Association of waist circumference with atherogenic cardiovascular risks in centrally obese Myanmar male subjects

Sein, Mya Thanda; Latt, Tint Swe; Ohnmar, Ohnmar

doi:10.4103/2348-8093.155518

Cited by 3 publications

(3 citation statements)

References 22 publications

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“…AIP is being used by some practitioners as a significant predictor of atherosclerosis. It has been suggested that AIP values of <0.1 are associated with low, 0.1 to 0.24 with medium and above 0.24 with high cardiovascular risk [7]. We have studied AIP & observed a significant increase in an AIP ratio of 0.246 in cases when compared to controls (0.106).…”

Section: Fig-3: Comparison Of Cri I and Ii Ac Values In Controls And Casementioning

confidence: 78%

Study of Atherogenic Index of Plasma (AIP) and Other Lipid Indices in Helicobacter Pylori Infection

Mr¹,

Jayaram²,

Meera³

et al. 2019

SIJB

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Helicobacter pylori (H. pylori) is a gram negative bacterium that naturally colonizes the gastric epithelium, which causes chronic gastritis and peptic ulcer disease. Recent studies have shown that it may interfere with many biological processes and influence the occurrence of many diseases outside the stomach. Many studies have proposed a link between H. pylori infection and atherosclerosis. Atherogenic Index of Plasma (AIP) has been considered as a strong marker to predict the risk of atherosclerosis. The present study was done to assess the correlation between AIP and other lipid indices with H. pylori infection. The study comprised of 50 biopsy proven H. pylori cases and 50 age-sex matched controls. Blood samples were collected in fasting state and analyzed for total cholesterol (TC), triglycerides (TG), HDL-cholesterol (HDL) and LDL-cholesterol and the lipid indices were calculated. Lipid indices like AIP, CRI 1 & 2 & AC were significantly higher in H. pylori infected cases compared to controls. Hence these lipid indices can be used for identifying individuals at higher risk of cardiovascular diseases in H. pylori infected patients.

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Section: Fig-3: Comparison Of Cri I and Ii Ac Values In Controls And Casementioning

confidence: 78%

Study of Atherogenic Index of Plasma (AIP) and Other Lipid Indices in Helicobacter Pylori Infection

Mr¹,

Jayaram²,

Meera³

et al. 2019

SIJB

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“…Thus, incorporation of both HOMA-IR and AIP should be done as a standard risk assessment tool towards the development of atherosclerosis and to assess its relationship with IR. [33] When the individual parameters were used to quantify the burden of CMD risk among the study population, the obtained prevalence was comparatively less. On estimating IR by HOMA-IR with the help of FPG and FPI, 28.9% of them showed IR.…”

Section: Discussionmentioning

confidence: 99%

A Cross-sectional Study to Assess Insulin Resistance and Atherogenic Index of Plasma as Predictors of Risk of Cardiometabolic Disease among Undergraduate Medical Students at a Tertiary Care Teaching Hospital, Karnataka

Sannamadhu,

Manjegowda,

Hanumantharaya

2023

JMSH

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Background: Medical profession is known for stress and challenges due to hectic academic schedules which makes students, high-risk candidates for diabetes mellitus, hypertension and cardiometabolic disease (CMD). Surrogate markers such as homeostatic model assessment insulin resistance (HOMA-IR) and atherogenic index of plasma (AIP) along with routine parameters enable early prediction of the disease. Hence, this study aimed at determining HOMA-IR and AIP along with assessment of their correlation with anthropometric and biochemical parameters associated with CMD risk among undergraduate medical students. Methodology : 460 medical students consented to participate in the study. The data related to socio-demographic profile, anthropometry, blood pressure and biochemical parameters such as fasting plasma glucose (FPG), fasting plasma insulin (FPI) and lipid profile was collected and analyzed. HOMA-IR and AIP were calculated. The strength of association between study variables was determined by relevant statistics. Results: The study showed the prevalence of overweight (17.8%), obesity (20.4%), pre-hypertension (37.82%) and hypertension (3.47%). 98.5% of the participants had normal FPG and FPI, whereas 1.5% had impaired levels. Lipid profile analysis showed hypercholesterolemia (3.7%), hypertriglyceridemia (8.1%), increased LDL-c (33.7%) and reduced HDL-c (55.2%). High HOMA-IR and AIP were contributed by 28.9% and 73.3% respectively. HOMA-IR and AIP showed statistically significant positive correlation with CMD risk factors. Conclusion: HOMA-IR and AIP considered as the better predictors of CMD risk among apparently healthy medical students. Thus, incorporation of these surrogate markers along with routine parameters for regular screening can help in early prediction of the risk of CMD among undergraduate medical students. Keywords: Homeostatic model assessment insulin resistance, Atherogenic index of plasma, Cardiometabolic disease, Medical students

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“…To the best of the authors’ knowledge, only one review of six studies exists; it is over 15 years old and does not represent the current literature [ 13 ]. This is important because over recent years, many studies have investigated AIP and numerous have revealed a positive association between AIP and cardiometabolic risk factors [ 14 , 15 , 16 , 17 , 18 ]. Moreover, they found that an AIP value of under 0.11 is associated with a low risk of CVD, and values between 0.11 to 0.21 and upper than 0.21 are associated with intermediate and increased risks, respectively [ 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

The Association between the Atherogenic Index of Plasma and Cardiometabolic Risk Factors: A Review

2023

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Background: Metabolic syndrome (MetS) is a condition caused by a combination of cardiometabolic risk factors (CMR). MetS leads to type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), both of which place a burden on not only the patients but also the healthcare system. Diagnostic criteria for MetS vary, and there is no universal tool to detect it. Recently, many studies have found positive associations between the atherogenic index of plasma (AIP) and some CMR factors. Therefore, a comprehensive review was needed to recapitulate these studies and qualitatively estimate the likelihood of AIP being associated with CMR. We aimed to review and summarise observational data on AIP and CMR factors and verify their association. Materials and Methods: A review of observational studies was conducted by searching “atherogenic index of plasma” in PubMed, One Search, and the Cochrane library. A total of 2068 articles were screened, and 32 were included after excluding paediatric, non-human and interventional studies, and those carried out on cohorts with conditions unrelated to MetS or on lipid-lowering medication. The Newcastle-Ottawa scale was used to assess their quality. Results: Most studies that reported high waist circumference (WC), triglycerides (TG), insulin resistance (IR) and low high-density lipoprotein cholesterol (HDL-C) concentration, also reported high AIP. Few studies investigated blood pressure (BP) and some discrepancies existed between their results. Conclusion: AIP may be associated with WC, TG, IR, and HDL-C. It is unclear if AIP is associated with BP. The current study’s results should be used to inform futureward a meta-analysis to be seen quantitatively. It is also recommended that more cohort studies stratified by gender and ethnicity be performed to ascertain if AIP can predict MetS before it manifests.

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Association of waist circumference with atherogenic cardiovascular risks in centrally obese Myanmar male subjects

Cited by 3 publications

References 22 publications

Study of Atherogenic Index of Plasma (AIP) and Other Lipid Indices in Helicobacter Pylori Infection

Study of Atherogenic Index of Plasma (AIP) and Other Lipid Indices in Helicobacter Pylori Infection

A Cross-sectional Study to Assess Insulin Resistance and Atherogenic Index of Plasma as Predictors of Risk of Cardiometabolic Disease among Undergraduate Medical Students at a Tertiary Care Teaching Hospital, Karnataka

The Association between the Atherogenic Index of Plasma and Cardiometabolic Risk Factors: A Review

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