Association of dietary patterns with serum adipokines among Japanese: a cross-sectional study

Abstract

BackgroundDiet may influence disease risk by modulating adipokines. Although some foods and nutrients have been linked to circulating adipokine levels, little is known about the role of dietary patterns on adipokines. We investigated the association between major dietary patterns and circulating levels of adiponectin, leptin, resistin, visfatin, and plasminogen activator inhibitor-1 (PAI-1) in a working population.MethodsThe subjects were 509 employees (296 men and 213 women), aged 20 to 65 years, of two municipal offices. Serum adipokines were measured using a Luminex suspension bead-based multiplexed array. Dietary patterns were derived by using principal component analysis of the consumption of 52 food and beverage items, which were ascertained by a validated diet history questionnaire. Multiple regression analysis was performed to assess the association between dietary pattern scores and adipokine concentrations, with adjustment for potential confounders.ResultsThree major dietary patterns were extracted: a Japanese, a Westernized breakfast, and a meat food patterns. Of these, we found significant, inverse associations of the Westernized breakfast pattern, which was characterized by higher intake of confectioneries, bread, and milk and yogurt but lower intake of alcoholic beverages and rice, with serum leptin and PAI-1 concentrations in a fully adjusted model (P for trend = 0.04 for both leptin and PAI-1). The other adipokines were not significantly associated with any dietary pattern.ConclusionThe Westernized breakfast dietary pattern may be associated with lower circulating levels of leptin and PAI-1.

Dietary Patterns and Its Associations with Adipokines (Adiponectin and Leptin) among Adults: A Narrative Review

“…In a hospital-based case-control study for type 2 diabetes in Kumasi (diabetes cases, 538; controls, 668. According to Kashino et al (2015) diet have been identified as one of the modifiable factors that may affect adipokines such as adiponectin and leptin which are the important biochemical indices that might have a role in health and disease. Hence, it is important to see the association of adiponectin and leptin concentration with different types of dietary patterns.…”

“…Leptin, adiponectin, visfatin and tumour necrosis factor-α are among a wide range of adipokines that responsible for majority of endocrine, metabolic and vascular disorder related to obesity and obesity mediated adverse effects on glucose and lipid metabolism (JafariVayghan et al 2015;Monzillo et al 2003)adiponectin, resistin, tumor necrosis factor-alpha (TNF-alpha. Leptin concentration has been associated with a higher risk of type 2 diabetes, hypertension and chronic heart disease (Kashino et al 2015). According to Jafari-Vayghan et al (2015) the role in the regulation of food intake and energy expenditure is exerted by the leptin.…”

“…Besides similar to leptin, lifestyle-related factors such as physical activity and diet play a significant role in adiponectin concentration. Therefore, as adipokines; leptin and adiponectin are presumed to be biochemical predictors of many chronic non-communicable diseases such as diabetes, hypertension and coronary heart disease, it is crucial to discover modifiable factors including the pattern of diet that have an effect on these adipokines (Kashino et al 2015).…”

Exploration of micro- and macronutrient consumption and leverage of interaction with adipokines among Jordanian adults

“…Dietary components may modulate the risk of diseases by altering the levels of adipokines secretion and/or sensitivity [33,44,45]. In this study of Jordanian adults, we highlighted a few associations between dietary consumption of macro-and micro-nutrients and serum levels of leptin, adiponectin, IL-6, resistin, as well as leptin/adiponectin ratio.…”

“…Some of these nutrients includeomega-3 fatty acid [21,22], protein [23], sucrose [24], and dietary [22,25], or foods such as vegetables and fruits [26], whole grain [27], fish [28,29], and legumes [30]. However, other studies showed no association between some dietary component [s] such as vitamins and minerals with adipokine levels [31][32][33]. Studies examined the effect of dietary intake of vitamins and minerals on serum Background and Aim: Findings related to nutrient intakes and levels of adipokines concentrations are inconclusive.…”