Association of marital status with stage and survival in patients with mycosis fungoides: A population‐based study

Abstract

BACKGROUNDMycosis fungoides (MF), characterized by a monoclonal proliferation of CD4-positive T cells, is the most common type of cutaneous T-cell lymphoma (CTCL) and constitutes almost 50% of all primary cutaneous lymphomas. 1 According to a newly published study, the incidence of MF increased from 3.0 per million person-years in the 1970s to 5.9 in the 2010s, 2 with a higher incidence in Blacks. 3 MF generally affects adult or elderly patients with a male-to-female ratio of 1.6-2.0:1. 1 Cases of children and adolescents, however, have also been reported. 4,5 Patients

Effects of marital status on survival of retroperitoneal liposarcomas stratified by age and sex: A population‐based study

“…Our findings suggested that divorced patients had more advanced disease stages at diagnosis, a finding that was also shown in patients with mycosis fungoides, lung neuroendocrine neoplasms, and melanoma 45–47 . There are several potential interpretations of this phenomenon.…”

“…Our findings suggested that divorced patients had more advanced disease stages at diagnosis, a finding that was also shown in patients with mycosis fungoides, lung neuroendocrine neoplasms, and melanoma. [45][46][47] There are several potential interpretations of this phenomenon. Physical examination of married patients is conducted regularly under the supervision of their spouses before being diagnosed, and married patients are more likely to be diagnosed at an earlier stage.…”

“…Moreover, cancer patients have high levels of anxiety, depression, and distress. Previous studies have revealed that psychological stress could lead to tumor progression by negatively affecting the normal function of the immune and endocrine systems 45,48,49 . Married patients can share their emotional burden and receive emotional and financial support from their spouses 40 .…”

Marital status and survival in cancer patients: A systematic review and meta‐analysis

“…The association between marital status and better survival was found in two studies with patients with gastric cancer, 36,68 and in one study each on patients with epithelial ovarian, 66 esophageal, 53 colorectal, 67 liver, 69 renal, 71 thyroid, 58 kidney, 34 gallbladder, 60 endometrial, 82 head and neck, 83 breast, 32 rectal, 81 lung, 79 pancreatic 86 and laryngeal cancer 55 . The association was also found in one study each on patients with bladder urothelial carcinoma, 72 astrocytoma, 73 spinal cord tumours, 87 glioblastoma multiforme, 74 renal cell carcinoma, 76 cutaneous melanoma, 77 uveal melanoma, 54 laryngeal cancer, 55 lung adenocarcinoma 64 and mycosis fungoides, 50 and in one study on patients with various cancer types 85 …”

“…The sub‐category single versus married patients was compared in eight studies. All but two 50,51 reported that married patients had higher overall survival rates than single patients. The association was found in studies on patients with cervical, 52 esophageal, 53 uveal melanoma, 54 laryngeal cancer, 55 soft tissue sarcoma 56 and in one study with various cancer types 25 .…”