Association of psychosocial adversity and social information processing in children raised in a low-resource setting: an fNIRS study

Pirazzoli, Laura; Sullivan, Eileen M.; Xie, Wanze; Richards, John E.; Bulgarelli, Chiara; Lloyd‐Fox, Sarah; Shama, Talat; Kakon, Shahria Hafiz; Haque, Rashidul; Petri, William A.; Nelson, Charles A.

doi:10.1016/j.dcn.2022.101125

Cited by 9 publications

(34 citation statements)

References 75 publications

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“…Univariate analyses with samples from lowand middle-income countries mirror findings from high-income samples, with social selectivity (i.e., differences in activation between social versus non-social stimuli) present at 6 months but more localized as infants get older (see Blasi et al, 2019 for review). Moreover, data from the sample we draw on in the present study confirm that infants at 6, 24, and 36 months show specialization to social stimuli in cortical regions (Pirazzoli et al, 2022). However, how patterns of connectivity change with age and how these patterns are impacted by socioeconomic status remains unknown.…”

Section: The Development Of Social Perception Network In Low-and Midd...supporting

confidence: 65%

“…Finally, data from the sample we draw on in the present study showed that, for 6-, 24-, and 36month-old infants, social selectivity is found in the left and right inferior frontal gyrus and posterior superior temporal sulcus/ temporoparietal junction (Pirazzoli et al, 2022).…”

Section: The Development Of Social Perception Network In Low-and Midd...mentioning

confidence: 48%

“…Reliably, it has been reported that specific brain regions show consistent patterns of responses to social versus non-social stimuli, in both high-income and low-income samples, and across numerous geographic sub-populations of infants being raised in different cultures (e.g., the United Kingdom [Farroni et al, 2013;Hakuno et al, 2018Hakuno et al, , 2020Lloyd-Fox et al, 2009], the Netherlands [Braukmann et al, 2018], the Gambia [Lloyd- Fox et al, 2014Fox et al, , 2017, Bangladesh [Perdue et al, 2019;Pirazzoli et al, 2022], Japan [Kobayashi et al, 2011;Nakato et al, 2011], and the United States [Fava et al, 2014]). Importantly, these studies provide evidence of focal activation within specific regions of the brain that appear to be engaged during the processing of social stimuli.…”

Section: The Development Of Social Perception Network In Low-and Midd...mentioning

confidence: 99%

“…In the present study, we analyzed fNIRS data collected from a large sample of 6-and 24month Bangladeshi infants from low-and middle-income cohorts (Pirazzoli et al, 2022). We take a task-based functional connectivity approach to understand the neural networks underlying social processing in infancy, how these networks change across the first 2 years of life, and whether they are affected by exposure to adversity.…”

Section: The Development Of Social Perception Network In Low-and Midd...mentioning

confidence: 99%

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The Development of Social Perception Networks in Low- and Middle-Income Infants: Longitudinal Assessments of fNIRS Background Functional Connectivity

Burr¹,

Pirazzoli²,

Dopierała³

et al. 2023

Preprint

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Shortly after birth, human infants demonstrate behavioural selectivity to social stimuli. However, the neural underpinnings of this selectivity are largely unknown. Here we examine patterns of functional connectivity to determine how regions of the brain interact while processing social stimuli and how these interactions change during the first two years of life. Using functional near-infrared spectroscopy (fNIRS), we measured functional connectivity at 6 (n = 183) and 24 (n = 123) months of age in infants from Bangladesh who were exposed to varying levels of environmental adversity (i.e., low- and middle-income cohorts). We employed a background functional connectivity approach that regresses out the effects of stimulus-specific variables known to affect functional connectivity. At 6 months, the two cohorts had similar fNIRS patterns, with moderate connectivity estimates for regions within and between hemispheres. At 24 months, the patterns diverged for the two cohorts. Global (brain-wide) connectivity estimates increased from 6 to 24 months for the low-income cohort and decreased for the middle-income cohort. In particular, connectivity estimates among regions of interest (ROIs) within the right hemisphere decreased for the middle-income cohort, providing evidence of neural specialization by two years of age. These findings provide insights about the impact of early environmental influences on functional brain development relevant to the processing of social stimuli.

