Association of Low Vitamin D With Pre Eclampsia

Abstract

Objective: To determine the association of preeclampsia and vitamin D deficiency.
 Study design: Cohort study.
 Place and duration of study: Gynecology Department, Khwaja Muhammad Safdar Medical College, during 01-07-2018 to 31-12-2018.
 Material and Methods: In this study the pregnant females irrespective of their gravida and parity status and having gestational age more than 20 weeks were included. The cases that had vitamin D level lower were labelled as cases and those with normal levels as controls. They these cases were followed monthly until delivery and during this period they were followed for protein urea and BP to label pre eclampsia.
 Results: In this study 100 cases were selected. 50 in each group. Mean age in case and control group was 29.57±4.57 vs 28.43±3.79 years and mean duration of gestation at presentation was 26.43±5.11 vs 27.42±5.23 weeks. There were 39 vs 41 multigravida and 37 vs 38 uneducated females in cases and control group respectively. Preeclampsia was seen in 4 (08%) of control and 14 (28%) cases with odd ration of 4.47 (1.35 to 14.75) with p value 0.01.
 Conclusion: There is significant association of low vitamin D level and risk of pre eclampsia.
 Key words; pre eclampsia, vitamin D, Hypertension.