore provide new markers for selection of oysters with better resistance to non-specific pathogens, complementing other classic selection approaches against specific pathogens or for improved immunity. This antioxidant defence mechanism is found in many organisms including vertebrates and in some invertebrates, including oysters. Its role needs to be considered in pathology events involving other aquaculture species and it may also contribute to explaining the increase in marine pathologies under anthropogenic environmental changes.

show abstract

Osteoporosis in the home health care setting: A window of opportunity?

Curtis

Kim

Bryant³

et al. 2006

Arthritis & Rheumatism

View full text Add to dashboard Cite

Association of cocaine- and amphetamine-regulated transcript and neuropeptide Y in the forebrain and pituitary of the catfish, Clarias batrachus: A double immunofluorescent labeling study

Cited by 18 publications

References 51 publications

Distribution and chemical coding pattern of the cocaine- and amphetamine-regulated transcript (CART) immunoreactivity in the preoptic area of the pig

Distribution and chemical coding pattern of the cocaine- and amphetamine-regulated transcript (CART) immunoreactivity in the preoptic area of the pig

Review and perspectives of physiological mechanisms underlying genetically-based resistance of the Pacific oysterCrassostrea gigasto summer mortality

Osteoporosis in the home health care setting: A window of opportunity?

Contact Info

Product

Resources

About