People with anxiety and depression are more worried. This worry can weaken their immune system and make them vulnerable to diseases. This study attempted to evaluate the effectiveness of CFT on depression and anxiety in patients with COVID-19. The study had a quasi-experimental pretest-posttest design with a control group. The statistical population included 30 men who underwent quarantine for COVID-19 in 2021. Participants were chosen through convenience sampling and then were randomly assigned to experimental and control groups. In the experimental group, CFT treatment was performed in 10 sessions of 90 minutes. Beck Depression and Anxiety Questionnaires were used to collect the required data. Data were analyzed using SPSS 21 software and multivariate covariance analysis (MANCOVA). The results showed a significant difference between the mean scores of depression and anxiety in the experimental and control groups (p <0.05). The effect of this treatment on reducing the scores of depression and anxiety was 51% and 68%, respectively. Based on the results, CFT can reduce anxiety and depression in patients with COVID-19 disease. It is suggested that this intervention can be used in psychological treatment programs.