Association of malnutrition-inflammation score, dialysis-malnutrition score and serum albumin with novel risk factors for cardiovascular diseases in hemodialysis patients

As’habi, Atefeh; Tabibi, Hadi; Hedayati, Mehdi; Mahdavi‐Mazdeh, Mitra; Nozary-Heshmati, Behnaz

doi:10.3109/0886022x.2014.967615

Cited by 22 publications

(18 citation statements)

References 24 publications

(37 reference statements)

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“…By analyzing the nutritional status as a risk factor for cardiovascular disease in those patients, it was observed, through the regression model, that individuals with malnutrition had a higher prevalence of moderate and high cardiovascular risk. In Tehran, a study with 291 hemodialysis patients also found a significant association between malnutrition and increased risk of cardiovascular disease [27]. Moreover, Leavey et al [28] found a significant association between malnutrition and morbidity and mortality associated with cardiovascular disease in patients undergoing hemodialysis.…”

Section: Discussionmentioning

confidence: 97%

Malnutrition and cardiovascular risk in haemodialysis patients with chronic kidney disease

et al. 2019

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Objective To verify the association between nutritional status and traditional and non-traditional cardiovascular risk factors in haemodialysis patients. Methods A cross-sectional study with 132 patients over 18 years of age on haemodialysis to evaluate nutritional status through Subjective Global Assessment. Information on traditional and non-traditional cardiovascular disease risk factors were obtained using a structured questionnaire; the Framingham score was also used to assess cardiovascular risk. Data analysis was performed using the Chi-square Test or Fischer Exact Test and a Log-binomial Regression Model. Results Malnutrition affected 31.1% of patients. Among them, a higher percentage of smokers (p=0.016), former smokers (p=0.034) and diabetes Mellitus patients (p=0.001) were detected. Malnutrition was found to be 4.53 times more prevalent in diabetic individuals (95%CI: 1.99-10.27) and 2.26 times more prevalent among former smokers (95%CI: 1.04-4.95). Malnourished individuals exhibited a 4.03 times prevalence of moderate to severe cardiovascular risk. Conclusion A high prevalence of malnutrition and of other risk factors for cardiovascular disease were observed. Such factors included diabetes Mellitus, smoking and former smoker conditions and were associated with malnutrition. Inaddition, it was found that malnourished individuals were more likely to develop cardiovascular disease within 10 years.

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Section: Discussionmentioning

confidence: 97%

Malnutrition and cardiovascular risk in haemodialysis patients with chronic kidney disease

et al. 2019

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“…Blood sample collection. Blood samples were collected according to the regular method (28). Fasting venous blood was extracted from 200 patients with uremia for detection of serum inflammatory factors.…”

Section: Methodsmentioning

confidence: 99%

CRP, IL‑2 and TNF‑α level in patients with uremia receiving hemodialysis

Yin

et al. 2017

Mol Med Report

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Uremia is a serious threat to health. Infection associated with inflammation frequently occurs in patients with uremia during hemodialysis. This study aimed to investigate the association between serum inflammatory factors and uremia in patients prior to and following hemodialysis. Patients with uremia (n=200) receiving continuous high throughput hemodialysis that had hospital‑acquired infection were enrolled between August 2013 and August 2015. Additionally, 200 cases of healthy volunteers were selected as the control. Reverse transcription‑polymerase chain reaction, ELISA and western blotting were performed to determine serum C‑reactive protein (CRP), interleukin 2 (IL‑2), and tumor necrosis factorα levels (TNF‑α) prior to hemodialysis and 8 months after hemodialysis to explore the association of CRP, IL‑2 and TNF‑α with uremia. CRP, IL‑2 and TNF‑α levels were lower at 8 months after hemodialysis than before, and the difference was statistically significant. CRP, IL‑2 and TNF‑α levels in uremia patients at 8 months after hemodialysis were similar with that in the normal control. CRP expression in patients with uremia was positively correlated with IL‑2 and TNF‑α expression. Patients with uremia with hospital‑acquired infection receiving continuous high throughput blood purification presented increased levels of inflammatory factor in the serum. In conclusion, uremia patients receiving maintenance hemodialysis with hospital‑acquired infection had increased serum inflammatory factors and high throughput hemodialysis significantly decreased CRP, IL‑2 and TNF‑α levels in the serum, suggesting that high throughput hemodialysis may be beneficial for the prevention of the infections in uremia patients.

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“…Los sistemas de escalas nutricionales m SGA (subjective global assessment of nutritional status) es una escala simple y barata, con una alta aplicabilidad en la práctica clínica (18,28) . La escala PENS (protein-energy nutritional status) logra determinar una relación de la mortalidad con el valor sérico de la albúmina (23) .…”

Section: Estudios Complementariosunclassified

Desnutrición en Enfermo Renal Crónico

Vargas

2019

RC_UCR-HSJD

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La desnutrición proteico-energética es una complicación usual en la población con trastorno renal, esta se ve asociado de forma importante con la morbi mortalidad de los pacientes, principalmente de aquellos que se encuentran en diálisis. El proceso fisiopatológico es complejo y actúa como un círculo vicioso en esta población. El diagnóstico oportuno, la prevención y el tratamiento generan un impacto positivo en la población nefrópata, tanto en diálisis como en prediálisis.

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Association of malnutrition-inflammation score, dialysis-malnutrition score and serum albumin with novel risk factors for cardiovascular diseases in hemodialysis patients

Cited by 22 publications

References 24 publications

Malnutrition and cardiovascular risk in haemodialysis patients with chronic kidney disease

Malnutrition and cardiovascular risk in haemodialysis patients with chronic kidney disease

CRP, IL‑2 and TNF‑α level in patients with uremia receiving hemodialysis

Desnutrición en Enfermo Renal Crónico

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