Association of tobacco and alcohol use with earlier development of colorectal pathology: should screening guidelines be modified to include these risk factors?

Rueda, Mario; Robertson, Yara; Acott, Alison; Rueda, Steven; Keikhoff, Aaron; Guerrero, Whitney; Mancino, Anne T.

doi:10.1016/j.amjsurg.2012.07.026

Cited by 11 publications

(5 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of this study did not reveal an evidence for significant association between smoking and CRC or between alcohol consumption and CRC which is consistent with the findings from other studies McCleary et al, 2010;Rueda et al, 2012;Nordenvall et al, 2014).…”

Section: Discussionsupporting

confidence: 85%

Association between Dietary and Lifestyle Indices and Colorectal Cancer in Oman: A Case-Control Study

Mafiana

Lawati

Waly

et al. 2018

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

Background:Colorectal cancer (CRC) represents a heterogeneous group of diseases characterized by uncontrolled growth and spread of abnormal cells in the body. CRC vary on the basis of both the biologic features of the disease and its associated lifestyle characteristics. The risk of CRC increases with several modifiable factors including obesity, physical inactivity, a diet high in red or processed meat, heavy alcohol consumption, and possibly inadequate intake of fruits and vegetables. We aimed to establish a baseline data for dietary and lifestyle characteristics of Omani adults diagnosed with CRC.Methods:A Case control study conducted at Sultan Qaboos University Hospital, a referral hospital for CRC patients in Oman, and included 279 subjects (109 diagnosed CRC cases and 170 matched controls). All study subjects were recruited on volunteer basis and personally interviewed for preset questions related to sociodemographic data, anthropometric assessment, dietary intake and physical activity.Results:There was no significant difference between cases and controls regarding smoking, alcohol intake, physical activity and dietary fiber intake. However the enrolled cases were more overweight (OR =3.27. 95% CI: 1.91, 7.27), and, had a higher caloric (p =0.001) and macronutrient intake (carbohydrate: p = 0.001; protein: p = 0.017; saturated fat: P = 0.034) than the controls. In addition, the dietary pattern of the cases was characterized by a trend towards low vegetables and fruits intake.Conclusion:CRC maybe prevented through dietary management of high risk groups. This primary prevention approach will ultimately reduce the burden of CRC in Oman.

show abstract

Section: Discussionsupporting

confidence: 85%

Association between Dietary and Lifestyle Indices and Colorectal Cancer in Oman: A Case-Control Study

Mafiana

Lawati

Waly

et al. 2018

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

show abstract

“…Some experts blame our modern sugary diet and excess body weight, while others think that alterations in intestinal microbiota, physical inactivity, and sedentary life-styles may play a role. A possible role of alcohol use in early-onset CRC should also be taken into account [23][24][25]. In the USA the rate of alcohol use disorders has shot up 50% in the past 10 years -reflecting an 80% spike for women, according to the most recent National Epidemiologic Survey on Alcohol and Related Conditions [26].…”

Section: Colorectal Cancermentioning

confidence: 99%

Alcohol Use and Gastrointestinal Cancer Risk

Scherübl¹

2020

Visc Med

View full text Add to dashboard Cite

Background: Alcohol use is an important and potentially modifiable risk factor for gastrointestinal cancers. The more and the longer a person drinks, the higher the risk of cancer becomes. Even modest use of alcohol may increase cancer risk; 100 g of alcohol per week or less is currently considered to be the limit of low-risk use. Gastrointestinal Cancer Risk: Alcohol is causally associated with oesophageal squamous cell cancer, gastric cancer, hepatocellular carcinoma, colorectal cancer, and most likely also with pancreatic cancer. Alcohol when combined with tobacco smoking or excess body weight can act synergistically to cause gastrointestinal cancer. Exposure to alcohol may have contributed to the recent incidence increases of early-onset gastrointestinal cancers in some Western countries. Conclusions: People with longterm risky alcohol use should be encouraged to join cancer screening programmes. Alcohol cessation appears to be effective in reducing the alcohol-induced, increased cancer risk.

show abstract

“…It has not been clearly established regarding the relationship between alcohol consumption and colorectal adenoma, yet there are several studies describing that alcohol intake impacts on the development of colorectal adenoma. 2 , 5 In order to estimate the amount of alcohol consumption, it was often relying on interviewing but it lacks accuracy and accompanies inter-individual variability considering its nature thereby making it difficult to elucidate exact roles of alcohol intake in reference to colorectal adenoma development. In the current study, we investigated effects of alcohol intake to colorectal adenoma development in patients who underwent colonoscopic polypectomy using not only patients' interview but also results of blood tests and degree of liver diseases by radiologic evaluation.…”

Section: Introductionmentioning

confidence: 99%

Alcohol Drinking Increased the Risk of Advanced Colorectal Adenomas

et al. 2015

View full text Add to dashboard Cite

Background/AimsAge, sex, gene and life style are modulating risks for colon cancer. Although alcohol intake may impact on colorectal adenoma, clear association has not been established yet. We aimed to investigate effects of alcohol consumption on the characteristics of colorectal adenoma.MethodsPatients who underwent colonoscopic polypectomy of colorectal adenoma in the department of gastroenterology of Eulji hospital through 2005 to 2012, having both blood tests and ultrasound or abdominal CT examination were enrolled. The alcohol drinking patients were subdivided into normal or abnormal laboratory group, and alcoholic liver diseases group.Results212 patients with colorectal adenoma were analyzed; advanced adenoma and multiple adenoma were found in 68 (32.0%) and 79 (37.2%) patients. When compared to the nondrinker group (120/212 patients), the alcohol drinker group (92/212 patients) represented significantly high odds ratios (ORs) for advanced adenoma (OR, 2.697; P=0.002), and multiple adenoma (OR, 1.929; P=0.039). Among alcohol drinker (92 patients), the ORs of advanced adenoma were 6.407 (P=0.003) in alcoholic liver diseases group (17 patients), 3.711 (P=0.002) in the alcohol drinker with abnormal lab (24 patients), and 2.184 (P=0.034), in the alcohol drinker with normal lab (51 patients) compared to nondrinker group.ConclusionsThis study showed that alcohol drinking may influence on the development of advanced colorectal adenoma and multiplicity. Especially in the group with alcoholic liver diseases and with abnormal lab presented significantly higher ORs of advanced adenoma.

show abstract

Association of tobacco and alcohol use with earlier development of colorectal pathology: should screening guidelines be modified to include these risk factors?

Cited by 11 publications

References 41 publications

Association between Dietary and Lifestyle Indices and Colorectal Cancer in Oman: A Case-Control Study

Association between Dietary and Lifestyle Indices and Colorectal Cancer in Oman: A Case-Control Study

Alcohol Use and Gastrointestinal Cancer Risk

Alcohol Drinking Increased the Risk of Advanced Colorectal Adenomas

Contact Info

Product

Resources

About