Association of Prevascular Vitreous Fissures and Cisterns With Vitreous Degeneration as Assessed by Swept Source Optical Coherence Tomography

Abstract

Swept source optical coherence tomography imaging can identify PVF and cisterns occurring in the context of age-related VD, and PVF appeared to be possible precursors of cisterns.

OCT En Face Analysis of the Posterior Vitreous Reveals Topographic Relationships among Premacular Bursa, Prevascular Fissures, and Cisterns

“…We have previously hypothesized the presence of PVF and cisterns in vivo based on limited crosssectional OCT sampling. 23 We also postulated that the PVFs are precursors to cisterns, since the base of both structures appeared to overlie superficial retinal blood vessels, and there was a trend towards an increasing prevalence of cisterns with advancing age, while the prevalence of PVFs declined. 23 It has been suggested that the development of PVFs results from a lack of hyalocytes overlying the retinal blood vessels.…”

“…23 We also postulated that the PVFs are precursors to cisterns, since the base of both structures appeared to overlie superficial retinal blood vessels, and there was a trend towards an increasing prevalence of cisterns with advancing age, while the prevalence of PVFs declined. 23 It has been suggested that the development of PVFs results from a lack of hyalocytes overlying the retinal blood vessels. 5,23 Subsequent syneresis may then lead to the expansion of the PVFs, eventually forming cisternal spaces.…”

“…23 It has been suggested that the development of PVFs results from a lack of hyalocytes overlying the retinal blood vessels. 5,23 Subsequent syneresis may then lead to the expansion of the PVFs, eventually forming cisternal spaces. Vitreous degeneration may also be responsible for the connection of the premacular bursa and area of Martegiani, as well as the formation of fissure planes.…”

An Assessment of Vitreous Degeneration in Eyes with Vitreomacular Traction and Macular Holes

“…Our current understanding of posterior vitreous anatomy has recently been augmented by swept-source optical coherence tomography (SS-OCT) which allows an enhanced depth of field [2–4]. Furthermore, manipulation of image capture using standard spectral-domain optical coherence tomography (SD-OCT) allows for improved visualization of structures within the posterior vitreous [5, 6].…”

Giant premacular bursa: a novel finding of the posterior vitreous in two patients with Stickler syndrome type 1 revealed by swept-source optical coherence tomography

“…Given the enlargement of the bursa in the 12-yearold, one may hypothesize that this either represents very early degeneration or may, in fact, be congenital or acquired in very early childhood. In support of early degeneration, perimacular cisterns noted in the cortical vitreous have recently been correlated with higher grades of vitreous degeneration by Pang and associates [6]. Examining younger affected individuals and following them longitudinally will help elucidate this question.…”