2012
DOI: 10.1016/j.gene.2011.10.016
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Association of the ACE-II genotype with the risk of nephrotic syndrome in Pakistani children

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Cited by 5 publications
(2 citation statements)
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“…In the present study, we observed that ACE (I/D) allelic distribution was not elevated in the control group when compared to the different subsets of nephrotic (SSNS/SRNS) cases, which is in agreement with previous studies from different ethnic populations such as Swedish and Egyptian [22 , 2527] . On the contrary, the ACE -II genotype was found more frequent in SSNS in North Indian and Pakistani children [17 , 28] . However, DD genotype was higher in north Indian population [15] which also coincided with the Egyptein [25] , Turkish [29] and Taiwanese [19] nephrotic children.…”
Section: Discussionmentioning
confidence: 99%
“…In the present study, we observed that ACE (I/D) allelic distribution was not elevated in the control group when compared to the different subsets of nephrotic (SSNS/SRNS) cases, which is in agreement with previous studies from different ethnic populations such as Swedish and Egyptian [22 , 2527] . On the contrary, the ACE -II genotype was found more frequent in SSNS in North Indian and Pakistani children [17 , 28] . However, DD genotype was higher in north Indian population [15] which also coincided with the Egyptein [25] , Turkish [29] and Taiwanese [19] nephrotic children.…”
Section: Discussionmentioning
confidence: 99%
“…Cerebrovascular endothelium was reported to be rich in ACE ( Ehlers and Riordan, 1989 , McGeer and Singh, 1992 ). The ACE (I/D) gene polymorphism was shown to be associated in several diseases including diabetes mellitus ( Inanir et al, 2013 ), nephrotic syndrome ( Shahid et al, 2012 ), Alzheimer's disease ( Narain et al, 2000 ), hypertension, and coronary artery disease ( Dhar et al, 2012 , Zhou et al, 2013 ). In the present study, we carried out a retrospective analysis of ACE (I/D) genotype and allele polymorphism among IS patients from south India.…”
Section: Introductionmentioning
confidence: 99%