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Section: The Development Of Social Perception Network In Low-and Midd...supporting

confidence: 65%

Section: The Development Of Social Perception Network In Low-and Midd...mentioning

confidence: 48%

Section: The Development Of Social Perception Network In Low-and Midd...mentioning

confidence: 99%

Section: The Development Of Social Perception Network In Low-and Midd...mentioning

confidence: 99%

See 2 more Smart Citations

The Development of Social Perception Networks in Low- and Middle-Income Infants: Longitudinal Assessments of fNIRS Background Functional Connectivity

Burr¹,

Pirazzoli²,

Dopierała³

et al. 2023

Preprint

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“…The majority of these studies are embedded within larger-scale global health studies, which has meant that the technique is also increasingly applied in longitudinal (0 to 5/7 years) and/or multiple-age-group (5 to 15 time points) experimental designs. 27 – 32 Further, in a new clinical efficacy trial of nutritional intervention in The Gambia (Improving Infant Neurocognitive Development and Growth Outcomes with Micronutrients Trial; 10.1186/ISRCTN15063705), fNIRS will be applied longitudinally in a sample of 600 infants, which, to our knowledge, will be the largest fNIRS developmental study to date. By integrating fNIRS into these multimeasure, large-scale studies, researchers hope to better understand early trajectories of brain development.…”

Section: Bringing Developmental Neuroimaging Into More Ecologically V...mentioning

confidence: 99%

Using functional near-infrared spectroscopy to study the early developing brain: future directions and new challenges

et al. 2023

Self Cite

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. Significance Functional near-infrared spectroscopy (fNIRS) is a frequently used neuroimaging tool to explore the developing brain, particularly in infancy, with studies spanning from birth to toddlerhood (0 to 2 years). We provide an overview of the challenges and opportunities that the developmental fNIRS field faces, after almost 25 years of research. Aim We discuss the most recent advances in fNIRS brain imaging with infants and outlines the trends and perspectives that will likely influence progress in the field in the near future. Approach We discuss recent progress and future challenges in various areas and applications of developmental fNIRS from methodological and technological innovations to data processing and statistical approaches. Results and Conclusions The major trends identified include uses of fNIRS “in the wild,” such as global health contexts, home and community testing, and hyperscanning; advances in hardware, such as wearable technology; assessment of individual variation and developmental trajectories particularly while embedded in studies examining other environmental, health, and context specific factors and longitudinal designs; statistical advances including resting-state network and connectivity, machine learning and reproducibility, and collaborative studies. Standardization and larger studies have been, and will likely continue to be, a major goal in the field, and new data analysis techniques, statistical methods, and collaborative cross-site projects are emerging.

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Neural correlates of response to joint attention in 2‐to‐5‐year‐olds in relation to ASD and social‐communicative abilities: An fNIRS and behavioral study

Piatti,

Van der Paelt,

Warreyn

et al. 2024

Autism Research

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Autism spectrum disorder (ASD) is associated with life‐long challenges with social cognition, and one of its earliest and most common manifestations is atypical joint attention, which is a pivotal skill in social‐cognitive and linguistic development. Early interventions for ASD children often focus on training initiation of joint attention (IJA) and response to joint attention bids (RJA), which are important for social communication and cognition. Here, we used functional near‐infrared spectroscopy and behavioral measures to test typically developing (TD, n = 17) and ASD children (n = 18), to address the relationship between the neural correlates of RJA and social‐communicative behavior. Group‐level differences were present for RJA‐specific activation over right temporal sites, where TD children showed higher levels of activation during RJA than ASD children, whereas the two groups did not differ in the control condition. Correlations between neural activation and behavioral traits suggest that, in ASD children, neural activation during RJA is related to the frequency of RJA behavior when the former is measured over left temporal sites, and to social affect symptoms when considered for right temporal sites. Possible implications of the evidenced correlations are discussed.

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Association of psychosocial adversity and social information processing in children raised in a low-resource setting: an fNIRS study

Cited by 9 publications

References 75 publications

The Development of Social Perception Networks in Low- and Middle-Income Infants: Longitudinal Assessments of fNIRS Background Functional Connectivity

The Development of Social Perception Networks in Low- and Middle-Income Infants: Longitudinal Assessments of fNIRS Background Functional Connectivity

Using functional near-infrared spectroscopy to study the early developing brain: future directions and new challenges

Neural correlates of response to joint attention in 2‐to‐5‐year‐olds in relation to ASD and social‐communicative abilities: An fNIRS and behavioral study

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