Association of interatrial block with development of atrial fibrillation

Interatrial conduction can be accurately determined using standard 12-lead electrocardiography: Validation of P-wave morphology using electroanatomic mapping in man

“…Firstly, it offers a simple, non-invasive method of determining interatrial conduction, which is likely to reflect the propensity for atrial arrhythmia 14,17,18 in large patient cohorts. It is also likely to offer a means of optimizing the choice of septal pacing site in order to resynchronize the atria when pacemaker therapy is chosen for treatment of patients with severe paroxysmal atrial fibrillation.…”

“…15,16 Interatrial block of any degree has been shown to be associated with a high propensity for atrial arrhythmia, including atrial fibrillation. 14,17,18 However, the risk of developing atrial arrhythmia is substantially higher in cases of advanced interatrial block. 18 With the exception of these rather crude indices of impaired interatrial conduction, it has not until now been possible to extract any further information regarding interatrial conduction from the standard 12-lead ECG.…”

Bachmann’s Bundle

“…1 Disruption of the bundle's structure causes interatrial conduction block (IAB), 2 which is associated with development of various atrial tachyarrhythmias 3,4 and with electromechanical dysfunction of the left atrium. 5 Technological progress providing sophisticated mapping and imaging techniques in the past decade has increased our knowledge of specific anatomic structures and their role in development of both atrial brady-and tachyarrhythmias.…”

Prognostic Value of P Wave for Developing Atrial Fibrillation

“…[51][52][53] Histology marked by interstitial fibrosis, [54][55][56] uncoupling of muscle bundle, 57 altered distribution of gap junction, 58,59 and inflammation 60 underlies slow conduction, giving rise to P wave prolongation. Several studies [61][62][63][64][65][66][67][68] determined P-wave duration.…”