2017
DOI: 10.1007/s13365-017-0527-y
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Association of long-term patterns of depressive symptoms and attention/executive function among older men with and without human immunodeficiency virus

Abstract: Older HIV-infected men are at higher risk for both depression and cognitive impairments, compared to HIV-uninfected men. We evaluated the association between longitudinal patterns of depressive symptoms and attention/executive function in HIV-infected and HIV-uninfected men aged 50+ years to understand whether HIV infection influenced the long-term effect of depression on attention/executive function. Responses to the Center for Epidemiologic Studies—Depression scale and attention/executive function tests (Tra… Show more

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Cited by 6 publications
(9 citation statements)
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“…Findings are consistent with studies in HIV-individuals demonstrating that primary NCI among depressed individuals are in psychomotor speed/attention (TMT-A, Stroop, Digit Symbol Substitution) and executive function (TMT-B) 64 ; sex differences were not examined. In HIV, similar patterns are seen among mixed samples of HIV+ and HIVindividuals 16,30,65 .…”
Section: Discussionmentioning
confidence: 59%
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“…Findings are consistent with studies in HIV-individuals demonstrating that primary NCI among depressed individuals are in psychomotor speed/attention (TMT-A, Stroop, Digit Symbol Substitution) and executive function (TMT-B) 64 ; sex differences were not examined. In HIV, similar patterns are seen among mixed samples of HIV+ and HIVindividuals 16,30,65 .…”
Section: Discussionmentioning
confidence: 59%
“…Additionally, we did not assess other diagnostic comorbidities commonly cooccuring with depression including anxiety (not assessed in MACS) and substance use disorders (although we statistically controlled). Finally, while there were differences in the data collection time frame in the two cohorts, it is unlikely that these differences led to a bias towards or against visits completed while a participant was depressed as depressive symptom trajectories are relatively stable in individuals 30 . Despite limitations, few studies have sufficient statistical power to examine whether the depression-NCI associations differ by HIV-serostatus and sex.…”
Section: Discussionmentioning
confidence: 99%
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