Association of plasma atrial natriuretic peptide, n-terminal proatrial natriuretic peptide, and brain natriuretic peptide levels with coronary artery stenosis in patients with normal left ventricular systolic function

Nishikimi, Toshio; Mori, Yoshihide; Ishimura, Kimihiko; Yagi, Hiroshi; Yabe, Akihisa; Horinaka, Shigeo; Matsuoka, Hiroaki

doi:10.1016/j.amjmed.2003.12.022

Cited by 30 publications

(30 citation statements)

References 37 publications

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“…The main diagnostic efficacy of this test consists of its high negative predictive value suggesting reliable exclusion of left ventricular dysfunction. Data concerning the diagnostic performance of NT-proANP in regard to left ventricular function among patients after myocardial infarction are conflicting [15,16]. For identifying patients who were clinically suspicious for heart failure, NT-proBNP and BNP were better markers than NT-proANP for mild systolic left ventricular dysfunction which was shown by ROC curves [17].…”

Section: Accuracy Of Natriuretic Peptides For the Diagnosis Of Impairmentioning

confidence: 97%

Midregional pro-atrial natriuretic peptide is a useful indicator for the detection of impaired left ventricular function in patients with coronary artery disease

Elmas¹,

Brueckmann²,

Lang³

et al. 2008

International Journal of Cardiology

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Section: Accuracy Of Natriuretic Peptides For the Diagnosis Of Impairmentioning

confidence: 97%

Midregional pro-atrial natriuretic peptide is a useful indicator for the detection of impaired left ventricular function in patients with coronary artery disease

Elmas¹,

Brueckmann²,

Lang³

et al. 2008

International Journal of Cardiology

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“…In their study, BNP had no relation to coronary artery stenosis, although NT-proBNP was not measured. 21 Nakagawa et al reported that BNP but not ANP levels increased in proportion to the scintigraphic myocardial infarction size despite the lack of heart failure in aymptomatic patients with previous myocardial infarction. 22 Choi et al reported that the BNP level correlated with echocardiographic wall motion score index and Gensini score in unstable angina and non-ST elevation myocardial infarction patients, respectively.…”

Section: Discussionmentioning

confidence: 99%

N-Terminal Pro-B-Type Natriuretic Peptide Predicts Significant Coronary Artery Lesion in the Unstable Angina Patients With Normal Electrocardiogram, Echocardiogram, and Cardiac Enzymes

Hong

Yoon

Ahn

et al. 2005

Circ J

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“…[9][10][11][12] The NT-proBNP level is affected by demographic variables such as age, gender, and ethnicity, and clinical characteristics such as hypertension and renal function. 13,14) Recent reports suggest that obesity, as indexed by elevated body mass index (BMI), also affects BNP and NT-proBNP levels, with lower circulating levels in those with a higher BMI.…”

mentioning

confidence: 99%

N-Terminal Pro-B-Type Natriuretic Peptide Level Is Depressed in Patients With Significant Coronary Artery Disease Who Have High Body Mass Index

et al. 2008

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SUMMARYThe aim of this study was to determine how body mass index (BMI) influences the N-terminal pro-B-type natriuretic peptide (NT-proBNP) level in patients with significant coronary artery disease (CAD).A total of 348 patients (61.5 ± 9.2 years, male 67.5%) who had normal left ventricular systolic function were enrolled. All patients underwent percutaneous coronary intervention. We excluded patients with acute myocardial infarction, chronic heart failure, or renal dysfunction. Baseline NT-proBNP level was measured on admission. All underwent follow-up (F-U) coronary angiography (CAG) and the F-U NT-proBNP level was measured before F-U CAG. The patients were divided into two groups: an NT-proBNP < 100 pg/ mL group (group I, n = 228) and an NT-proBNP > 200 pg/mL group (group II, n = 120). BMI was significantly higher in group I than that in group II (26.5 ± 2.2 versus 22.9 ± 2.5 kg/m 2 , P < 0.001). The level of NT-proBNP was negatively correlated with BMI and the levels of hemoglobin and apolipoprotein A1, and positively correlated with age, lipoprotein (a), and the Gensini score. In multivariate analysis, BMI was significantly related to a low NT-proBNP level in patients with CAD (odds ratio, 6.83; 95% confidence interval, 2.67-17.47; P < 0.001).The NT-proBNP level was not elevated in patients with a high BMI despite having significant CAD, and BMI was significantly related to a low NT-proBNP level in patients with significant CAD. (Int Heart J 2008; 49: 403-412)

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Association of plasma atrial natriuretic peptide, n-terminal proatrial natriuretic peptide, and brain natriuretic peptide levels with coronary artery stenosis in patients with normal left ventricular systolic function

Cited by 30 publications

References 37 publications

Midregional pro-atrial natriuretic peptide is a useful indicator for the detection of impaired left ventricular function in patients with coronary artery disease

Midregional pro-atrial natriuretic peptide is a useful indicator for the detection of impaired left ventricular function in patients with coronary artery disease

N-Terminal Pro-B-Type Natriuretic Peptide Predicts Significant Coronary Artery Lesion in the Unstable Angina Patients With Normal Electrocardiogram, Echocardiogram, and Cardiac Enzymes

N-Terminal Pro-B-Type Natriuretic Peptide Level Is Depressed in Patients With Significant Coronary Artery Disease Who Have High Body Mass Index

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